Sensitive high-performance liquid chromatographic method for the determination of a benzonaphthazepine antipsychotic agent, SCH 39166, and its active metabolite, SCH 40853, in human plasma and its cross-validation with a gas chromatographic method

Journal of Chromatography B: Biomedical Applications

Volumn 682, Issue 2, 1996, Pages 309-313

  Lin, Chin chung ^a   Kim, Hong Ki ^a   Parker, Donald ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Benzonaphthazepine antipsychotic

Indexed keywords

3 CHLORO 6,7,7A,8,9,13B HEXAHYDRO 2 HYDROXY 5H BENZO[D]NAPHTHO[2,1 B]AZEPINE; CYCLOBENZAPRINE; DRUG METABOLITE; ECOPIPAM; NEUROLEPTIC AGENT; UNCLASSIFIED DRUG;

ADULT; ANALYTIC METHOD; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG DETERMINATION; EXTRACTION; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; REPRODUCIBILITY; VOLUNTEER;

EID: 0030581154     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4347(96)00089-8     Document Type: Article

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