Monoclonal antibody 2F4/11 recognizes the α chain of a porcine β2 integrin involved in adhesion and complement mediated phagocytosis

Journal of Immunological Methods

Volumn 195, Issue 1-2, 1996, Pages 125-134

  Bullido, R ^a   Alonso, F ^a   Gomez Del Moral M ^a   Ezquerra, A ^a   Alvarez, B ^a   Ortuno E ^a   Dominguez J ^a  

^a INIA   (Spain)

Author keywords

CD11b; Granulocyte; Integrin; Mac 1; Macrophage; Monoclonal antibody; Monocyte; Pig

Indexed keywords

CD11B ANTIGEN; COMPLEMENT; INTEGRIN; MONOCLONAL ANTIBODY;

ANIMAL CELL; ARTICLE; CELL ADHESION; FLOW CYTOMETRY; GRANULOCYTE; IMMUNOBLOTTING; MACROPHAGE; MONOCYTE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; SWINE;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 0030576972     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-1759(96)00095-6     Document Type: Article

References (42)

1. Altieri, D.C., Morrissey, J.H. and Edgington, T.S. (1988) Adhesive receptor Mac-1 coordinates the activation of factor X on stimulated cells of monocytic and myeloid differentiation: an alternative initiation of the coagulation protease cascade. Proc. Natl. Acad. Sci. USA 85, 7462.
2. Anderson, D.C., Miller, L.J., Schmalsteig, F.C., Rothlein, R. and Springer, T.A. (1986) Contributions of the Mac-1 glycoprotein family to adherence-dependent granulocyte functions: structure-function assessments employing subunit-specific monoclonal antibodies. J. Immunol. 137, 15.
3. Arnaout, M., Todd, R., Dana, N., Melamed, J., Schlossman, S. and Colten, H. (1983) Inhibition of phagocytosis of complement C3 or immunoglobulin G-coated particles and of C3bi binding by monoclonal antibodies to a monocyte-granulocyte membrane glycoprotein (mol). J. Clin. Invest. 72, 171.
4. Arnaout, M.A., Lanier, L. and Faller, D.V. (1988) Relative contribution of the leukocyte molecules Mol, LFA-1, p150, 95 (LeuM5) in adhesion of granulocytes and monocytes to vascular endothelium is tissue- and stimulus-specific. J. Cell. Physiol. 137, 305.
5. Beller, D., Springer, T. and Schreiber, R. (1982) Anti-Mac-1 selectively inhibits the mouse and the human type three complement receptor. J. Exp. Med. 156, 1000.
6. Carlos, T.M. and Harlan, J.M. (1990) Membrane proteins involved in phagocyte adherence to endothelium. Immunol. Rev. 114, 5.
7. Carrascosa, A.L., Santarén, J. and Viñuela, E. (1982) Production and titration of African swine fever virus in porcine alveolar macrophages. J. Virol. Methods 3, 303.
8. Damoiseaux, J. (1991) Macrophage heterogeneity in the rat. Ph.D. Thesis, Free University, Amsterdam.
9. Dana, N., Stryrt, B., Griffin, J.D., Todd, R.F., Klempner, M.S. and Arnaout, M.A. (1986) Two functional domains in the phagocyte membrane glycoprotein Mol identified with monoclonal antibodies. J. Immunol. 137, 3259.
10. 2, is expressed by specific macrophage subpopulations in tissue and minor CD8 + lymphocyte subpopulation in peripheral blood. J. Immunol. 155, 35.
11. Diamond, M.S. and Springer, T.A. (1993) A subpopulation of Mac-1 (CD11b/CD18) molecules mediates neutrophil adhesion to ICAM-1 and fibrinogen. J. Cell Biol. 120, 545.
12. El Rouby, S., Praz, F., Halbwachs-Mercarelli, L. and Papiernik, M. (1985) Thymic reticulum in mice. IV. The rosette formation between phagocytic cells of the thymic reticulum and cortical type thymocytes is mediated by complement receptor type three. J. Immunol. 134, 3625.
13. Flotte, T.J., Springer, T.A. and Thorbecke, G.J. (1983) Dendritic cell and macrophage staining by monoclonal antibodies in tissue sections and epidermal sheets. Am. J. Pathol. 111, 112.
14. Freyer, D., Morganroth, M., Rogers, C., Arnaout, M. and Todd, R. (1988) Modulation of surface CD11/CD18 glycoproteins (Mol, LFA-1, p150,95) by human mononuclear phagocytes. Cell Immunol. Immunopathol. 46, 272.
15. Gonzalez, S., Mendoza, C., Sánchez-Vizcaíno, J.M. and Alonso, F. (1990) Inhibitory effect of African swine fever virus on lectin-dependent swine lymphocyte proliferation. Vet. Immunol. Immunopathol. 26, 71.
16. Gordon, S., Keshav, S. and Chung, L.P. (1988) Mononuclear phagocytes: tissue distribution and functional heterogeneity. Curr. Opin. Immunol. 1, 26.
17. Gordon, S., Lawson, L., Rabinowitz, S., Crocker, P.R., Morris, L. and Perry, V.H. (1992) Antigen markers of macrophage differentiation in murine tissues. Curr. Top. Microbiol. Immunol. 181, 1.
18. Graham, I.L. and Brown, E.J. (1991) Extracellular calcium results in a conformational change in Mac-1 (CD11b/CD18) on neutrophils. Differentiation of adhesion and phagocytosis functions of Mac-1. J. Immunol. 146, 685.
19. Gupta, V.B., McConnell, I. and Hopkins, J. (1993) Reactivity of the CD11/CD18 workshop monoclonal antibodies in the sheep. Vet. Immunol. Immunopathol. 39, 93.
20. Halloran, P., Sweeney, S., Strohmeier, C. and Kim, Y.B. (1994) Molecular cloning and identification of the porcine cytolytic trigger molecule G7 as a FcγRIIIα (CD16) homologue. J. Immunol. 153, 2631.
21. Haverson, K., Bailey, M., Higgins, V., Bland, P. and Stokes, C. (1994) Characterization of monoclonal antibodies specific for monocytes, macrophages and granulocytes from porcine peripheral blood and mucosal tissues. J. Immunol. Methods 170, 233.
22. Hildreth, J.E., Holt, V., August, J.T. and Pescovitz, M.D. (1989) Monoclonal antibodies against porcine LFA-1: species cross-reactivity and functional effects of β subunit-specific antibodies. Mol. Immunol. 26, 883.
23. Jacobsen, C., Aasted, B., Broe, M. and Petersen, J. (1993) Reactivities of 20 anti-human monoclonal antibodies with leukocytes from ten different animal species. Vet. Immunol. Immunopathol. 39, 461.
24. Knowles, D.M., Tolidjian, B., Marboe, C., D'Agati, V., Grimes, M. and Chess, L. (1984) Monoclonal anti-human monocyte antibodies OKM1 and OKM5 possess distinctive tissue distributions including differential reactivity with vascular endothelium. J. Immunol. 132, 2170.
25. Kohler, G. and Milstein, C. (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256, 495.
26. Kyewski, B.A., Rouse, R.B. and Kaplan, H.S. (1982) Thymocyte rosettes: multicellular complexes of lymphocytes and bone marrow-derived stromal cells in the mouse thymus. Proc. Natl. Acad. Sci. USA 79, 5646.
27. Larson, R.S. and Springer, T.A. (1990) Structure and function of leukocyte integrins. Immunol. Rev. 114, 181.
28. Lo, S., Van Seventer, G., Levin, S. and Wright, S. (1989) Two leukocyte receptors (CD11a/CD18 and CD11b/CD18) mediate transient adhesion to endothelium by binding to different ligands. J. Immunol. 143, 3325.
29. Lunney, J.K. (1993) Characterization of swine leukocyte differentiation antigens. Immunol. Today 14, 147.
30. Miller, J.M., Schwarting, R. and Springer, T.A. (1986) Regulated expression of the Mac-1, LFA-1, p150,95 glycoprotein family during leukocyte differentiation. J. Immunol. 137, 2891.
31. Mínguez, I., Rueda, A., Domínguez. J. and Sánchez-Vizcaíno, J.M. (1988) Double labeling immunohistological study of African swine fever virus-infected spleen and lymph nodes. Vet. Pathol. 25, 193.
32. Myones, B.L., Dalzell, J.G., Hogg, N. and Ross, G.D. (1988) Neutrophil and monocyte cell surface p150,95 has iC3b-receptor (CR4) activity resembling CR3. J. Clin. Invest. 82, 640.
33. Patarroyo, M., Beatty, P.G., Serhan, C. and Gahmberg, C. (1985) Identification of a cell-surface glycoprotein mediating adhesion in human granulocytes. Scand. J. Immunol. 22, 619.
34. Patarroyo, M., Prieto, J., Rincon, J., Timonen, T., Lundberg, C., Lindbom, L., Asjo, B. and Gahmberg, C. (1990) Leukocyte-cell adhesion: a molecular process fundamental in leukocyte physiology, Immunol. Rev. 114, 67.
35. Robinson, A., White, T. and Mason, D. (1986) Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. Immunology 57, 239.
36. Rosen, H. and Gordon, S. (1987) Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo. J. Exp. Med. 166, 1685.
37. Sänchez-Madrid, F., Nagy, J., Robbins, E., Simon, P. and Springer, T.A. (1983) A human leukocyte differentiation antigen family with distinct alpha subunits and a common beta subunit: the lymphocyte function-associated antigen (LFA-1), the C3bi complement receptor (OKM1/Mac-1), and the 150,95 molecule. J. Exp. Med. 158, 1785.
38. Splitter, G. and Morrison, W.I. (1991) Antigens expressed predominantly on monocytes and granulocytes: identification of bovine CD11b and CD11c. Vet. Immunol. Immunopathol. 27, 87.
39. Vedder, N. and Harlan, J. (1988) Increased surface expression of CD11b/CD18 (Mac-1) is not required for stimulated neutrophil adherence to cultured endothelium. J. Clin. Invest. 81, 676.
40. Wright, S., Rao, P., Van Voorhis, W., Craigmyle, L., Iida, K., Talle, M., Westberg, E., Goldstein, G. and Silverstein, S. (1983) Identification of the C3bi receptor of human monocytes and macrophages with monoclonal antibodies. Proc. Natl. Acad. Sci. USA 80, 5699.
41. Wright, S., Weitz, J., Huang, A., Levin, S., Silverstein, S. and Loike, J. (1988) Complement receptor type three (CD11b/CD18) of human polymorphonuclear leukocytes recognizes fibrinogen. Proc. Natl. Acad. Sci. USA 85, 7734.
42. Ziegler-Heitbrock, H.W.L., Appl, B., Käfferlein, E., Löffler, T., Jahn-Henninger, H., Gutensohn, W., Noress, J.R., McCullough, K., Passlick, B., Labeta, M.O. and Izbicki, J. (1994) The antibody MY4 recognizes CD14 on porcine monocytes and macrophages. Scand. J. Immunol. 40, 509.