Expression of truncated midkine in human colorectal cancers

Cancer Letters

Volumn 106, Issue 2, 1996, Pages 287-291

  Miyashiro, Isao ^a,b   Kaname, Tadashi ^c   Nakayama, Takahiro ^b   Nakamori, Shoji ^d   Yagyu, Toshio ^e   Monden, Takushi ^b   Kikkawa, Nobuteru ^e   Nishisho, Isamu ^b   Muramatsu, Takashi ^f   Monden, Morito ^b   Akiyama, Tetsu ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

^d OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

^e OSAKA NATIONAL HOSPITAL   (Japan)

^f NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Alternative splicing; Colorectal cancer; Growth factor; Midkine; Reverse transcription polymerase chain reaction; Truncated form

Indexed keywords

GROWTH FACTOR; MIDKINE;

ADULT; AGED; ARTICLE; CANCER SURGERY; CLINICAL ARTICLE; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

EID: 0030578916     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3835(96)04333-9     Document Type: Article

References (23)

1. Aaronson, S.A. (1991) Growth factors and cancer. Science, 254, 1146-1153.
2. Aridome, K., Tsutsui, J., Takao, S., Kadomatsu, K., Ozawa, M., Aikou, T. and Muramatsu, T. (1995) Increased midkine gene expression in human gastrointestinal cancers. Jpn. J. Cancer Res., 86, 655-661.
3. Cross, M. and Dexter, T.M. (1991) Growth factors in development, transformation, and tumorigenesis. Cell, 64, 271-280.
4. Garver, Jr., R.I., Chan, C.S., and Milner P.G. (1993) Reciprocal expression of pleiotrophin and midkine in normal versus malignant lung tissues. Am. J. Respir. Cell Mol. Biol., 9, 463-466.
5. Garver, Jr., R.I., Radford, D.M., Donis Keller, H., Wick, M.R. and Milner, P.G. (1994) Midkine and pleiotrophin expression in normal and malignant breast tissue. Cancer, 74, 1584-1590.
6. Heldin, C.H. and Westermark, B. (1989) Growth factors as transforming proteins. Eur. J. Biochem., 184, 487-496.
7. Kadomatsu, K., Tomomura, M. and Muramatsu, T. (1988) cDNA cloning and sequencing of a new gene intensely expressed in early differentiation stages of embryonal carcinoma cells and in mid-gestation period of mouse embryogenesis. Biochem. Biophys. Res. Commun., 151, 1312-1318.
8. Kaname, T., Kadomatsu, K., Aridome, K., Yamashita, S., Sakamoto, K., Ogawa, M., Muramatsu, T. and Yamamura, K. (1996) The expression of truncated MK in human tumors. Biochem. Biophys. Res. Commun., 219, 256-260.
9. Kaname, T., Kuwano, A., Murano, I., Uehara, K., Muramatsu, T. and Kajii, T. (1993) Midkine gene (MDK), a gene for prenatal differentiation and neuroregulation, maps to band 11p11.2 by fluorescence in situ hybridization. Genomics, 17, 514-515.
10. Kojima, S., Inui, T., Kimura, T., Sakakibara, S., Muramatsu, H., Amanuma, H., Maruta, H. and Muramatsu, T. (1995) Synthetic peptides derived from midkine enhance plasminogen activator activity in bovine aortic endothelial cells. Biochem. Biophys. Res. Commun., 206, 468-473.
11. Matsubara, S., Tomomura, M., Kadomatsu, K. and Muramatsu, T. (1990) Structure of a retinoic acid-responsive gene, MK, which is transiently activated during the differentiation of embryonal carcinoma cells and the midgestation period of mouse embryogenesis. J. Biol. Chem., 265, 9441-9443.
12. Michikawa, M., Kikuchi, S., Muramatsu, H., Muramatsu, T. and Kim, S.U. (1993) Retinoic acid responsive gene product, midkine, has neurotrophic functions for mouse spinal cord and dorsal root ganglion neurons in culture. J. Neurosci. Res., 35, 530-539.
13. Muramatsu, H., Inui, T., Kimura, T., Sakakibara, S., Song, X.J., Maruta, H. and Muramatsu, T. (1994) Localization of heparin-binding, neurite outgrowth and antigenic regions in midkine molecule. Biochem. Biophys. Res. Commun., 203, 1131-1139.
14. Muramatsu, H. and Muramatsu, T. (1991) Purification of recombinant midkine and examination of its biological activities: functional comparison of new heparin binding factors. Biochem. Biophys. Res. Commun., 177, 652-658.
15. Muramatsu, H., Shirahama, H., Yonezawa, S., Maruta, H. and Muramatsu, T. (1993) Midkine, a retinoic acid-inducible growth/differentiation factor: immunochemical evidence for the function and distribution. Dev. Biol., 159, 392-402.
16. Nakagawara, A., Milbrandt, J., Muramatsu, T., Deuel, T.F., Zhao, H., Cnaan, A. and Brodeur, G. (1995) Differential expression of pleiotrophin and midkine in advanced neuroblastomas. Cancer Res., 55, 1792-1797.
17. Nurcombe, V., Fraser, N., Herlaar, E. and Heath, J.K. (1992) MK, a pluripotential embryonic stem cell-derived neuro-regulatory factor. Development, 116, 1175-1183.
18. Satoh, J., Muramatsu, H., Moretto, G., Muramatsu, T., Chang, H.J., Kim, S.T., Cho, J.M. and Kim, S.U. (1993) Midkine that promotes survival of fetal human neurons is produced by fetal human astrocytes in culture. Brain Res Dev. Brain Res., 75, 201-205.
19. Tsutsui, J., Kadomatsu, K., Matsubara, S., Nakagawara, A., Hamanoue, M., Takao, S., Shimazu, H., Ohi, Y. and Muramatsu, T. (1993) A new family of heparin-binding growth/ differentiation factors: increased midkine expression in Wilms' tumor and other human carcinomas Cancer Res., 53, 1281-1285.
20. Tsutsui, J., Uehara, K., Kadomatsu, K., Matsubara, S. and Muramatsu, T. (1991) A new family of heparin-binding factors: strong conservation of midkine (MK) sequences between the human and the mouse. Biochem. Biophys. Res. Commun., 176, 792-797.
21. Uehara, K., Matsubara, S., Kadomatsu, K., Tsutsui, J. and Muramatsu, T. (1992) Genomic structure of human midkine (MK), a retinoic acid-responsive growth/differentiation factor. J. Biochem. (Tokyo), 111, 563-567.
22. Unoki, K., Ohba, N., Arimura, H., Muramatsu, H. and Muramatsu, T. (1994) Rescue of photoreceptors from the damaging effects of constant light by midkine, a retinoic acid-responsive gene product. Invest. Ophthalmol Vis. Sci., 35, 4063-4068.
23. Yoshida, Y., Goto, M., Tsutsui, J., Ozawa, M., Sato, E., Osame, M. and Muramatsu, T. (1995) Midkine is present in the early stage of cerebral infarct. Dev Brain Res., 85, 25-30.