메뉴 건너뛰기




Volumn 262, Issue 5, 1996, Pages 640-651

Human immunodeficiency virus (HIV) Nef is an RNA binding protein in cell-free systems

Author keywords

HIV; Nef; RNA binding protein

Indexed keywords

ARGININE; BLOOD CLOTTING FACTOR 10A; GENE PRODUCT; GLYCINE; HYBRID PROTEIN; MALTOSE BINDING PROTEIN; RNA BINDING PROTEIN; VIRUS PROTEIN;

EID: 0030580056     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0542     Document Type: Article
Times cited : (9)

References (81)
  • 1
    • 0023790222 scopus 로고
    • Nef protein of HIV-1 is a transcriptional represser of HIV-1 LTR
    • Ahmad, N. & Venkatesan, S. (1988). Nef protein of HIV-1 is a transcriptional represser of HIV-1 LTR. Science, 241, 1481-1485.
    • (1988) Science , vol.241 , pp. 1481-1485
    • Ahmad, N.1    Venkatesan, S.2
  • 2
    • 0029015330 scopus 로고
    • Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis
    • Aiken, C. & Trono, D. (1995). Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis. J. Virol. 69, 5048-5056.
    • (1995) J. Virol. , vol.69 , pp. 5048-5056
    • Aiken, C.1    Trono, D.2
  • 3
    • 0028180868 scopus 로고
    • Nef induces CD4 endocytosis: Requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain
    • Aiken, C., Konner, J., Landau, N. R., Lenburg, M. E. & Trono, D. (1994). Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell, 76, 853-864.
    • (1994) Cell , vol.76 , pp. 853-864
    • Aiken, C.1    Konner, J.2    Landau, N.R.3    Lenburg, M.E.4    Trono, D.5
  • 4
    • 0028812170 scopus 로고
    • Induction of membrane proliferation by poliovirus proteins 2C and 2BC
    • Aldabe, R. & Carrasco, L. (1995). Induction of membrane proliferation by poliovirus proteins 2C and 2BC. Biochem. Biophys. Res. Commun. 206, 64-76.
    • (1995) Biochem. Biophys. Res. Commun. , vol.206 , pp. 64-76
    • Aldabe, R.1    Carrasco, L.2
  • 6
    • 0025353408 scopus 로고
    • Constitutive expression of human immunodeficiency virus (HIV) nef protein in human astrocytes does not influence basal or induced HIV long terminal repeat activity
    • Bachelerie, F., Alcamí, J., Hazan, U., Israël, N., Goud, B., Arenzana-Seisdedos, F. & Virelizier, J.-L. (1990). Constitutive expression of human immunodeficiency virus (HIV) nef protein in human astrocytes does not influence basal or induced HIV long terminal repeat activity. J. Virol. 64, 3059-3062.
    • (1990) J. Virol. , vol.64 , pp. 3059-3062
    • Bachelerie, F.1    Alcamí, J.2    Hazan, U.3    Israël, N.4    Goud, B.5    Arenzana-Seisdedos, F.6    Virelizier, J.-L.7
  • 7
    • 0026344316 scopus 로고
    • The HIV-1 nef protein does not have guanine nucleotide binding, GTPase, or autophosphorylating activities
    • Backer, J. M., Mendola, C. E., Fairhurst, J. L. & Kovesdi, I. (1991). The HIV-1 nef protein does not have guanine nucleotide binding, GTPase, or autophosphorylating activities. AIDS Res. Hum. Retroviruses, 7, 1015-1020.
    • (1991) AIDS Res. Hum. Retroviruses , vol.7 , pp. 1015-1020
    • Backer, J.M.1    Mendola, C.E.2    Fairhurst, J.L.3    Kovesdi, I.4
  • 8
    • 0028355604 scopus 로고
    • Human immunodeficiency virus type 1 Nef protein down-regulates transcription factors NF-kappaB and AP-1 in human T cells in vitro after T-cell receptor stimulation
    • Bandres, J. C. & Ratner, L. (1994). Human immunodeficiency virus type 1 Nef protein down-regulates transcription factors NF-kappaB and AP-1 in human T cells in vitro after T-cell receptor stimulation. J. Virol. 68, 3243-3249.
    • (1994) J. Virol. , vol.68 , pp. 3243-3249
    • Bandres, J.C.1    Ratner, L.2
  • 9
    • 0029036230 scopus 로고
    • A human virus protein, poliovirus protein 2BC, induces membrane proliferation and blocks the exocytic pathway in the yeast Saccharomyces cerevisiae
    • Barco, A. & Carrasco, L. (1995). A human virus protein, poliovirus protein 2BC, induces membrane proliferation and blocks the exocytic pathway in the yeast Saccharomyces cerevisiae. EMBO J. 14, 3349-3364.
    • (1995) EMBO J. , vol.14 , pp. 3349-3364
    • Barco, A.1    Carrasco, L.2
  • 10
    • 0028062729 scopus 로고
    • Physical interaction of the HIV-1 Nef protein with β-COP, a component of non-clathrin-coated vesicles essential for membrane traffic
    • Benichou, S., Bomsel, M., Bodéus, M., Durand, H., Douté, M., Letourneur, F., Camonis, J. & Benarous, R. (1994). Physical interaction of the HIV-1 Nef protein with β-COP, a component of non-clathrin-coated vesicles essential for membrane traffic. J. Biol. Chem. 269, 30073-30076.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30073-30076
    • Benichou, S.1    Bomsel, M.2    Bodéus, M.3    Durand, H.4    Douté, M.5    Letourneur, F.6    Camonis, J.7    Benarous, R.8
  • 11
    • 0027158904 scopus 로고
    • Downregulation of cell surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection
    • Benson, R. E., Sanfridson, A., Ottinger, J. S., Doyle, C. & Cullen, B. R. (1993). Downregulation of cell surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection. J. Exp. Med. 177, 1561-1566.
    • (1993) J. Exp. Med. , vol.177 , pp. 1561-1566
    • Benson, R.E.1    Sanfridson, A.2    Ottinger, J.S.3    Doyle, C.4    Cullen, B.R.5
  • 12
    • 0028326761 scopus 로고
    • New insights into the auxiliary domains of eukaryotic RNA binding proteins
    • Biamonti, G. & Riva, S. (1994). New insights into the auxiliary domains of eukaryotic RNA binding proteins. FEBS Letters, 340, 1-8.
    • (1994) FEBS Letters , vol.340 , pp. 1-8
    • Biamonti, G.1    Riva, S.2
  • 13
    • 0023415083 scopus 로고
    • Association of polioviral proteins of the P2 genomic region with the viral replication complex and virus-induced membrane synthesis as visualized by electron microscopic immunocytochemistry and autoradiography
    • Bienz, K., Egger, D. & Pasamontes, L. (1987). Association of polioviral proteins of the P2 genomic region with the viral replication complex and virus-induced membrane synthesis as visualized by electron microscopic immunocytochemistry and autoradiography. Virology, 160, 220-226.
    • (1987) Virology , vol.160 , pp. 220-226
    • Bienz, K.1    Egger, D.2    Pasamontes, L.3
  • 14
    • 0026519212 scopus 로고
    • Structural and functional characterization of the poliovirus replication complex
    • Bienz, K., Egger, D., Pfister, T. & Troxler, M. (1992). Structural and functional characterization of the poliovirus replication complex. J. Virol. 66, 2740-2747.
    • (1992) J. Virol. , vol.66 , pp. 2740-2747
    • Bienz, K.1    Egger, D.2    Pfister, T.3    Troxler, M.4
  • 15
    • 0025998490 scopus 로고
    • Mutational analysis of the simian immunodeficiency virus SIV mac nef gene
    • Binninger, D., Ennen, J., Bonn, D., Norley, S. G. & Kurth, R. (1991). Mutational analysis of the simian immunodeficiency virus SIV mac nef gene. J. Virol. 65, 5237-5243.
    • (1991) J. Virol. , vol.65 , pp. 5237-5243
    • Binninger, D.1    Ennen, J.2    Bonn, D.3    Norley, S.G.4    Kurth, R.5
  • 16
    • 0028129989 scopus 로고
    • Conserved structures and diversity of functions of RNA-binding proteins
    • Burd, C. G. & Dreyfuss, G. (1994). Conserved structures and diversity of functions of RNA-binding proteins. Science, 265, 615-621.
    • (1994) Science , vol.265 , pp. 615-621
    • Burd, C.G.1    Dreyfuss, G.2
  • 17
    • 0027275863 scopus 로고
    • RNA-binding patterns in total human tissue proteins: Analysis by northwestern blotting
    • Chen, X., Sadlock, J. & Schon, E. A. (1993). RNA-binding patterns in total human tissue proteins: analysis by northwestern blotting. Biochem. Biophys. Res. Commun. 191, 18-25.
    • (1993) Biochem. Biophys. Res. Commun. , vol.191 , pp. 18-25
    • Chen, X.1    Sadlock, J.2    Schon, E.A.3
  • 19
    • 0024829082 scopus 로고
    • Differential effects of nef on HIV replication: Implications for viral pathogenesis in the host
    • Cheng-Mayer, C., Iannello, P., Shaw, K., Luciw, P. A. & Levy, J. A. (1989). Differential effects of nef on HIV replication: implications for viral pathogenesis in the host. Science, 246, 1629-1632.
    • (1989) Science , vol.246 , pp. 1629-1632
    • Cheng-Mayer, C.1    Iannello, P.2    Shaw, K.3    Luciw, P.A.4    Levy, J.A.5
  • 20
    • 0028037893 scopus 로고
    • Membrane rearrangement and vesicle induction by recombinant poliovirus 2C and 2BC in human cells
    • Cho, M. W., Teterina, N., Egger, D., Bienz, K. & Ehrenfeld, E. (1994). Membrane rearrangement and vesicle induction by recombinant poliovirus 2C and 2BC in human cells. Virology, 202, 129-145.
    • (1994) Virology , vol.202 , pp. 129-145
    • Cho, M.W.1    Teterina, N.2    Egger, D.3    Bienz, K.4    Ehrenfeld, E.5
  • 21
    • 0028302998 scopus 로고
    • Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene
    • Chowers, M. Y., Spina, C. A., Kwoh, T. J., Fitch, N. J. S., Richman, D. D. & Guatelli, J. C. (1994). Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene. J. Virol. 68, 2906-2914.
    • (1994) J. Virol. , vol.68 , pp. 2906-2914
    • Chowers, M.Y.1    Spina, C.A.2    Kwoh, T.J.3    Fitch, N.J.S.4    Richman, D.D.5    Guatelli, J.C.6
  • 22
    • 0028820530 scopus 로고
    • The growth advantage conferred by HIV-1 nef is determined at the level of viral DNA formation and is independent of CD4 downregulation
    • Chowers, M. Y., Pandor, M. W., Spina, C. A., Richman, D. D. & Guatelli, J. C. (1995). The growth advantage conferred by HIV-1 nef is determined at the level of viral DNA formation and is independent of CD4 downregulation. Virology, 212, 451-457.
    • (1995) Virology , vol.212 , pp. 451-457
    • Chowers, M.Y.1    Pandor, M.W.2    Spina, C.A.3    Richman, D.D.4    Guatelli, J.C.5
  • 23
    • 0026842469 scopus 로고
    • Visualization and characterization of tobacco mosaic virus movement protein binding to single-stranded nucleic acids
    • Citovsky, V., Wong, M. L., Shaw, A. L., Prasad, B. V. & Zambryski, P. (1992). Visualization and characterization of tobacco mosaic virus movement protein binding to single-stranded nucleic acids. Plant Cell, 4, 397-411.
    • (1992) Plant Cell , vol.4 , pp. 397-411
    • Citovsky, V.1    Wong, M.L.2    Shaw, A.L.3    Prasad, B.V.4    Zambryski, P.5
  • 24
    • 0028173343 scopus 로고
    • The role of Nef in the replication cycle of the human and simian immunodeficiency viruses
    • Cullen, B. R. (1994). The role of Nef in the replication cycle of the human and simian immunodeficiency viruses. Virology, 205, 1-6.
    • (1994) Virology , vol.205 , pp. 1-6
    • Cullen, B.R.1
  • 25
    • 0027043276 scopus 로고
    • Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene
    • Daniel, M. D., Kirchhoff, F., Czajak, C., Sehgal, P. K. & Desrosiers, R. C. (1992). Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science, 258, 1938-1941.
    • (1992) Science , vol.258 , pp. 1938-1941
    • Daniel, M.D.1    Kirchhoff, F.2    Czajak, C.3    Sehgal, P.K.4    Desrosiers, R.C.5
  • 26
    • 0026717493 scopus 로고
    • Natural HIV-1 Nef accelerates virus replication in primary human lymphocytes
    • De Ronde, A., Klaver, B., Keulen, W., Smit, L. & Goudsmit, J. (1992). Natural HIV-1 Nef accelerates virus replication in primary human lymphocytes. Virology, 188, 391-395.
    • (1992) Virology , vol.188 , pp. 391-395
    • De Ronde, A.1    Klaver, B.2    Keulen, W.3    Smit, L.4    Goudsmit, J.5
  • 27
    • 0028918959 scopus 로고
    • Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A
    • Doedens, J. R. & Kirkegaard, K. (1995). Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A. EMBO J. 14, 894-907.
    • (1995) EMBO J. , vol.14 , pp. 894-907
    • Doedens, J.R.1    Kirkegaard, K.2
  • 29
    • 0022860568 scopus 로고
    • Cytoplasmic localization of the HTLV-III 3' orf protein in cultured T cells
    • Franchini, G., Robert-Guroff, M., Ghrayeb, J., Chang, N. T. & Wong-Staal, F. (1986). Cytoplasmic localization of the HTLV-III 3' orf protein in cultured T cells. Virology, 155, 593-599.
    • (1986) Virology , vol.155 , pp. 593-599
    • Franchini, G.1    Robert-Guroff, M.2    Ghrayeb, J.3    Chang, N.T.4    Wong-Staal, F.5
  • 30
    • 0025733252 scopus 로고
    • Serine phosphorylation-independent downregulation of cell-surface CD4 by nef
    • Garcia, J. V. & Miller, A. D. (1991). Serine phosphorylation-independent downregulation of cell-surface CD4 by nef. Nature, 350, 508-511.
    • (1991) Nature , vol.350 , pp. 508-511
    • Garcia, J.V.1    Miller, A.D.2
  • 31
    • 0027450321 scopus 로고
    • The negative effect of human immunodefiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4
    • Garcia, J. V., Alfano, J. & Miller, A. D. (1993). The negative effect of human immunodefiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4. J. Virol. 67, 1511-1516.
    • (1993) J. Virol. , vol.67 , pp. 1511-1516
    • Garcia, J.V.1    Alfano, J.2    Miller, A.D.3
  • 32
    • 0029046227 scopus 로고
    • Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef
    • Goldsmith, M. A., Warmerdam, M. T., Atchison, R. E., Miller, M. D. & Greene, W. C. (1995). Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef. J. Virol. 69, 4112-4121.
    • (1995) J. Virol. , vol.69 , pp. 4112-4121
    • Goldsmith, M.A.1    Warmerdam, M.T.2    Atchison, R.E.3    Miller, M.D.4    Greene, W.C.5
  • 33
  • 34
    • 0021171129 scopus 로고
    • Molecular cloning and characterization of the HTLV-III virus associated with AIDS
    • Hahn, B. H., Shaw, G. M., Arya, S. K., Popovic, M., Gallo, R. C. & Wong-Staal, F. (1984). Molecular cloning and characterization of the HTLV-III virus associated with AIDS. Nature, 312, 166-169.
    • (1984) Nature , vol.312 , pp. 166-169
    • Hahn, B.H.1    Shaw, G.M.2    Arya, S.K.3    Popovic, M.4    Gallo, R.C.5    Wong-Staal, F.6
  • 35
    • 0024331985 scopus 로고
    • Nef protein of human immunodeficiency virus type 1: Evidence against its role as a transcriptional inhibitor
    • Hammes, S. R., Dixon, E. P., Malim, M. H., Cullen, B. R. & Greene, W. C. (1989). Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor. Proc. Natl Acad. Sci. USA, 86, 9549-9553.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 9549-9553
    • Hammes, S.R.1    Dixon, E.P.2    Malim, M.H.3    Cullen, B.R.4    Greene, W.C.5
  • 36
    • 0026974913 scopus 로고
    • In vivo derived HIV-1 nef gene products are heterogeneous and lack detectable nucleotide binding activity
    • Harris, M., Hislop, S., Patsilinacos, P. & Neil, J. C. (1992). In vivo derived HIV-1 nef gene products are heterogeneous and lack detectable nucleotide binding activity. AIDS Res. Hum. Retroviruses, 8, 537-543.
    • (1992) AIDS Res. Hum. Retroviruses , vol.8 , pp. 537-543
    • Harris, M.1    Hislop, S.2    Patsilinacos, P.3    Neil, J.C.4
  • 37
    • 0028908766 scopus 로고
    • Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection
    • Huang, Y., Zhang, L. & Ho, D. D. (1995). Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection. J. Virol. 69, 93-100.
    • (1995) J. Virol. , vol.69 , pp. 93-100
    • Huang, Y.1    Zhang, L.2    Ho, D.D.3
  • 39
    • 0025962006 scopus 로고
    • Genetic characterization of human immunodeficiency virus type 1 nef gene products translated in vitro and expressed in mammalian cells
    • Kaminchik, J., Bashan, N., Itach, A., Sarver, N., Gorecki, M. & Panet, A. (1991). Genetic characterization of human immunodeficiency virus type 1 nef gene products translated in vitro and expressed in mammalian cells. J. Virol. 65, 583-588.
    • (1991) J. Virol. , vol.65 , pp. 583-588
    • Kaminchik, J.1    Bashan, N.2    Itach, A.3    Sarver, N.4    Gorecki, M.5    Panet, A.6
  • 40
    • 0028018287 scopus 로고
    • Cellular distribution of HIV type 1 Nef protein: Identification of domains in Nef required for association with membrane and detergent-insoluble cellular matrix
    • Kaminchik, J., Margalit, R., Yaish, S., Drummer, H., Amit, B., Sarver, N., Gorecki, M. & Panet, A. (1994). Cellular distribution of HIV type 1 Nef protein: identification of domains in Nef required for association with membrane and detergent-insoluble cellular matrix. AIDS Res. Hum. Retroviruses, 10, 1003-1010.
    • (1994) AIDS Res. Hum. Retroviruses , vol.10 , pp. 1003-1010
    • Kaminchik, J.1    Margalit, R.2    Yaish, S.3    Drummer, H.4    Amit, B.5    Sarver, N.6    Gorecki, M.7    Panet, A.8
  • 41
  • 42
    • 0026740718 scopus 로고
    • Primary structure and binding activity of the hnRNP U protein: Binding RNA through RGG box
    • Kiledjian, M. & Dreyfuss, G. (1992). Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box. EMBO J. 11, 2655-2664.
    • (1992) EMBO J. , vol.11 , pp. 2655-2664
    • Kiledjian, M.1    Dreyfuss, G.2
  • 43
    • 0024316873 scopus 로고
    • Lack of a negative influence on viral growth by the nef gene of human immunodeficiency virus type 1
    • Kim, S., Ikeuchi, K., Byrn, R., Groopman, J. & Baltimore, D. (1989). Lack of a negative influence on viral growth by the nef gene of human immunodeficiency virus type 1. Proc. Natl Acad. Sci. USA, 86, 9544-9548.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 9544-9548
    • Kim, S.1    Ikeuchi, K.2    Byrn, R.3    Groopman, J.4    Baltimore, D.5
  • 45
    • 0023648812 scopus 로고
    • Cloning of HTLV-4 and its relation to simian and human immunodefiency viruses
    • Kornfeld, H., Riedel, N., Viglianti, G. A., Hirsch, V. & Mullins, J. J. (1987). Cloning of HTLV-4 and its relation to simian and human immunodefiency viruses. Nature, 326, 610-613.
    • (1987) Nature , vol.326 , pp. 610-613
    • Kornfeld, H.1    Riedel, N.2    Viglianti, G.A.3    Hirsch, V.4    Mullins, J.J.5
  • 46
    • 0025685476 scopus 로고
    • RNA helicase: A novel activity associated with a protein encoded by a positive strand RNA virus
    • Lain, S., Riechmann, J. L. & García, J. A. (1991). RNA helicase: a novel activity associated with a protein encoded by a positive strand RNA virus. Nucl. Acids Res. 18, 7003-7006.
    • (1991) Nucl. Acids Res. , vol.18 , pp. 7003-7006
    • Lain, S.1    Riechmann, J.L.2    García, J.A.3
  • 47
    • 0024434420 scopus 로고
    • Sequence-specific recognition of RNA hairpins by bacteriophage antiterminators requires a conserved arginine-rich motif
    • Lazinski, D., Grzadzielska, E. & Das, A. (1989). Sequence-specific recognition of RNA hairpins by bacteriophage antiterminators requires a conserved arginine-rich motif. Cell, 59, 207-218.
    • (1989) Cell , vol.59 , pp. 207-218
    • Lazinski, D.1    Grzadzielska, E.2    Das, A.3
  • 48
    • 0027531918 scopus 로고
    • Pathogenesis of human immunodeficiency virus infection
    • Levy, J. A. (1993). Pathogenesis of human immunodeficiency virus infection. Microbiol. Rev. 57, 183-289.
    • (1993) Microbiol. Rev. , vol.57 , pp. 183-289
    • Levy, J.A.1
  • 49
    • 0025213458 scopus 로고
    • An intragenic revertant of a poliovirus 2C mutant has an uncoating defect
    • Li, J. P. & Baltimore, D. (1990). An intragenic revertant of a poliovirus 2C mutant has an uncoating defect. J. Virol. 64, 1102-1107.
    • (1990) J. Virol. , vol.64 , pp. 1102-1107
    • Li, J.P.1    Baltimore, D.2
  • 50
    • 0024318345 scopus 로고
    • Effects of long terminal repeat mutations on human immunodeficiency virus type 1 replication
    • Lu, Y., Stenzel, M., Sodroski, J. G. & Haseltine, W. A. (1989). Effects of long terminal repeat mutations on human immunodeficiency virus type 1 replication. J. Virol. 63, 4115-4119.
    • (1989) J. Virol. , vol.63 , pp. 4115-4119
    • Lu, Y.1    Stenzel, M.2    Sodroski, J.G.3    Haseltine, W.A.4
  • 51
    • 0025941876 scopus 로고
    • Binding of human immunodeficiency virus type 1 (HIV-1) RNA to recombinant HIV-1 gag polyprotein
    • Luban, J. & Goff, S. P. (1991). Binding of human immunodeficiency virus type 1 (HIV-1) RNA to recombinant HIV-1 gag polyprotein. J. Virol. 65, 3203-3212.
    • (1991) J. Virol. , vol.65 , pp. 3203-3212
    • Luban, J.1    Goff, S.P.2
  • 52
    • 0009524520 scopus 로고
    • Mutational analysis of the human immunodeficiency virus: The orf-B region down-regulates virus replication
    • Luciw, P. A., Cheng, Mayer, C. & Levy, J. A. (1987). Mutational analysis of the human immunodeficiency virus: the orf-B region down-regulates virus replication. Proc. Natl Acad. Sci. USA, 84, 1434-1438.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 1434-1438
    • Luciw, P.A.1    Cheng, M.C.2    Levy, J.A.3
  • 53
    • 0026047554 scopus 로고
    • Purification and characterization of human immunodeficiency virus type 1 nef gene product expressed by a recombinant baculovirus
    • Matsuura, Y., Maekawa, M., Hattori, S., Ikegami, N., Hayashi, A., Yamazaki, S., Morita, C. & Takebe, Y. (1991). Purification and characterization of human immunodeficiency virus type 1 nef gene product expressed by a recombinant baculovirus. Virology, 184, 580-586.
    • (1991) Virology , vol.184 , pp. 580-586
    • Matsuura, Y.1    Maekawa, M.2    Hattori, S.3    Ikegami, N.4    Hayashi, A.5    Yamazaki, S.6    Morita, C.7    Takebe, Y.8
  • 54
    • 0028006247 scopus 로고
    • The human immunodeficiency virus-1 nef gene product: A positive factor for viral infection and replication in primary lymphocytes and macrophages
    • Miller, M. D., Warmerdam, M. T., Gaston, I., Greene, W. C. & Feinberg, M. B. (1994). The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. J. Exp. Med. 179, 101-113.
    • (1994) J. Exp. Med. , vol.179 , pp. 101-113
    • Miller, M.D.1    Warmerdam, M.T.2    Gaston, I.3    Greene, W.C.4    Feinberg, M.B.5
  • 55
    • 0028936207 scopus 로고
    • Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry
    • Miller, M. D., Warmerdam, M. T., Page, K. A., Feinberg, M. B. & Greene, W. C. (1995). Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry. J. Virol. 69, 579-584.
    • (1995) J. Virol. , vol.69 , pp. 579-584
    • Miller, M.D.1    Warmerdam, M.T.2    Page, K.A.3    Feinberg, M.B.4    Greene, W.C.5
  • 58
    • 0347497008 scopus 로고
    • Human immunodeficiency virus type 1 negative factor is a transcriptional silencer
    • Niederman, T. M. J., Thielan, B. & Ratner, L. (1989). Human immunodeficiency virus type 1 negative factor is a transcriptional silencer. Proc. Natl Acad. Sci. USA, 86, 1128-1132.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 1128-1132
    • Niederman, T.M.J.1    Thielan, B.2    Ratner, L.3
  • 59
    • 0026583961 scopus 로고
    • Immunological variation and immunohistochemical localization of HIV-1 Nef demonstrated with monoclonal antibodies
    • Ovod, V., Lagerstedt, A., Ranki, A., Gombert, F. O., Spohn, R., Tähtinen, M. & Jung, G. (1992). Immunological variation and immunohistochemical localization of HIV-1 Nef demonstrated with monoclonal antibodies. AIDS, 6, 25-34.
    • (1992) AIDS , vol.6 , pp. 25-34
    • Ovod, V.1    Lagerstedt, A.2    Ranki, A.3    Gombert, F.O.4    Spohn, R.5    Tähtinen, M.6    Jung, G.7
  • 60
    • 0028274131 scopus 로고
    • The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly (A)
    • Qiu, Y. & Krug, R. M. (1994). The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly (A). J. Virol. 68, 2425-2432.
    • (1994) J. Virol. , vol.68 , pp. 2425-2432
    • Qiu, Y.1    Krug, R.M.2
  • 61
    • 0027406422 scopus 로고
    • Molecular biology and pathogenesis of HIV infection
    • Ratner, L. (1993). Molecular biology and pathogenesis of HIV infection. Curr. Opin. Infect. Dis. 6, 181-190.
    • (1993) Curr. Opin. Infect. Dis. , vol.6 , pp. 181-190
    • Ratner, L.1
  • 62
    • 0025281329 scopus 로고
    • Structure and expression of tat-, rev, and nef specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages
    • Robert-Guroff, M., Popovic, M., Gartner, S., Markham, P., Gallo, R. C. & Reitz, M. (1990). Structure and expression of tat-, rev, and nef specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages. J. Virol. 64, 3391-3398.
    • (1990) J. Virol. , vol.64 , pp. 3391-3398
    • Robert-Guroff, M.1    Popovic, M.2    Gartner, S.3    Markham, P.4    Gallo, R.C.5    Reitz, M.6
  • 63
    • 0027537974 scopus 로고
    • Poliovirus protein 2C has ATPase and GTPase activities
    • Rodriguez, P. L. & Carrasco, L. (1993). Poliovirus protein 2C has ATPase and GTPase activities. J. Biol. Chem. 268, 8105-8110.
    • (1993) J. Biol. Chem. , vol.268 , pp. 8105-8110
    • Rodriguez, P.L.1    Carrasco, L.2
  • 64
    • 0028925901 scopus 로고
    • Poliovirus protein 2C contains two regions involved in RNA binding activity
    • Rodriguez, P. & Carrasco, L. (1995a). Poliovirus protein 2C contains two regions involved in RNA binding activity. J. Biol. Chem. 270, 10105-10112.
    • (1995) J. Biol. Chem. , vol.270 , pp. 10105-10112
    • Rodriguez, P.1    Carrasco, L.2
  • 65
    • 0029107830 scopus 로고
    • Improved factor Xa cleavage of fusion proteins containing maltose binding protein
    • Rodriguez, P. L. & Carrasco, L. (1995b). Improved factor Xa cleavage of fusion proteins containing maltose binding protein. Biotechniques, 18, 238-243.
    • (1995) Biotechniques , vol.18 , pp. 238-243
    • Rodriguez, P.L.1    Carrasco, L.2
  • 66
    • 0028143698 scopus 로고
    • Mechanisms of intracellular protein transport
    • Rothman, J. E. (1994). Mechanisms of intracellular protein transport. Nature, 372, 55-63.
    • (1994) Nature , vol.372 , pp. 55-63
    • Rothman, J.E.1
  • 67
    • 0025012428 scopus 로고
    • The 54-kD protein of signal recognition particle contains a methionine-rich RNA binding domain
    • Römisch, K., Webb, J., Lingelbach, K., Gausepohl, H. & Dobberstein, B. (1990). The 54-kD protein of signal recognition particle contains a methionine-rich RNA binding domain. J. Cell Biol. 111, 1793-1802.
    • (1990) J. Cell Biol. , vol.111 , pp. 1793-1802
    • Römisch, K.1    Webb, J.2    Lingelbach, K.3    Gausepohl, H.4    Dobberstein, B.5
  • 69
    • 0025950085 scopus 로고
    • Nef proteins of the human immunodeficiency viruses (HIV-1 and HIV-2) and simian immunodeficiency virus (SIV) are structurally similar to leucine zipper transcriptional activation factors
    • Samuel, K. P., Hodge, D. R., Chen, Y. M. & Papas, T. S. (1991). Nef proteins of the human immunodeficiency viruses (HIV-1 and HIV-2) and simian immunodeficiency virus (SIV) are structurally similar to leucine zipper transcriptional activation factors. AIDS Res. Hum. Retroviruses, 7, 697-706.
    • (1991) AIDS Res. Hum. Retroviruses , vol.7 , pp. 697-706
    • Samuel, K.P.1    Hodge, D.R.2    Chen, Y.M.3    Papas, T.S.4
  • 70
    • 0027968920 scopus 로고
    • The simian immunodeficiency virus Nef protein promotes degradation of CD4 in human T cells
    • Sanfridson, A., Cullen, B. R. & Doyle, C. (1994). The simian immunodeficiency virus Nef protein promotes degradation of CD4 in human T cells. J. Biol. Chem. 269, 3917-3920.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3917-3920
    • Sanfridson, A.1    Cullen, B.R.2    Doyle, C.3
  • 71
    • 0027229242 scopus 로고
    • Reduced cell surface expression of processed human immunodeficiency virus type 1 envelope glycoprotein in the presence of nef
    • Schwartz, O., Rivière, Y., Heard, J.-M. & Danos, O. (1993). Reduced cell surface expression of processed human immunodeficiency virus type 1 envelope glycoprotein in the presence of nef. J. Virol. 67, 3274-3280.
    • (1993) J. Virol. , vol.67 , pp. 3274-3280
    • Schwartz, O.1    Rivière, Y.2    Heard, J.-M.3    Danos, O.4
  • 73
    • 0029045360 scopus 로고
    • Human immunodeficiency virus type 1 Nef increases the efficiency of reverse transcription in the infected cell
    • Schwartz, O., Maréchal, V., Danos, O. & Heard, J.-M. (1995b). Human immunodeficiency virus type 1 Nef increases the efficiency of reverse transcription in the infected cell. J. Virol. 69, 4053-4059.
    • (1995) J. Virol. , vol.69 , pp. 4053-4059
    • Schwartz, O.1    Maréchal, V.2    Danos, O.3    Heard, J.-M.4
  • 75
    • 0029089597 scopus 로고
    • Nucleocytoplasmic transport: Factors and mechanisms
    • Simos, G. & Hurt, E. C. (1995). Nucleocytoplasmic transport: factors and mechanisms. FEBS Letters, 369, 107-112.
    • (1995) FEBS Letters , vol.369 , pp. 107-112
    • Simos, G.1    Hurt, E.C.2
  • 76
    • 0028116642 scopus 로고
    • Molecular biology of the human immunodeficiency virus accessory proteins
    • Subbramanian, R. A. & Cohen, E. A. (1994). Molecular biology of the human immunodeficiency virus accessory proteins. J. Virol. 68, 6831-6835.
    • (1994) J. Virol. , vol.68 , pp. 6831-6835
    • Subbramanian, R.A.1    Cohen, E.A.2
  • 77
    • 0023025035 scopus 로고
    • Effects of mutations within the 3' orf open reading frame region of human T-cell lymphotropic virus type III (HTLV-III/LAV) on replication and cytopathogenicity
    • Terwilliger, E., Sodroski, G., Rosen, C. A. & Haseltine, W. A. (1986). Effects of mutations within the 3' orf open reading frame region of human T-cell lymphotropic virus type III (HTLV-III/LAV) on replication and cytopathogenicity. J. Virol. 60, 754-760.
    • (1986) J. Virol. , vol.60 , pp. 754-760
    • Terwilliger, E.1    Sodroski, G.2    Rosen, C.A.3    Haseltine, W.A.4
  • 78
    • 0029150052 scopus 로고
    • HIV accessory proteins: Leading roles for the supporting cast
    • Trono, D. (1995). HIV accessory proteins: leading roles for the supporting cast. Cell, 82, 189-192.
    • (1995) Cell , vol.82 , pp. 189-192
    • Trono, D.1
  • 80
    • 0001792440 scopus 로고
    • (Fields, B. N. & Knipe, D. M., eds), 2nd edit., Raven Press, Ltd., New York
    • Wong-Staal, F. (1990). Virology (Fields, B. N. & Knipe, D. M., eds), 2nd edit., pp. 1529-1543, Raven Press, Ltd., New York.
    • (1990) Virology , pp. 1529-1543
    • Wong-Staal, F.1
  • 81
    • 0026610156 scopus 로고
    • Effect of myristoylation on p27 nef subcellular distribution and suppression of HIV-LTR transcription
    • Yu, G. & Felsted, R. L. (1992). Effect of myristoylation on p27 nef subcellular distribution and suppression of HIV-LTR transcription. Virology, 187, 46-55.
    • (1992) Virology , vol.187 , pp. 46-55
    • Yu, G.1    Felsted, R.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.