Alternative assay procedures for cytokines and soluble receptors of the IL-6 family

Journal of Immunological Methods

Volumn 195, Issue 1-2, 1996, Pages 153-159

  Oppmann, Birgit ^a   Stoyan, Tanja ^a   Fischer, Martina ^a   Voltz, Nicole ^a   März, Pia ^a   Rose John, Stefan ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Bioassay; Cytokine; Cytokine receptor; ELISA; IL 6; Soluble receptor

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; HAPTOGLOBIN; INTERLEUKIN 6;

ARTICLE; CELL LINE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETIC TRANSFECTION; HEPATOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

EID: 0030576976     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-1759(96)00110-X     Document Type: Article

References (34)

1. Aarden, L.A., De Groot, E.R., Schaap, O.L. and Lansdorp, P.M. (1987) Production of hybridoma growth factor by human monocytes. Eur. J. Immunol. 17, 1411.
2. Andus, T., Geiger, T., Hirano, T., Northoff, H., Ganter, U., Bauer, J., Kishimoto, T. and Heinrich, P.C. (1987) Recombinant human B cell stimulatory factor 2 (BSF-2/IFN-beta 2) regulates beta-fibrinogen and albumin mRNA levels in Fao-9 cells. FEBS Lett. 221, 18.
3. Baumann, H. and Schendel, P. (1991) Interleukin-11 regulates the hepatic expression of the same plasma protein genes as interleukin-6. J. Biol. Chem. 266, 20424.
4. Baumann, H. and Wong, G.G. (1989) Hepatocyte-stimulating factor III shares structural and functional identity with leukemia-inhibitory factor. J. Immunol. 143, 1163.
5. Baumann, H., Won, K.A. and Jahreis, G.P. (1989) Human hepatocyte-stimulating factor-III and interleukin-6 are structurally and immunologically distinct but regulate the production of the same acute phase plasma proteins. J. Biol. Chem. 264, 8046.
6. Boe, A., Canosi, U., Donini, S., Mastrangeli, R., Ythier, A. and Crescenzi, O.S. (1994) Determination of haptoglobin expression in IL-6 treated HepG2 cells by ELISA and by RNA hybridization - Evaluation of a quantitative method to measure IL-6. J. Immunol. Methods 171, 157.
7. Castell, J.V., Gomez-Lechon, M.J., David, M., Andus, T., Geiger, T., Trullenque, R., Fabra, R. and Heinrich, P.C. (1989) Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes. FEBS Lett. 242, 237.
8. Castell, J.V., Gomez-Lechon, M.J., David, M., Fabra, R., Trullenque, R. and Heinrich, P.C. (1990) Acute-phase response of human hepatocytes: regulation of acute-phase protein synthesis by interleukin-6. Hepatology 12, 1179.
9. Davis, S., Aldrich, T.H., Stahl, N., Pan, L., Taga, T., Kishimoto, T., Ip, N.Y. and Yancopoulos, G.D. (1993) LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor. Science 260, 1805.
10. Fontaine, V., Savino, R., Arcone, R., De Witt, L., Brakenhoff, J.P.J., Content, J. and Ciliberto, G. (1993) Involvement of Arg179 in the active site of human IL-6. Eur. J. Biochem. 211, 749.
11. Gabay, C., Silacci, P., Genin, B., Mentha, G., Le Coultre, C. and Guerne, P.A. (1995) Soluble interleukin-6 receptor strongly increases the production of acute phase protein by hepatoma cells but exerts minimal changes on human primary hepatocytes. Eur. J. Immunol. 25, 2378.
12. Gaines Das, R.E. and Poole, S. (1993) Immunological standardization. The international standard for interleukin-6. Evaluation in an international collaborative study. J. Immunol. Methods 160, 147.
13. Gauldie, J., Richards, C., Harnish, D., Lansdorp, P. and Baumann, H. (1987) Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. Proc. Natl. Acad. Sci. USA 84, 7251.
14. Gearing, D.P., Thut, C.J., VandeBos, T., Gimpel, S.D., Delaney, P.B., King, J., Price, V., Cosman, D. and Beckmann, M.P. (1991) Leukemia inhibitory factor receptor is structurally related to the IL-6 signal transducer, gp130. EMBO J. 10, 2839.
15. Hibi, M., Murakami, M., Saito, M., Hirano, T., Taga, T. and Kishimoto, T. (1990) Molecular cloning and expression of an IL-6 signal transducer, gp130. Cell 63, 1149.
16. Hilton, D.J., Hilton, A.A., Raicevic, A., Rakar, S., Harrison-Smith, M., Gough, N.M., Begley, C.G., Metcalf, D., Nicola, N.A. and Willson, T.A. (1994) Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction. EMBO J. 17, 4765.
17. Karasuyama, H. and Melchers, F. (1988) Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors. Eur. J. Immunol. 18, 97.
18. Kushner, I. and Mackiewicz, A. (1993) In: A. Mackiewicz, I. Kushner and H. Baumann (Eds.). Acute Phase Proteins. Molecular Biology, Biochemistry and Clinical Applications. CRC Press, Boca Raton, FL.
19. Mackiewicz, A., Schooltink, H., Heinrich, P.C. and Rose-John, S. (1992) Complex of soluble human IL-6-receptor/IL-6 up-regulates expression of acute phase proteins. J. Immunol. 149, 2021.
20. Marinkovic, S., Jahreis, G.P., Wong, G.G. and Baumann, H. (1989) IL-6 modulates the synthesis of a specific set of acute phase plasma proteins in vivo. J. Immunol. 142, 808.
21. Mire-Sluis, A.R., Gaines-Das, R. and Thorpe, R. (1995) Immunoassays for detecting cytokines: what are they really measuring? J. Immunol. Methods 186, 157.
22. Murakami, M., Hibi, M., Nakagawa, N., Nakagawa, T., Yasukawa, K., Yamanishi, K., Taga, T. and Kishimoto, T. (1993) IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase. Science 260, 1808.
23. Pennica, D., King, K.L., Shaw, K.J., Luis, E., Rullamas, J., Luoh, S.M., Darbonne, W.C., Knutzon, D.S., Yen, R., Chien, K.R., Baker, J.B. and Wood, W.I. (1995a) Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy. Proc. Natl. Acad. Sci. USA 92, 1142.
24. Pennica, D., Shaw, K.J., Swanson, T.A., Moore, M.W., Shelton, D.L., Zioncheck, K.A., Rosenthal, A., Taga, T., Paoni, N.F.and Wood, W.I. (1995b) Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex. J. Biol. Chem. 270, 10915.
25. Peters, M., Roeb, E., Pennica, D., Meyer zum Büschenfelde, K.H. and Rose-John, S. (1995) A new hepatocyte stimulating factor: cardiotrophin-1 (CT-1). FEBS Lett. 372, 177.
26. Ramadori, G., Van Damme, J., Rieder, H. and Meyer zum Büschenfelde, K.H. (1988) Interleukin 6, the third mediator of acute-phase reaction, modulates hepatic protein synthesis in human and mouse. Comparison with interleukin 1 beta and tumor necrosis factor-alpha. Eur. J. Immunol. 18, 1259.
27. Richards, C.D., Brown, T.J., Shoyab, M., Baumann, H. and Gauldie, J. (1992) Recombinant oncostatin M stimulates the production of acute phase proteins in HepG2 cells and rat primary hepatocytes in vitro. J. Immunol. 148, 1731.
28. Salvati, A.L., Lahm, A., Paonessa, G., Ciliberto, G. and Toniatti, C. (1995) Interleukin-6 (IL-6) antagonism by soluble IL-6 receptor alpha mutated in the predicted gp130-binding interface. J. Biol. Chem. 270, 12242.
29. Schiel, X., Rose-John, S., Dufhues, G., Schooltink, H. and Heinrich, P.C. (1990) Microheterogeneity of human interleukin-6 synthezised by transfected NIH/3T3 cells: comparison with human monocytes, fibroblasts, and endothelial cells. Eur. J. Immunol. 20, 883.
30. Schooltink, H., Stoyan, T., Roeb, E., Heinrich, P.C. and Rose-John, S. (1992) Ciliary neurotrophic factor induces acute-phase protein expression in hepatocytes. FEBS Lett. 314, 280.
31. Sugita, T., Totsuka, T., Saito, M., Yamasaki, K., Taga, T., Hirano, T. and Kishimoto, T. (1990) Functional murine interleukin-6 receptor with the intracisternal A particle gene product at its cytoplasmic domain. Its possible role in plasmacytomagenesis. J. Exp. Med. 171, 2001.
32. Taga, T., Hibi, M., Hirata, Y., Yamasaki, K., Matsuda, T., Hirano, T. and Kishimoto, T. (1989) Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130. Cell 58, 573.
33. Van Dam, M., Müllberg, J., Schooltink, H., Stoyan, T., Brakenhoff, J.P.J., Graeve, L., Heinrich, P.C. and Rose-John, S. (1993) Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. J. Biol. Chem. 268, 15285.
34. Yamasaki, K., Taga, T., Hirata, Y., Yawata, H., Kawanishi, Y., Seed, B., Taniguchi, T., Hirano, T. and Kishimoto, T. (1988) Cloning and expression of the human interleukin-6 (BSF-2/IFNβ 2) receptor. Science 241, 825.