Phenotypic characterization of neurotensin messenger RNA-expressing cells in the neuroleptic-treated rat striatum: A detailed cellular co-expression study

Neuroscience

Volumn 76, Issue 3, 1996, Pages 763-774

  Augood, S J ^a   Westmore, K ^a   Emson, P C ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

basal ganglia; gene expression; haloperidol; neuroleptic; neurotensin

Indexed keywords

ENKEPHALIN; HALOPERIDOL; MESSENGER RNA; NEUROLEPTIC AGENT; NEUROTENSIN; PHOSPHOPROTEIN DARPP 32; SUBSTANCE P;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; CORPUS STRIATUM; GENE EXPRESSION; IN SITU HYBRIDIZATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030580558     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(96)00449-6     Document Type: Article

References (69)

1. 1 like dopamine receptors on different types of striatal neurons. Brain Res. 568, 235-243.
2. 2. Augood S. J. and Emson P. C. (1992) Pertussis toxin administration increases the expression of proneurotensin and enkephalin A mRNAs in rat striatum. Neuroscience 47, 317-324.
3. 3. Augood S. J., Faull R. L. M. and Emson P. C. (1992) Contrasting effects of raclopride and SCH 23390 on the cellular content of enkephalin A mRNA in rat striatum: a quantitative non-radioactive in situ hybridization study. Eur. J. Neurosci. 4, 102-112.
4. 2 receptor antagonists on proneurotensin mRNA expression in rat striatum. Molec. Brain Res. 9, 341-346.
5. 5. Augood S. J., McGowan E. M. and Emson P. C. (1994) Expression of NMDA receptor subunit NR1 mRNA by identified striatal somatostatin cells. Neuroscience 59, 7-12.
6. 6. Augood S. J., McGowan E. M., Finsen B. R. and Heppelman B. and Emson P. C. (1994) Non-radioactive in situ hybridization using alkaline phosphatase-labelled oligonucleotides. In In Situ Hybridization Protocols for the Brain, pp. 81-97. Academic Press, London.
7. 7. Augood S. J., Westmore K., Faull R. L. M. and Emson P. C. (1993) Neuroleptics and striatal neuropeptide gene expression. Prog. Brain Res. 99, 181-199.
8. 8. Bean A. J., During M. J., Deutch A. Y. and Roth R. H. (1989) Effects of dopamine depletion on striatal neurotensin: biochemical and immunohistochemical studies. J. Neurosci. 9, 4430-4438.
9. 9. Bean A. J. and Hökfelt T. (1992) Reserpine increases striatal neurotensin mRNA levels. Molec. Brain Res. 12, 345-348.
10. 10. Castel M.-N., Morino P., Frey P., Terenius L. and Hökfelt T. (1993) Immunohistochemical evidence for a neurotensin striatonigral pathway in the rat brain. Neuroscience 55, 833-847.
11. 11. Castel M.-N., Morino P. and Hökfelt T. (1993) Modulation of the neurotensin striatonigral pathways by D1 receptors. NeuroReport 5, 281-284.
12. 12. Castel M.-N., Morino P., Nylander I., Terenius L. and Hökfelt T. (1994) Differential dopaminergic regulation of the neurotensin striatonigral and striatopallidal pathways in the rat. Eur. J. Pharmac. 262, 1-10.
13. 13. Checler F. (1994) The preproneurotensin/neuromedin N gene: structural organization, regulation of expression and post-transcriptional events. In Frontiers in Neurobiology: Neuropeptide Gene Expression (ed. Turner A. J.), pp. 133-160. Portland Press, London.
14. 14. Delong M. R. (1990) Primate models of movement disorders of basal ganglia origin. Trends Neurosci. 13, 281-285.
15. 15. Diaz J., Lévesque D., Griffon N., Lammers C. H., Martres M.-P., Sokoloff P. and Schwartz J.-C. (1994) Opposing roles for dopamine D2 and D3 receptors on neurotensin mRNA expression in nucleus accumbens. Eur. J. Neurosci. 6, 1384-1387.
16. 16. Ehrlich M. E., Kunihara T. and Greengard P. (1990) Rat DARPP-32: cloning, sequencing and characterization of the cDNA. J. Molec. Neurosci. 2, 1-10.
17. 17. Emson P. C., Goedert M. and Mantyh P. W. (1985) Neurotensin-containing neurons. In Handbook of Chemical Neuroanatomy (eds Björklund A. and Hökfelt T.), pp. 355-405. Elsevier Science, Amsterdam.
18. 18. Faull R. L. M., Dragunow M. and Villiger J. W. (1989) The distribution of neurotensin receptors and acetylcholinesterase in the human caudate nucleus: evidence for the existence of a third neurochemical compartment. Brain Res. 488, 381-386.
19. 19. Frey P., Fuxe K., Eneroth P. and Agnati L. F. (1986) Effects of acute and long-term treatment with neuroleptics on regional telencephalic neurotensin levels in the male rat. Neurochem. Int. 8, 4229-4434.
20. 20. Gerfen C. R., Engber T. M., Mahan L. C., Susel Z., Chase T. N., Monsma F. J. and Sibley D. R. (1990) D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons. Science 250, 1429-1432.
21. 21. Gerfen C. R. and Young S. III (1988) Distribution of striatonigral and striatopallidal peptidergic neurons in both patch and matrix compartments: an in situ hybridization histochemistry and fluorescent retrograde tracing study. Brain Res. 460, 161-167.
22. 22. Goedert M., Mantyh P. W., Emson P. C. and Hunt S. P. (1984) Inverse relationship between neurotensin receptors and neurotensin-like immunoreactivity in cat striatum. Nature 307, 543-546.
23. 23. Graybiel A. M. (1990) Neurotransmitters and neuromodulators in the basal ganglia. Trends Neurosci. 13, 244-254.
24. 1 and DARPP-32 gene expression in the rat striatum: an in situ hybridization study. Molec. Brain Res. 12, 131-139.
25. 25. Gustafson E. L., Ehrlich M. E., Trivedi P. and Greengard P. (1992) Developmental regulation of phosphoprotein gene expression in the caudate-putamen of rat: an in situ hybridization study. Neuroscience 51, 65-75.
26. 26. Halpain S., Girault J.-A. and Greengard P. (1990) Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices. Nature 343, 369-375.
27. 27. Hemmings H. C. Jr, Walaas S. I., Ouimet C. C. and Greengard P. (1987) Dopaminergic regulation of protein phosphorylation in the striatum: DARPP-32. Trends Neurosci. 10, 377-383.
28. 28. Hersch S. M., Ciliax B. J., Gutekunst C.-A. A., Rees H. D., Heilman C. J., Yung K. K. L., Bolam J. P., Ince E., Yi H. and Levey A. I. (1995) Electron microscopic analysis of D1 and D2 dopamine receptor proteins in the dorsal striatum and their synaptic relationships with motor corticostriatal afferents. J. Neurosci. 15, 5222-5237.
29. 29. Jablonski E., Molomaw E. W., Tulis R. H. and Ruth J. L. (1986) Preparation of oligodeoxy-nucleotide-alkaline phosphatase conjugates and their use as hybridization probes. Nucl. Acids Res. 14, 6115-6128.
30. 30. Jennes L., Stumpf W. and Kalivas P. W. (1982) Neurotensin: topographical distribution in rat brain by immunohistochemistry. J. comp. Neurol. 210, 211-224.
31. 31. Kawaguchi Y., Hoshimari M., Nawa H. and Nakanishi S. (1986) Sequence analysis of cloned cDNA for rat substance P precursor: existence of a third substance P precursor. Biochem. biophys Res. Commun. 139, 1040-1046.
32. 32. Kislauskis E., Bullock B., McNeil S. and Dobner P. R. (1988) The rat gene encoding neurotensin and neuromedin N. J. biol Chem. 263, 4963-4968.
33. 33. Kiyama H. and Emson P. C. (1991) Colchicine induced proneurotensin gene expression in rat striatum and hypothalamus. Molec. Brain Res. 9, 353-358.
34. 34. Laduron P. M. (1995) Functional consequences of retrograde axonal transport of receptor-bound neurotensin. Trends pharmac. Sci. 16, 338-343.
35. 35. Landwehrmeyer G. B., Standaert D. G., Testa C. M., Penney J. B. and Young A. B. (1995) NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum. J. Neurosci. 15, 5297-5307.
36. 36. Le F., Cusack B. and Richelson E. (1996) The neurotensin receptor: is there more than one subtype?. Trends pharmac. Sci. 17, 1-3.
37. 37. Le Moine C. and Bloch B. (1995) D1 and D2 dopamine receptor gene expression in the rat striatum: sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAs in distinct neuronal populations of the dorsal and ventral striatum. J. comp. Neurol. 355, 418-426.
38. 38. Le Moine C., Normand E., Guitteny A. F., Fouque B., Teoule R. and Bloch B. (1990) Dopamine receptor gene expression by enkephalin neurons in rat forebrain. Proc. natn. Acad. Sci. U.S.A. 87, 230-234.
39. 39. Letter A. A., Matsuda L. A., Merchant K. M., Gibb J. W. and Hanson G. R. (1987) Characterization of dopaminergic influence on striatal-nigral neurotensin systems. Brain Res. 422, 200-203.
40. 40. Levant B., Merchant K. M., Dorsa D. M. and Nemeroff C. B. (1992) BMY 14802, a potential antipsychotic drug, increases expression of proneurotensin mRNA in the rat striatum. Molec. Brain Res. 12, 279-284.
41. 41. Mansour A., Meador-Woodruff J. H., Bunzow J. R., Civelli O., Akil H. and Watson S. J. (1990) Localization of dopamine D2 receptor mRNA and D1 and D2 receptor binding in the rat brain and pituitary: an in situ hybridization-receptor autoradiographic analysis. J. Neurosci. 10, 2587-2600.
42. 42. Mansour A., Meador-Woodruff J. H., Zhou Q., Civelli O., Akil H. and Watson S. J. (1992) A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques. Neuroscience 46, 959-971.
43. 43. Marksteiner J., Saria A. and Krause J. E. (1992) Comparative distribution of neurokinin B, substance P- and enkephalin-like immunoreactivities and neurokinin B messenger RNA in the basal forebrain of the rat: evidence for neurochemical compartmentation. Neuroscience 51, 107-120.
44. 44. McGeorge A. J. and Faull R. L. M. (1989) The organization of the projection from the cerebral cortex to the striatum in the rat. Neuroscience 29, 503-537.
45. 45. Merchant K. M., Hanson G. R. and Dorsa D. M. (1994) Induction of neurotensin and c-fos mRNA in distinct subregions of rat neostriatum after acute methamphetamine: comparison with acute haloperidol effects. J. Pharmac. exp. Ther. 269, 806-812.
46. 46. Merchant K. M. and Miller M. A. (1994) Coexpression of neurotensin and c-fos mRNAs in rat neostriatal neurons following acute haloperidol. Molec. Brain Res. 23, 271-277.
47. 47. Moyner H., Sprengl R., Schoepfer R., Herb A., Higuchi M., Lomeli H., Burnashev N., Sakmann B. and Seeburg P. H. (1992) Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science 256, 1217-1221.
48. 48. Nakao N., Brundin P., Funa K., Lindvall O. and Odin P. (1995) Trophic and protective actions of brain-derived neurotrophic factor on striatal DARPP-32-containing neurons in vitro. Devl Brain Res. 90, 92-101.
49. 49. Nemeroff C. B. (1980) Neurotensin: perchance an endogenous neuroleptic?. Biol. Psychiat. 15, 283-302.
50. 50. Nicot A., Rostene W. and Berod A. (1994) Neurotensin receptor expression in the rat forebrain and midbrain: a combined analysis by in situ hybridization and receptor autoradiography. J. comp. Neurol. 341, 407-419.
51. 51. Ouimet C. C., Miller P. E., Hemmings H. C., Walaas S. I. and Greengard P. (1984) DARPP-32, a dopamine and adenosine 3′:5′-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization. J. Neurosci. 4, 111-124.
52. 52. Palacios J. M. and Kuhar M. J. (1981) Neurotensin receptors are located on dopamine-containing neurones in rat midbrain. Nature 294, 587-589.
53. 53. Penny G. R., Afsharpour S. and Kitai S. T. (1986) The glutamate decarboxylase-, leucine enkephalin-, methionine enkephalin- and substance P-immunoreactive neurons in the neostriatum of the rat and cat: evidence for partial population overlap. Neuroscience 17, 1011-1045.
54. 54. Petrusz P. and Merchenthaler I. and Maderdrut J. L. (1985) Distribution of enkephalin-containing neurons in the central nervous system. In Handbook of Chemical Neuroanatomy (eds Björklund A. and Hökfelt T.), Vol. 4, pp. 273-319. Elsevier Science B.V, Amsterdam.
55. 55. Pickle V. M., Sumal K. K., Beckley S. C., Miller R. J. and Reis D. J. (1980) Immunocytochemical localization of enkephalin in the neostriatum of rat brain: a light and electron microscopic study. J. comp. Neurol. 189, 721-740.
56. 56. Reiner A. and Anderson K. D. (1990) The patterns of neurotransmitter and neuropeptide co-occurrence among striatal projection neurons: conclusions based on recent findings. Brain Res. 15, 251-265.
57. 57. Sato M., Kiyama H. and Tohyama M. (1992) Different postnatal development of cells expressing mRNA encoding neurotensin receptor. Neuroscience 48, 137-149.
58. 58. Schalling M., Djurfeldt M., Hökfelt T., Ehrlich M., Kurihara T. and Greengard P. (1990) Distribution and cellular localization of DARPP-32 mRNA in rat brain. Molec. Brain Res. 7, 139-149.
59. 59. Senger B., Brog J. S. and Zahm D. S. (1993) Subsets of neurotensin-immunoreactive neurons in the rat striatal complex following antagonism of the dopamine D2 receptor: an immunohistochemical double-labelling study using antibodies against FOS. Neuroscience 57, 649-660.
60. 60. Snyder S. H., Banerjee S. P., Yamamura H. I. and Greenberg D. (1974) Drugs, neurotransmitters and schizophrenia. Science 184, 1243.
61. 61. Snyder G. L., Fisone G. and Greengard P. (1994) Phosphorylation of DARPP-32 is regulated by GABA in rat striatum and substantia nigra. J. Neurochem. 63, 1766-1771.
62. 62. Sugimoto T. and Mizuno N. (1987) Neurotensin in projection neurons of the striatum and nucleus accumbens, with reference to coexistence with enkephalin and GABA: an immunohistochemical study in the cat. J. comp. Neurol. 257, 383-395.
63. 63. Surmeier D. J., Reiner A., Levine M. S. and Ariano M. A. (1993) Are neostriatal dopamine receptors co-localized? Trends Neurosci. 16, 299-305.
64. 64. Tsou K., Snyder G. L. and Greengard P. (1993) Nitric oxide/cGMP pathway stimulates phosphorylation of DARPP-32, a dopamine-regulated and cAMP-regulated phospho-protein, in the substantia nigra. Proc. natn. Acad. Sci. U.S.A. 90, 3462-3465.
65. 65. Walaas S. I. and Greengard P. (1984) DARPP-32, a dopamine and adenosine 3′:5′-mono-phosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Regional and cellular distribution in the rat brain. J. Neurosci. 4, 84-98.
66. 66. Yamada M., Yamada M. and Richelson E. (1995) Heterogeneity of melanized neurons expressing neurotensin receptor messenger RNA in the substantia nigra and the nucleus paranigralis of control and Parkinson's disease brain. Neuroscience 64, 405-417.
67. 67. Yoshikawa K., Williams C. and Sabol S. L. (1984) Rat brain enkephalin mRNA. J. biol. Chem. 259, 14301-14308.
68. 68. Young W. S., Bonner T. I. and Brann M. R. (1986) Mesencephalic dopamine neurones regulate the expression of neuropeptide mRNAs in the rat forebrain. Proc. natn. Acad. Sci. U.S.A. 83, 9827-9831.
69. 69. Yung K. K. L., Bolam J. P., Smith A. D., Hersch S. M., Ciliax B. J. and Levey A. I. (1995) Immunocytochemical localization of D1 and D2 dopamine receptors in the basal ganglia of the rat: light and electron microscopy. Neuroscience 65, 709-730.