Norepinephrine attenuates serotonin inhibition of pial venous tone

European Journal of Pharmacology

Volumn 313, Issue 1-2, 1996, Pages 97-102

  Ishine, Takaaki ^a   Lee, Tony J F ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

5 HT (5 hydroxytryptamine, serotonin); cAMP; Norepinephrine; Pial vein; Porcine; Rhythmic constriction

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; CLONIDINE; CYCLIC AMP; METHOXAMINE; NORADRENALIN; PERTUSSIS TOXIN; SEROTONIN; YOHIMBINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; SWINE; TECHNIQUE; VEIN; VEIN TONE;

EID: 0030579104     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00506-7     Document Type: Article

References (16)

1. Asada, Y. and T.J.F. Lee, 1992, a 2-Adrenoceptors mediate norepineph-rine constriction of porcine pial veins, Am. J. Physiol. 263, H1907-H1910.
2. 2 receptors, Prog. Phamacol. Clin. Pharmacol. 7, 45.
3. Deliganis, A.V. and S.J. Peroutka, 1991, 5 hydroxytryptamine receptor agonism predicts antimigraine efficacy, Headache 31, 228.
4. Dohlman, H.G., M.G. Caron and R.J. Lefkowitz, 1987, A family of receptors coupled to guanine nucleotide regulatory proteins, Biochemistry 26 (10), 2657.
5. Flavahan, N.A., H. Shimokawa and P.M. Vanhoutte, 1991, Inhibition of endothelium-dependent relaxations by phorbol myristate acetate in canine coronary arteries: role of a pertussis toxin-sensitive G-protein, J. Pharmacol. Exp. Ther. 256, 50.
6. Fleming, W.W., D.P. Westfall, I.S. DeLaLande and L.B. Jellet, 1972, Log-normal distribution of equieffective doses of norepinephrine and acetylcholine in several tissues, J. Pharmacol. Exp. Ther. 181, 339.
7. 1-like receptor in dog isolated saphenous vein, Br. J. Pharmacol. 94, 1123.
8. 1-like receptors mediate pial venous relaxation, in: Neurotransmission and Cerebrovascular Function, eds. J. Seylaz and E.T. Mackenzie (Elsevier) p. 233.
9. Lee, T.J.-F., M. Ueno, N. Sunagane and M.H. Sun, 1994, Serotonin relaxes porcine pial veins, Am. J. Physiol. 266, H1000.
10. 2 receptors, Life Sci. 28, 1015.
11. Saxena, P.R. and M.O. Den Boer, 1991, Pharmacology of antimigraine drugs, J. Neurol. 238, S28.
12. Shimamoto, H., Y. Shimamoto, CY. Kwan and E.E. Daniel, 1994, Amplification of 5-hydroxytryptamine-induced contractile responses via 5-hydroxytryptamine receptors and alpha-adrenoceptors in dog mesenteric artery and vein, J. Pharmacol. Exp. Ther. 268, 779.
13. Shirasaki, Y., P. Kolm, A. Nickols and T.J.F. Lee, 1988, Endothelial regulation of cyclic GMP and vascular responses in hypertension, J. Pharmacol. Exp. Ther. 245, 53.
14. Sumner, M.J. and P.P.A. Humphrey, 1990, Sumatriptan (GR43175) inhibits cyclic-AMP accumulation in dog isolated saphenous vein, Br. J. Pharmacol. 99, 219.
15. 2-like receptor subtype mediates cAMP synthesis in the porcine pial vein, Am. J. Physiol. 268, H1383.
16. 2-adrenoceptor mediated contractions of the porcine isolated palmar lateral vein, Br. J. Pharmacol. 114, 157.