Inhibition of purified soluble guanylyl cyclase by copper ions

Biochemical Pharmacology

Volumn 52, Issue 7, 1996, Pages 1041-1045

  Schrammel, Astrid ^a   Koesling, Doris ^b   Gorren, Antonius C F ^a   Chevion, Mordechai ^c   Schmidt, Kurt ^a   Mayer, Bernd ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Cu(I) ions; cuprizone; CuSO4 induced enzyme inhibition; glutathione; neocuproine; soluble guanylyl cyclase

Indexed keywords

2,2 DIETHYL 1 NITROSO OXYHYDRAZINE; 2,9 DIMETHYL 1,10 PHENANTHROLINE; CHELATING AGENT; COPPER ION; COPPER SULFATE; CUPRIZONE; CYCLIC GMP; ENZYME ACTIVATOR; GLUTATHIONE; GUANYLATE CYCLASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CATALYSIS; CATTLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME PURIFICATION; LUNG; NONHUMAN; PRIORITY JOURNAL; SOLUBILITY;

EID: 0030580091     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00425-X     Document Type: Article

References (30)

1. 1. Waldman S and Murad F, Cyclic GMP synthesis and function. Pharmacol Rev 39: 163-195, 1987.
2. 2. Ignarro LJ, Heme-dependent activation of guanylate cyclase by nitric oxide: a novel signal transduction mechanism. Blood Vess 28: 67-73, 1991.
3. 3. Moncada S, Palmer RMJ and Higgs EA, Nitric oxide -physiology, pathophysiology, and pharmacology. Pharmacol Rev 43: 109-142, 1991.
4. 4. Garthwaite J and Boulton CL, Nitric oxide signaling in the central nervous system. Annu Rev Physiol 57: 683-706, 1995.
5. 5. Bruckdorfer KR, Jacobs M and Rice-Evans C, Endothelium-derived relaxing factor (nitric oxide), lipoprotein oxidation and atherosclerosis. Biochem Soc Transactions 18: 1061-1063, 1990.
6. 6. Coyle JT and Puttfarcken P, Oxidative stress, glutamate, and neurodegenerative disorders. Science 262: 689-695, 1993.
7. 7. Lefer AM and Lefer DJ, Pharmacology of the endothelium in ischemia-reperfusion and circulatory shock. Annu Rev Pharmacol Toxicol 33: 71-90, 1993.
8. 8. Koesling D, Böhme E and Schultz G, Guanylyl cyclases, a growing family of signal transducing enzymes. FASEB J 5: 2785-2791, 1991.
9. 9. Schulz S, Yuen PST and Garbers DL, The expanding family of guanylyl cyclases. Trends Pharmacol Sci 12: 116-120, 1991.
10. 10. Gerzer R, Böhme E, Hofmann F and Schultz G, Soluble guanylate cyclase purified from bovine lung contains heme and copper. FEBS Lett 132: 71-74, 1981.
11. 11. Wedel B, Humbert P, Harteneck C, Foerster J, Malkewitz J, Böhme E, Schultz G and Koesling D, Mutation of His-105 of the β1-subunit yields a nitric oxide-insensitive form of soluble guanylyl cyclase. Proc Natl Acad Sci USA 91: 2592-2596, 1994.
12. 12. Traylor TG and Sharma VS, Why NO. Biochemistry 31: 2847-2849, 1992.
13. 13. Rifkind JM, Copper and the oxidation of hemoglobins. In: Metal Ions in Biological Systems, Vol. 12 (Ed. Sigel H), pp. 191-232. Marcel Dekker, New York, 1981.
14. 14. Smith RC, Reed VD and Webb TR. Reversal of copper(II)-induced methemoglobin formation by thiols. J Inorg Biochem 52: 173-182, 1993.
15. 15. Humbert P, Niroomand F, Fischer G, Mayer B, Koesling D, Hinsch K-D, Gausepohl H, Frank R, Schultz G and Böhme E, Purification of soluble guanylyl cyclase from bovine lung by a new immunoaffinity chromatographic method. Eur J Biochem 190: 273-278, 1990.
16. 16. Maragos CM, Morley D, Wink DA, Dunams TM, Saavedra JE, Hoffman A, Bove AA, Isaac L, Hrabie JA and Keefer LK, Complexes of NO with nucleophiles as agents for the controlled biological release of nitric oxide-vasorelaxant effects. J Med Chem 34: 3242-3247, 1991.
17. 17. Schultz G and Böhme E, Guanylate cyclase. GTP pyrophosphate-lyase (cyclizing), E.C.4.6.1.2. In: Methods of Enzymatic Analysis, Vol. 4 (Eds. Bergmeyer HU, Bergmeyer J and GraßI M), pp. 379-389. Verlag Chemie, Weinheim, Germany, 1984.
18. 18. Mayer B, Klatt P, Werner ER and Schmidt K, Kinetics and mechanism of tetrahydrobiopterin-induced oxidation of nitric oxide. J Biol Chem 270: 655-659, 1995.
19. 19. Bradford MM, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
20. 20. Spear N and Aust SD, Hydroxylation of deoxyguanosine in DNA by copper and thiols. Arch Biochem Biophys 317: 142-148, 1995.
21. 21. Gordge MP, Meyer DJ, Hothersall J, Neild GH, Payne NN and Noron-Hadutra A, Copper chelation-induced reduction of the biological activity of S-nitrosothiols. Br J Pharmacol 114: 1083-1089, 1995.
22. 22. Mayer B, Brunner F and Schmidt K, Inhibition of nitric oxide synthesis by methylene blue. Biochem Pharmacol 45: 367-374, 1993.
23. 23. Garthwaite J, Southam E, Boulton CL, Nielsen EB, Schmidt K and Mayer B, Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo-[4,3-a]quinoxalin-1-one. Mol Pharmacol 48: 184-188, 1995.
24. 24. Schrammel A, Behrends S, Schmidt K, Koesling D and Mayer B, Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase. Mol Pharmacol 50: 1-5, 1996.
25. 25. Gorren ACF, Schrammel A, Schmidt K and Mayer B, Decomposition of S-nitrosoglutathione in the presence of copper ions and glutathione. Arch Biochem Biophys 330: 219-228, 1996.
26. 26. Tietze F, Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione. Anal Biochem 27: 502-522, 1969.
27. 27. Chevion M, Jiang YD, Harel R, Berenshtein E, Uretzky G and Kitrossky N, Copper and iron are mobilized following myocardial ischemia - possible predictive criteria for tissue injury. Proc Natl Acad Sci USA 90: 1102-1106, 1993.
28. 28. Bray TM and Taylor CG, Tissue glutathione, nutrition, and oxidative stress. Can J Physiol Pharmacol 71: 746-751, 1993.
29. 29. Beckmann JS, Ye YZ, Anderson PG, Chen J, Accavitti MA, Tarpey MM and White CR, Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry. Biol Chem Hoppe Seyler 375: 81-88, 1994.
30. 30. Swain JA, Darley-Usmar V and Gutteridge JMC, Peroxynitrite releases copper from caeruloplasmin - implications for atherosclerosis. FEBS Lett 342: 49-52, 1994.