Cholesterol esterification is not essential for secretion of lipoprotein components by HepG2 cells

Biochimica et Biophysica Acta - Lipids and Lipid Metabolism

Volumn 1302, Issue 1, 1996, Pages 46-54

  Graham, Annette ^a,b   Wood, Jenny L ^a   Russell, Linda J ^a  

^a WELLCOME RESEARCH LABORATORIES   (United Kingdom)

^b ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

(Liver); acyl CoA:cholesterol acyltransferase inhibitor; Cholesterol biosynthesis; low density lipoprotein receptor; Very low density lipoprotein

Indexed keywords

CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ACYLTRANSFERASE INHIBITOR; CHOLESTEROL ESTER; LIPOPROTEIN;

ARTICLE; CELL SECRETION; CHOLESTEROL ESTERIFICATION; CHOLESTEROL SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIPID ANALYSIS; LIPOPROTEIN SECRETION; PRIORITY JOURNAL;

EID: 0030581123     PISSN: 00052760     EISSN: None     Source Type: Journal    
DOI: 10.1016/0005-2760(96)00030-6     Document Type: Article

References (41)

1. [1] Fielding, C.J. and Fielding, P.E. (1985) in Biochemistry of Lipids and Membranes (Vance, D.E. and Vance, J.E., eds.), pp. 424-430, Benjamin Cummings, CA.
2. [2] Dietschy, J.M., Turley, S.D. and Spady, D.K. (1993) J. Lipid Res. 34, 1637-1659.
3. [3] Ohtani, H., Hajashi, K., Hirata, Y., Dojo, S., Nakashima, K., Nishio, E., Kurushima, H., Saeki, M. and Kajiyama, G. (1990) J. Lipid Res. 31, 1413-1422.
4. [4] Pullinger, C.R., North, J.D., Teng, B.-B., Rifici, V.A., Ronhild de Brito, A.E. and Scott, J. (1989) J. Lipid Res. 30, 1065-1077.
5. [5] Dixon, J.L., Furukawa, S. and Ginsberg, H.N. (1991) J. Biol. Chem. 266, 5080-5086.
6. [6] Vance, D.E. and Vance, J.E. (1985) Can. J. Biochem. Cell. Biol. 63, 870-881.
7. [7] Mookerjea, S., Park, C.E. and Kuksis, A. (1975) Lipids 10, 374-382.
8. [8] Rosenfeld, B. and Lang, J.M. (1966) J. Lipid Res. 7, 10-16.
9. [9] Craig, W.Y., Nutik, R. and Cooper, A.D. (1988) J. Biol. Chem. 263, 13880-13890.
10. [10] Davis, R.A., McNeal, M.M. and Moses, R.T. (1982) J. Biol. Chem. 257, 2634-2640.
11. [11] Noel, S.P., Wong, L., Dolphin, P.J., Dory, L. and Rubinstein, D. (1979) J. Clin. Invest. 64, 674-683.
12. [12] Kris-Etherton, P.M. and Cooper, A.D. (1980) J. Lipid Res. 21, 435-442.
13. [13] Tanaka, M., Jingami, H., Otani, H., Cho, M., Ueda, Y., Arai, H., Nagano, Y., Doi, T., Yokode, M. and Kita, T. (1993) J. Biol. Chem. 268, 12713-12718.
14. [14] Krause, B.R., Anderson, M., Bisgaier, C.L., Bocan, T., Bousley, R., DeHart, P., Essenburg, A., Hamelehle, K., Homan, R., Kieft, K., McNally, W., Stanfield, R. and Newton, R.W. (1993) J. Lipid Res. 34, 279-294.
15. [15] Krause, B.R., Bousley, R.F., Kieft, K.A. and Stanfield, R.L. (1992) Clin. Biochem. 25, 371-377.
16. [16] Krause, B.R., Kieft, K., Auerbach, B., Stanfield, R., Bousley, R. and Bisgaier, C. (1991) Circulation 84, II-138.
17. [17] Schnitzer-Polokoff, R., Compton, D., Boykow, G., Davis, H. and Burrier, R. (1991) Comp. Biochem. Physiol. 99, 665-670.
18. [18] Cianflone, K.M., Yasruel, Z., Rodriguez, M.A., Vas, D. and Sniderman, A.D. (1990) J. Lipid Res. 31, 2045-2055.
19. [19] Wu, X., Sakata, N., Lui, E and Ginsberg, H.N. (1994) J. Biol. Chem. 269, 12375-12382.
20. [20] Ellsworth, J.L., Erickson, S.K. and Cooper, A.D. (1986) J. Lipid Res. 27, 858-874.
21. [21] Gibbons, G.F., Khurana, R., Odwell, A. and Seelaender, M.C.L. (1994) J. Lipid Res. 35, 1801-1808.
22. [22] Chung, B.H., Wilkinson, T., Geer, J.C. and Segrest, J.P. (1980) J. Lipid Res. 21, 284-291.
23. [23] Pittman, R.C. and Taylor, C.A., Jr. (1986) Methods Enzymol. 129, 613-628.
24. [24] Graham, A. and Russell, L.J. (1994) Biochem. J. 298, 579-584.
25. [25] Graham, A., Zammit, V.A. and Brindley, D.N. (1988) Biochem. J. 249, 727-733.
26. [26] Bligh, E.G. and Dyer, W.J. (1959) Can. J. Biochem. Physiol. 37, 911-917.
27. [27] Sviridov, D.D., Safonova, I.G., Pavlov, M.Y., Kosykh, V.A. Podrez, E.A., Antonov, A.S., Fuki, I.V. and Repin, V.S. (1990) Lipids 25, 177-179.
28. [28] Cohen, L.H., van Vliet, A., Roodenburg, L., Jansen, L.M.C. and Griffioen, M. (1993) Biochem. Pharmacol. 45, 2203-2208.
29. [29] Sviridov, D.D., Endo, A., Pavlov, M.Y. and Repin, V.S. (1993) Lipids 28, 569-571.
30. [30] Qin, W., Infante, J., Wang, S.-R. and Infante, R. (1992) Biochim. Biophys. Acta 1127, 57-66.
31. [31] Molowa, D.T. and Cimis, G.M. (1989) Biochem. J. 260, 731-736.
32. [32] Tanaka, H. and Kimura, T., ACAT Inhibitors in Development (1994) Exp. Opin. Invest. Drugs 3, 427-436.
33. [33] Marcetta, C.A., Savoy, Y.E., Freeman, A.M., Long, C.A., Pettini, J.L., Hagar, R.E., Inskeep, P.B., Davis, K., Stucchi, A.F., Nicolosi, R.J. and Hamanaka, E.S. (1994) J. Lipid Res. 35, 1829-1838.
34. [34] Bocan, T.M., Mueller, S.B., Uhlendorf, P.D., Newton, R.S. and Krause, B.R. (1991) Arterioscler. Thromb. 11, 1830-1843.
35. [35] Dashti, N. (1992) J. Biol. Chem. 267, 7160-7169.
36. [36] Furukawa, S. and Hirano, T. (1993) Biochim. Biophys. Acta 1170, 32-37.
37. [37] Ribeiro, A., Mangeney, M., Loriette, C., Thomas, G., Pepin, D., Janvier, B., Chambaz, J. and Bereziat, G. (1991) Biochim. Biophys. Acta 1086, 279-286.
38. [38] Sato, R., Imanaka, T. and Takano, T. (1990) Biochim. Biophys. Acta, 1042, 36-41.
39. [39] Horie, M., Hayashi, M., Satoh, T., Hotta, H., Nagata, Y., Ishida, F. and Kamei, T. (1993) Biochim. Biophys. Acta 1168, 45-51.
40. [40] Salter, A.M., Ekins, N., Al-Seeni, M., Brindley, D.N. and Middleton, B. (1989) Biochem. J. 263, 255-260.
41. [41] Fast, D.G. and Vance, D.E. (1995) Biochim. Biophys. Acta 1258, 159-168.