Novel water-soluble phthalocyanines substituted with phosphonate moieties on the benzo rings

Tetrahedron Letters

Volumn 37, Issue 33, 1996, Pages 5831-5834

  Sharman, Wesley M ^a   Kudrevich, Svetlana V ^a   Van Lier, Johan E ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUND; MACROCYCLIC COMPOUND; ORGANIC SOLVENT; PHOSPHONIC ACID DERIVATIVE; PHOTOSENSITIZING AGENT; PHTHALOCYANINE DERIVATIVE;

ARTICLE; COLUMN CHROMATOGRAPHY; COMPLEX FORMATION; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; INFRARED SPECTROMETRY; PHOSPHORYLATION; PHOTODYNAMIC THERAPY; ULTRAVIOLET SPECTROSCOPY;

EID: 0030581382     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01243-9     Document Type: Article

References (18)

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15. 3). UV-visible, λ, nm (ε) [inDMSO]: 299 (1970), 289 (1940), 260 (4790).
16. max,, nm: compound 3a, 689 [in DMSO], 685 [in triphenylphosphite], compound 3b: 687 [in DMSO].
17. -1 (KBr) 2900 (P-O-H), 1152-1120 (P=O) and 951-943 (P-O-H). UV-visible, λ, nm (log ε) [in 0.01N NaOH], 4a: 679 (5.35), 616 (4.51), 339 (4.82); 4b: 683 (5.33), 614 (4.54), 345 (4.86). UV-visible, λ, nm (log ε) [in pH 5 phosphate buffer], 4a: 616 (4.76). HPLC analysis conducted on a 0.94 x 25 cm column packed with ODS-2, C-18 reversed phase particles, CSC Montreal, and operated with a linear gradient from 100% aqueous sodium phosphate buffer, pH 5.5, to 100% methanol over a period of 30 minutes at a flow rate of 1.5 ml/min and with the UV-visible detector set at 680 nm: compound 4a gave a single peak at 11 minutes and compound 4b gave a single peak at 10.75 minutes.
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