Stability and compatibility study of a carboplatin solution in syringes for continuous ambulatory infusion

International Journal of Pharmaceutics

Volumn 138, Issue 1, 1996, Pages 125-128

  Valiere C ^a   Arnaud, P ^a   Caroff, E ^a   Dauphin, J F ^b   Clement G ^c   Brion, F ^a  

^a HÔPITAL ROBERT DEBRÉ   (France)

^b BRISTOL MYERS SQUIBB   (United States)

^c Laboratoire Aguettant   (France)

Author keywords

Carboplatin; Continuous infusion; Plastic compatibility; Stability

Indexed keywords

CARBOPLATIN; PLASTIC;

ARTICLE; DRUG DECOMPOSITION; DRUG INCOMPATIBILITY; DRUG STABILITY; DRUG STORAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; SYRINGE;

EID: 0030581132     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(96)04534-6     Document Type: Article

References (5)

1. Anonymous, Dossier d'AMM du Paraplatine ®, Bristol Myers Squibb, Paris, France.
2. Cheung, Y.W, Cradock, J.G., Vishnuvajjala, B.R. and Flora K.P., Stability of cisplatin, iproplatin, carboplatin and tetraplatin in commonly used intravenous solutions. Am. J. Hosp. Pharm., 44 (1987) 124-130.
3. Sewell, G.J., Riley, C.M. and Rowland, C.G., The stability of carboplatin in ambulatory continuous infusion regimes. J. Clin. Pharm. Ther., 12 (1991) 427-432.
4. Northrott, M., Allsopp, M.A., Powell, L.H. and Sewell, G.J., The stability of carboplatin, diamorphine, 5 fluorouracil and mitozantrone infusions in an ambulatory pump under storage and prolonged in use conditions. J. Clin. Pharm. Ther., 16 (1991) 123-129.
5. Rochard, E. Barthes, D. and Courtois, P., Stability and compatibility study of carboplatin with three portable infusion pump reservoirs. Int. J. Pharm., 101 (1994) 257-262.