GABAergic neuronal activity and mRNA levels for both forms of glutamic acid decarboxylase (GAD65 and GAD67) are reduced in the diagonal band of Broca during the afternoon of proestrus

Brain Research

Volumn 733, Issue 1, 1996, Pages 46-55

  Grattan, David R ^a,b   Rocca, Meredith S ^a   Strauss, Kenneth I ^c   Sagrillo, Cathy A ^a   Selmanoff, Michael ^a   McCarthy, Margaret M ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Aminobutyric acid turnover; Gonadal steroid; Gonadotropin releasing hormone; Hypothalamus; Medial preoptic nucleus; Rat

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; GONADORELIN; LUTEINIZING HORMONE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; ESTRUS CYCLE; FEMALE; NONHUMAN; PREOPTIC AREA; PRIORITY JOURNAL; PROESTRUS; RADIOIMMUNOASSAY; RAT;

EID: 0030576902     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00532-X     Document Type: Article

References (55)

1. B receptor-mediated inhibition of the preovulatory luteinizing hormone surge in female rats, Brain Res., 562 (1991) 169-172.
2. B receptor agonist, in ovariectomized rats, Neuroendocrinology, 56 (1992) 141-147.
3. B receptor antagonists on NMDA-induced and noradrenaline-induced luteinizing-hormone release in the ovariectomized estrogen-primed rat, Neuroendocrinology, 57 (1993) 28-33.
4. [4] Bergen, H.T., Hejtmancik, J.F. and Pfaff, D.W., Effects of gamma-aminobutyric acid receptor agonists and antagonist on LHRH-synthesizing neurons as detected by immunocytochemistry and in situ hybridization, Exp. Brain Res., 87 (1991) 46-56.
5. [5] Bradford, M.M., A rapid and sensitive method for the quantitation of microgram quantities of protein using the principle of protein-dye binding. Anal. Biochem., 72 (1976) 248-254.
6. [6] Buijs, R.M., Hou, Y.-X., Shinn, S. and Renaud, L.P., Ultrastructural evidence for intra and extranuclear projections of GABAergic neurons of the suprachiasmatic nucleus. J. Comp. Neurol., 340 (1994) 381-391.
7. [7] Casanueva, F., Apud, J.A., Masotto, C., Cocchi, D., Locatelli, V., Racagni, G. and Muller, E.E., Daily fluctuations in the activity of the tuberoinfundibular GABAergic system and prolactin levels, Neuroendocrinology, 39 (1984) 367-370.
8. [8] Cattabeni, F., Maggi, A., Monduzzi, M., De Angelis, L. and Racagni, N., GABA: Circadian fluctuations in rat hypothalamus, J. Neurochem., 31 (1978) 565-567.
9. [9] Demling, J., Fuchs, E., Baumert, M. and Wuttke, W., Preoptic catecholamine, GABA, and glutamate release in ovariectomized and ovariectomized estrogen-primed rats utilizing a push-pull cannula technique, Neuroendocrinology, 41 (1985) 212-218.
10. [10] Edwards, A.L. 1954 Statistical Methods for the Behavioural Sciences, Rinehart, New York, 1954, pp. 300-314.
11. [11] Erlander, M.G. and Tobin, A.J., The structural and functional heterogeneity of glutamic acid decarboxylase: A review, Neurochem. Res., 16 (1991) 215-226.
12. [12] Flügge, G., Oertel, W.H. and Wuttke, W., Evidence for estrogen receptive GABAergic neurons in the preoptic/anterior hypothalamic area of the rat brain, Neuroendocrinology, 43 (1986) 1-5.
13. [13] Fuchs, E., Mansky, T., Stock, K.-W., Vijayan, E. and Wuttke, W., Involvement of catecholamines and glutamate in GABAergic mechanism regulatory to luteinizing hormone and prolactin secretion, Neuroendocrinology, 38 (1984) 484-489.
14. [14] Grattan, D.R. and Selmanoff, M., Regional variation in γ-aminobutyric acid turnover: Effect of castration on γ-aminobutyric acid turnover in microdissected brain regions of the male rat, J. Neurochem., 60 (1993) 2254-2264.
15. [15] Grattan, D.R. and Selmanoff, M., Castration-induced decrease in the activity of medial preoptic and tuberoinfundibular GABAergic neurons is prevented by testosterone, Neuroendocrinology, 60 (1994) 141-149.
16. [16] Grattan, D.R. and Selmanoff, M., Prolactin- and testosterone-induced inhibition of luteinizing hormone secretion after orchidectomy: Role of preoptic and tuberoinfundibular γ-aminobutyric acidergic neurons, J. Endocrinol., 143 (1994) 165-174.
17. [17] Hartman, R.D., He, J.-R. and Barraclough, C.A., γ-Aminobutyric acid-A and -B receptor antagonists increase luteinizing hormone-releasing hormone neuronal responsiveness to intracerebroventricular norepinephrine in ovariectomized estrogen-treated rats. Endocrinology, 127 (1990) 1336-1345.
18. [18] Herbison, A.E. and Dyer, R.G., Effect on luteinizing hormone secretion of GABA receptor modulation in the medial preoptic area at the time of proestrous luteinizing hormone surge, Neuroendocrinology, 53 (1991) 317-320.
19. [19] Herbison, A.E. and Theodosis, D.T., Localization of oestrogen receptors in preoptic neurons containing neurotensin but not tyrosine hydroxylase, cholecystokinin or luteinizing hormone-releasing hormone in the male and female rat, Neuroscience, 50 (1992) 283-298.
20. [20] Herbison, A.E., Heavens, R.P., Dye, S. and Dyer, R.G., Acute action of oestrogen on medial preoptic gamma-aminobutyric acid neurons: Correlation with estrogen negative feedback on luteinizing hormone secretion, J. Neuroendocrinol., 3 (1991) 101-106.
21. [21] Herbison, A.E., Augood, S.J. and McGowen, E.M., Expression of glutamic acid decarboxylase messenger RNA in rat medial preoptic area neurones during the oestrus cycle and after ovariectomy, Mol. Brain Res., 14 (1992) 310-316.
22. [22] Hiatt, E.S., Brunetta, P.G., Seiler, G.R., Barney, S.A., Selles, W.D., Wooledge, K.H. and King, J.C., Subgroups of luteinizing hormone-releasing hormone perikarya defined by computer analyses in the basal forebrain of intact female rats, Endocrinology, 130 (1992) 1030-1043.
23. [23] Hiruma, H., Sano, A. and Kimura, F., Injection of bicuculline elicits firing of luteinizing hormone-releasing hormone pulse generator in muscimol-treated ovariectomized rats, Brain Res., 641 (1994) 191-197.
24. [24] Huang, X. and Harlan, R.E., Absence of androgen receptors in LHRH immunoreactive neurons, Brain Res., 624 (1993) 309-311.
25. [25] Jarry, H., Perschl, A. and Wuttke, W., Further evidence that preoptic anterior hypothalamic GABAergic neurons are part of the GnRH pulse and surge generator, Acta Endocrinol. (Copenh.), 118 (1988) 573-579.
26. [26] Jarry, H., Leonhardt, S. and Wuttke, W., Gamma-aminobutyric acid neurons in the preoptic/anterior hypothalamic area synchronize the phasic activity of the gonadotropin-releasing hormone pulse gererator in ovariectomized rats. Neuroendocrinology, 53 (1991) 261-267.
27. [27] Jarry, H., Hirsch, B., Leonhardt, S. and Wuttke, W., Amino acid neurotransmitter release in the preoptic area of rats during the positive feedback action of estradiol on LH release, Neuroendocrinology, 56 (1992) 133-140.
28. [28] Kimura, F. and Jinnai, K., Bicuculline infusions advance the timing of luteinizing hormone surge in proestrous rats: Comparisons with naloxone effects, Horm. Behav., 28 (1996) 424-430.
29. [29] Lee, S. and Pelletier, G., Chronic administration of muscimol and pentobarbital decreases gonadotropin-releasing hormone mRNA levels in the male rat hypothalamus determined by quantitative in situ hybridization, Neuroendocrinology, 58 (1993) 136-139.
30. [30] Lee, W.-S., Smith, M.S. and Hoffman, G.E., Luteinizing hormone-releasing hormone neurons express Fos protein during the proestrous surge of luteinizing hormone, Proc. Natl. Acad. Sci. USA, 87 (1990) 5163-5167.
31. [31] Lee, W.-S., Smith, M.S. and Hoffman, G.E., cFos activity identifies recruitment of luteinizing hormone-releasing hormone neurons during the ascending phase of the proestrous luteinizing hormone surge, J. Neuroendocrinol., 4 (1992) 161-166.
32. [32] Lee, W.S., Abbud, R., Smith, M.S. and Hoffman, G.E., LHRH neurons express cJun protein during the proestrous surge of luteinizing hormone, Endocrinology, 130 (1992) 3101-3103.
33. [33] Leigh, A.J., Carter, N.D., Horten, R., Silverlight, J.J. and Wilson, C.A., Ovarian steroid regulation of glutamic acid decarboxylase gene expression in individual hypothalamic nuclei, J. Neuroendocrinol., 2 (1990) 433-438.
34. [34] Léránth, C., MacLusky, N.J., Sakamoto, H., Shanabrough, M. and Naftolin, F., Glutamic acid decarboxylase-containing axons synapse on LHRH neurons in the rat medial preoptic area, Neuroendocrinology, 40 (1985) 536-539.
35. [35] Léránth, C., MacLusky, N.J., Shanabrough, M. and Naftolin, F., Catecholaminergic innervation of luteinizing hormone-releasing hormone and glutamic acid decarboxylase immunopositive neurons in the rat medial preoptic area, Neuroendocrinology, 48 (1988) 591-602.
36. [36] Mansky, T., Mestres-Ventura, P. and Wuttke, W., Involvement of GABA in the feedback action of estradiol on gonadotropin and prolactin release: Hypothalamic GABA and catecholamine turnover rates, Brain Res., 231 (1982) 353-364.
37. [37] Martin, D.L. and Rimvall, K., Regulation of γ-aminobutyric acid synthesis in the brain, J. Neurochem., 60 (1993) 395-407.
38. [38] McCarthy, M.M., Kaufman, L.C., Brooks, P.J. and Pfaff, D.W., Estrogen modulation of mRNA for two forms of glutamic acid decarboxylase (GAD) in female rat brain, J. Comp. Neurol., 360 (1995) 685-697.
39. [39] Moore, R.Y. and Speh, J.C., GABA is the principal neurotransmitter of the circadian system, Neurosci. Lett., 150 (1993) 112-116.
40. [40] Morello, H., Caligaris, L., Haymal, B. and Taleisnik, S., Daily variations in the sensitivity of proestrous LH surge in the inhibitory effect of intraventricular injection of 5-HT or GABA in rats, Can. J. Physiol. Pharmacol., 70 (1992) 447-451.
41. [41] Mugnaini, E. and Oertel, W.H., An atlas of the distribution of GABAergic neurons and terminals in the rat CNS as revealed by GAD immunocytochemistry. In A. Björklund and T. Hökfelt (Eds.), Handbook of Chemical Neuroanatomy, Vol. 4: GABA and Neuropeptides in the CNS, Part 1, Elsevier, Amsterdam, 1985, pp. 436-608.
42. [42] Palkovits, M. and Brownstein, M.J., Maps and Guide to Microdissection of the Rat Brain, Elsevier, New York, 1988.
43. [43] Park, S.-K. and Selmanoff, M., Dose-dependent suppression of postcastration luteinizing hormone secretion exerted by exogenous prolactin administration in male rats: A model for studying hyperprolactinemic hypogonadism, Neuroendocrinology, 53 (1991) 404-410.
44. A receptor subunit mRNAs in cells of the preoptic area: Colocalization with LHRH mRNA using dual label in situ hybridization histochemistry, Endocr. J., 1 (1993) 29-34.
45. [45] Pfaff, D.W. and Keiner, M., Atlas of estradiol-concentrating cells in the central nervous system of the female rat, J. Comp. Neurol., 151 (1973) 121-158.
46. [46] Porkka-Heiskanen, T., Urban, J.H., Turek, F.W. and Levine, J.E., Gene expression in a sub-population of luteinizing hormone-releasing hormone (LHRH) neurons prior to the preovulatory gonadotropin surge, J. Neurosci., 14 (1994) 5548-5558.
47. [47] Sagrillo, C.A. and Selmanoff, M., Castration decreases single cell levels of mRNA encoding glutamic acid decarboxylase in the diagonal band of Broca and the sexually dimorphic nucleus of the preoptic area, J. Neuroendocrinol., (1996) in press.
48. [48] Seltzer, A.M. and Donoso, A.O., Restraining action of GABA on estradiol-induced LH surge in the rat: GABA activity in brain nuclei and effects of GABA mimetics in the medial preoptic nucleus, Neuroendocrinology, 55 (1992) 28-34.
49. [49] Shivers, B.D., Harlan, R.E., Morrell, J.I. and Pfaff, D.W., Absence of estradiol concentration in cell nuclei of LHRH-immunoreactive neurons. Nature, 304 (1983) 345-347.
50. [50] Stoflet, E.S., Koeberl, D.D., Sarkar, G. and Sommer, S.S. Genomic amplification with transcript sequencing, Science, 239 (1988) 491-494.
51. [51] Strauss, K.I. and Jakobowitz, D.M., Quantitative measurement of calretinin and β-actin mRNA in rat brain micropunches without prior isolation of RNA, Mol. Brain Res., 20 (1993) 229-239.
52. [52] Van der Beek, E.M., Van Oudheusden, H.J., Buijs, R.M., Van der Donk, H.A., Van der Hurk, R. and Wiegant, V.M., Preferential induction of c-fos immunoreactivity in vasoactive intestinal polypeptide-innervated gonadotropin-releasing hormone neurons during a steroid-induced luteinizing hormone surge in the female rat, Endocrinology, 134 (1994) 2636-2644.
53. [53] Van der Hayden, J.A.M. and Korf, J., Regional levels of GABA in the brain: Rapid semiautomated assay and prevention of post mortem increase by 3-mercaptopropionic acid, J. Neurochem., 31 (1978) 197-203.
54. [54] Weiland, N.G., Glutamic acid decarboxylase messenger ribonucleic acid is regulated by estradiol and progesterone in the hippocampus, Endocrinology, 131 (1993) 2697-2702.
55. [55] Winer, B.J., Statistical Principles in Experimental Design, McGraw-Hill, New York, 2nd Edn., 1971.