Facile syntheses of α-bromo-α-silyl ketones and α-bromoacylsilanes from tert-butyldimethylsilyldibromomethane and carbonyl compounds

Tetrahedron

Volumn 52, Issue 46, 1996, Pages 14533-14542

  Shinokubo, Hiroshi ^a   Oshima, Koichiro ^a   Utimoto, Kiitiro ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

KETONE; ORGANOBROMINE DERIVATIVE; SILANE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030580396     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4020(96)00898-8     Document Type: Article

References (42)

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38. 2 also gave only (E)-10d in 90 % yield. The exclusive formation of (E)-isomer might be attributed to the isomerization of (Z)-isomer into (E)-isomer under the acidic reaction conditions.
39. 14
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42. 15. Butyllithium was not so effective as sec-BuLi for the formation of enolate in one-pot procedure.