An evaluation of the twofold rule for assessing a positive response in the L5178Y TK(+/-) mouse lymphoma assay

Mutation Research - Genetic Toxicology

Volumn 369, Issue 3-4, 1996, Pages 221-232

  Oberly, T J ^a   Hoffman, W P ^a   Garriott, M L ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Mouse lymphoma assay; Proposed ICH guidelines; Twofold rule

Indexed keywords

ACRIDINE ORANGE; ACRIFLAVINE; ACRYLIC ACID METHYL ESTER; ACRYLONITRILE; BENZENE; BENZIDINE; BENZOIN; CAPROLACTAM; CAPTAN; DIPHENYLNITROSAMINE; FLUORENE; ISONIAZID; MEPYRAMINE MALEATE; MESYLIC ACID ETHYL ESTER; METHAPYRILENE; METHOXYCHLOR; MITOMYCIN C; MUTAGENIC AGENT; N (2 FLUORENYL)ACETAMIDE; PHENOBARBITAL; PHENYTOIN; PROFLAVINE; PYRENE; SAFROLE; TRIFLURALIN;

ANIMAL CELL; ARTICLE; LEUKEMIA CELL; LEUKEMIA L 5178 Y; LYMPHOMA; MOUSE; MUTAGEN TESTING; NONHUMAN; PRACTICE GUIDELINE; PRIORITY JOURNAL;

EID: 0030581302     PISSN: 01651218     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1218(96)90027-0     Document Type: Article

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