-
1
-
-
0025900338
-
Nucleoside salvage and resistance to antimetabolite anticancer agents
-
1. Fox M, Boyle JM and Kinsella AR, Nucleoside salvage and resistance to antimetabolite anticancer agents. Br J Cancer 64: 428-436, 1991.
-
(1991)
Br J Cancer
, vol.64
, pp. 428-436
-
-
Fox, M.1
Boyle, J.M.2
Kinsella, A.R.3
-
2
-
-
0025254476
-
DNA amplification is rare in normal human cells
-
2. Wright JA, Smith SH, Watt FM, Hancock MC, Hudson DL and Stark GR, DNA amplification is rare in normal human cells. Proc Natl Acad Sci 87: 1791-1795, 1990.
-
(1990)
Proc Natl Acad Sci
, vol.87
, pp. 1791-1795
-
-
Wright, J.A.1
Smith, S.H.2
Watt, F.M.3
Hancock, M.C.4
Hudson, D.L.5
Stark, G.R.6
-
3
-
-
0020955571
-
Biochemical strategy of cancer cells and the design of chemotherapy. G.H.A. Clowes Memorial Lecture
-
3. Weber G, Biochemical strategy of cancer cells and the design of chemotherapy. G.H.A. Clowes Memorial Lecture. Cancer Res 43: 3466-3492, 1983.
-
(1983)
Cancer Res
, vol.43
, pp. 3466-3492
-
-
Weber, G.1
-
4
-
-
0017721494
-
Amplification of dihydrofolate reductase genes in methotrexate-resistant cultured mouse cells
-
Cold Spring Harbor Symp.
-
4. Schimke RT, Alt FW, Kellems RE, Kaufman RJ and Bertino JR, Amplification of dihydrofolate reductase genes in methotrexate-resistant cultured mouse cells. Cold Spring Harbor Symp. Quant Biol 42: 649-654, 1977.
-
(1977)
Quant Biol
, vol.42
, pp. 649-654
-
-
Schimke, R.T.1
Alt, F.W.2
Kellems, R.E.3
Kaufman, R.J.4
Bertino, J.R.5
-
5
-
-
0018787266
-
Gene amplification causes over production of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells
-
5. Wahl GM, Paggett RA and Stark GR, Gene amplification causes over production of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells. J Biol Chem 254: 8679-8685, 1979.
-
(1979)
J Biol Chem
, vol.254
, pp. 8679-8685
-
-
Wahl, G.M.1
Paggett, R.A.2
Stark, G.R.3
-
6
-
-
0025908157
-
Decreasing sensitivity to cytotoxic agents parallels increasing tumourigenicity in human fibroblasts
-
6. Kinsella AR and Haran MS, Decreasing sensitivity to cytotoxic agents parallels increasing tumourigenicity in human fibroblasts. Cancer Res 51: 1855-1859, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 1855-1859
-
-
Kinsella, A.R.1
Haran, M.S.2
-
7
-
-
0016588444
-
Membrane transport of purine and pyrimidine bases and nucleosides in animal cells
-
7. Berlin RD and Oliver JM, Membrane transport of purine and pyrimidine bases and nucleosides in animal cells. Int Rev Cytol 42: 287-336, 1972.
-
(1972)
Int Rev Cytol
, vol.42
, pp. 287-336
-
-
Berlin, R.D.1
Oliver, J.M.2
-
8
-
-
77957077456
-
Permeation of nucleosides, nucleic acid bases and nucleotides in animals cells
-
8. Plagemann PG and Wohlhueter RM, Permeation of nucleosides, nucleic acid bases and nucleotides in animals cells. Curr Topics Membrane Transp 14: 225-330, 1980.
-
(1980)
Curr Topics Membrane Transp
, vol.14
, pp. 225-330
-
-
Plagemann, P.G.1
Wohlhueter, R.M.2
-
9
-
-
0020502155
-
Nucleoside transport in animal cells
-
9. Young JP and Jarvis SM, Nucleoside transport in animal cells. Rev Biosci Res 3: 309-322, 1983.
-
(1983)
Rev Biosci Res
, vol.3
, pp. 309-322
-
-
Young, J.P.1
Jarvis, S.M.2
-
10
-
-
0014753962
-
Influence of dipyridamole (Persantin) on myocardial adenosine metabolism
-
10. Kubler W, Spieckermann PG and Bretschneider HJ, Influence of dipyridamole (Persantin) on myocardial adenosine metabolism. J Mol Cell Cardiol 1: 23-38, 1970.
-
(1970)
J Mol Cell Cardiol
, vol.1
, pp. 23-38
-
-
Kubler, W.1
Spieckermann, P.G.2
Bretschneider, H.J.3
-
11
-
-
0022549958
-
Inhibition of nucleoside and nucleobase transport and nitrobenzylthioinosine binding by dilazep and hexobendine
-
11. Plagemann PG and Kraup M, Inhibition of nucleoside and nucleobase transport and nitrobenzylthioinosine binding by dilazep and hexobendine. Biochem Pharmacol 35: 2559-2567, 1988.
-
(1988)
Biochem Pharmacol
, vol.35
, pp. 2559-2567
-
-
Plagemann, P.G.1
Kraup, M.2
-
12
-
-
0015070967
-
Nucleoside transport by Novikoff rat hepatoma cells growing in suspension culture. Specificity and mechanism of transport reactions and relationship to nucleoside incorporation into nucleic acids
-
12. Plagemann PGW, Nucleoside transport by Novikoff rat hepatoma cells growing in suspension culture. Specificity and mechanism of transport reactions and relationship to nucleoside incorporation into nucleic acids. Biochem Biophys Acta 233: 688-701, 1971.
-
(1971)
Biochem Biophys Acta
, vol.233
, pp. 688-701
-
-
Plagemann, P.G.W.1
-
13
-
-
0020583567
-
Effects of Acivicin and dipyridamole on hepatoma 3924A cells
-
13. Zhen Y-S, Lui MS and Weber G, Effects of Acivicin and dipyridamole on hepatoma 3924A cells. Cancer Res 43: 1616-1619, 1983.
-
(1983)
Cancer Res
, vol.43
, pp. 1616-1619
-
-
Zhen, Y.-S.1
Lui, M.S.2
Weber, G.3
-
14
-
-
0014428576
-
Studies on the uptake of nucleic acid precursors into cells in tissue culture
-
14. Scholtissek C, Studies on the uptake of nucleic acid precursors into cells in tissue culture. Biochem Biophys Acta 158: 435-447, 1968.
-
(1968)
Biochem Biophys Acta
, vol.158
, pp. 435-447
-
-
Scholtissek, C.1
-
15
-
-
0021806785
-
Augmentation of 5-fluorouracil cytotoxicity in human cancer cells by dipyridamole
-
15. Grem JL and Fischer PH, Augmentation of 5-fluorouracil cytotoxicity in human cancer cells by dipyridamole. Cancer Res 45: 2967-2972, 1985.
-
(1985)
Cancer Res
, vol.45
, pp. 2967-2972
-
-
Grem, J.L.1
Fischer, P.H.2
-
16
-
-
0015521096
-
Effects of persantin on several transport systems of murine leukemia cells
-
16. Kessel D and Dodd DC, Effects of persantin on several transport systems of murine leukemia cells. Biochem Biophys Acta 288: 190-194, 1972.
-
(1972)
Biochem Biophys Acta
, vol.288
, pp. 190-194
-
-
Kessel, D.1
Dodd, D.C.2
-
17
-
-
0025880971
-
Drug-target interactions: Only the first step in the commitment to a programmed cell death?
-
17. Dive C and Hickman JA, Drug-target interactions: only the first step in the commitment to a programmed cell death? Br J Cancer 64: 192-196, 1991.
-
(1991)
Br J Cancer
, vol.64
, pp. 192-196
-
-
Dive, C.1
Hickman, J.A.2
-
18
-
-
0028204160
-
DNA strand breaks: The DNA template alterations that trigger p53-dependent-DNA damage response pathways
-
18. Nelson WG and Kastan MB, DNA strand breaks: the DNA template alterations that trigger p53-dependent-DNA damage response pathways. Mol Cell Biol 14: 1815-1823, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 1815-1823
-
-
Nelson, W.G.1
Kastan, M.B.2
-
19
-
-
0023811519
-
Multistep carcinogenesis of normal human fibroblasts
-
19. Namba M, Nishitani K, Fukushima F and Kimoto T, Multistep carcinogenesis of normal human fibroblasts. Anticancer Res 8: 947-958, 1988.
-
(1988)
Anticancer Res
, vol.8
, pp. 947-958
-
-
Namba, M.1
Nishitani, K.2
Fukushima, F.3
Kimoto, T.4
-
20
-
-
0025066416
-
Introduction of the activated N-ras oncogene into human fibroblasts by retroviral vector induces morphological transformation and tumourigenicity
-
20. Kinsella AR, Fiszer-Maliszewska L, Mitchell ELD, Guo YP, Fox M and Scott D, Introduction of the activated N-ras oncogene into human fibroblasts by retroviral vector induces morphological transformation and tumourigenicity. Carcinogenesis 11: 1803-1809, 1990.
-
(1990)
Carcinogenesis
, vol.11
, pp. 1803-1809
-
-
Kinsella, A.R.1
Fiszer-Maliszewska, L.2
Mitchell, E.L.D.3
Guo, Y.P.4
Fox, M.5
Scott, D.6
-
21
-
-
0029589690
-
Differences in resistance to 5-FU as a function of cell cycle delay and not apoptosis
-
21. Pickard M, Dive C and Kinsella AR, Differences in resistance to 5-FU as a function of cell cycle delay and not apoptosis. Br J Cancer 72: 1389-1396, 1995.
-
(1995)
Br J Cancer
, vol.72
, pp. 1389-1396
-
-
Pickard, M.1
Dive, C.2
Kinsella, A.R.3
-
22
-
-
0027500246
-
Induction of nuclear accumulation of the tumour suppressor protein p53 by DNA-damaging agents
-
22. Fritsche M, Haessler C and Brander G, Induction of nuclear accumulation of the tumour suppressor protein p53 by DNA-damaging agents. Oncogene 8: 307-318, 1993.
-
(1993)
Oncogene
, vol.8
, pp. 307-318
-
-
Fritsche, M.1
Haessler, C.2
Brander, G.3
-
23
-
-
0004053611
-
-
John Wiley and Sons, New York, Chichester, Brisbane, Toronto, Singapore
-
23. Voet D and Voet JG, Biochemistry, pp. 815-816. John Wiley and Sons, New York, Chichester, Brisbane, Toronto, Singapore, 1995.
-
(1995)
Biochemistry
, pp. 815-816
-
-
Voet, D.1
Voet, J.G.2
-
24
-
-
0016366669
-
Purification and amino acid analysis of an active site peptide from thymidylate synthetase containing covalently bound 5′-fluoro-2′-deoxyuridylate and methylene tetrachloride
-
24. Sommer A and Santi DV, Purification and amino acid analysis of an active site peptide from thymidylate synthetase containing covalently bound 5′-fluoro-2′-deoxyuridylate and methylene tetrachloride. Biochem Biophys Res Commun 57: 689-696, 1974.
-
(1974)
Biochem Biophys Res Commun
, vol.57
, pp. 689-696
-
-
Sommer, A.1
Santi, D.V.2
-
25
-
-
0025611018
-
Metabolism and mechanism of action of 5-fluorouracil
-
25. Parker WB and Cheng YC, Metabolism and mechanism of action of 5-fluorouracil. Pharmac Ther 48: 381-395, 1990.
-
(1990)
Pharmac Ther
, vol.48
, pp. 381-395
-
-
Parker, W.B.1
Cheng, Y.C.2
-
26
-
-
0020694938
-
Effects of 5-fluoro-2′-deoxyuridine on DNA metabolism HeLa cells
-
26. Cheng YC and Nakayama K, Effects of 5-fluoro-2′-deoxyuridine on DNA metabolism HeLa cells. Mol Pharmocol 23: 171-174, 1983.
-
(1983)
Mol Pharmocol
, vol.23
, pp. 171-174
-
-
Cheng, Y.C.1
Nakayama, K.2
-
27
-
-
0023655202
-
Deoxyribonucleoside triphosphate imbalance-fluorodeoxyuridine induced DNA double strand breaks in mouse FM3A cells and the mechanisms of cell death
-
27. Yoshioka A, Tanaka S and Hiraoka O, Deoxyribonucleoside triphosphate imbalance-fluorodeoxyuridine induced DNA double strand breaks in mouse FM3A cells and the mechanisms of cell death. J Biol Chem 262: 8235-8241, 1987.
-
(1987)
J Biol Chem
, vol.262
, pp. 8235-8241
-
-
Yoshioka, A.1
Tanaka, S.2
Hiraoka, O.3
-
28
-
-
0022618268
-
The inhibitory effects of 5-fluorouracil on the metabolism of preribosomal and ribosomal RNA in L-1210 cells in vitro
-
28. Kanamaru R, Kakuta H and Sato T, The inhibitory effects of 5-fluorouracil on the metabolism of preribosomal and ribosomal RNA in L-1210 cells in vitro. Cancer Chemother Pharmacol 17: 43-46, 1986.
-
(1986)
Cancer Chemother Pharmacol
, vol.17
, pp. 43-46
-
-
Kanamaru, R.1
Kakuta, H.2
Sato, T.3
-
29
-
-
0018668384
-
The effect of 5-fluorouracil on the synthesis and translation of poly(A) RNA from regenerating liver
-
29. Carrico CK and Glazer RI, The effect of 5-fluorouracil on the synthesis and translation of poly(A) RNA from regenerating liver. Cancer Res 39: 3694-3701, 1979.
-
(1979)
Cancer Res
, vol.39
, pp. 3694-3701
-
-
Carrico, C.K.1
Glazer, R.I.2
-
30
-
-
0021986402
-
Effects of 5-fluorouracil on dihydrofolate reductase mRNA from methotrexate resistant KB cells
-
30. Dolnick BJ and Pink JJ, Effects of 5-fluorouracil on dihydrofolate reductase mRNA from methotrexate resistant KB cells. J Biol Chem 260: 3006-3014, 1985.
-
(1985)
J Biol Chem
, vol.260
, pp. 3006-3014
-
-
Dolnick, B.J.1
Pink, J.J.2
-
31
-
-
0018926163
-
Assessment of growth limiting events caused by 5-fluorouracil in mouse cells and in human cells
-
31. Evans RM, Laskin JD and Hakala MT, Assessment of growth limiting events caused by 5-fluorouracil in mouse cells and in human cells. Cancer Res 40: 4113-4122, 1980.
-
(1980)
Cancer Res
, vol.40
, pp. 4113-4122
-
-
Evans, R.M.1
Laskin, J.D.2
Hakala, M.T.3
-
32
-
-
0014337436
-
On the mechanism of the lethal action of 5-fluorouracil on mouse L cells
-
32. Macdoc-Jones H and Bruce WR, On the mechanism of the lethal action of 5-fluorouracil on mouse L cells. Cancer Res 28: 1976-1981, 1968.
-
(1968)
Cancer Res
, vol.28
, pp. 1976-1981
-
-
Macdoc-Jones, H.1
Bruce, W.R.2
-
33
-
-
0012074248
-
Folinic acid alters the mechanism by which dipyridamole increases the toxicity of fluorouracil in human colon cancer cells
-
33. Miller EM, Wilson JF and Fischer PH, Folinic acid alters the mechanism by which dipyridamole increases the toxicity of fluorouracil in human colon cancer cells. Proc Am Ass Cancer Res 28: 326-331, 1987.
-
(1987)
Proc Am Ass Cancer Res
, vol.28
, pp. 326-331
-
-
Miller, E.M.1
Wilson, J.F.2
Fischer, P.H.3
-
34
-
-
0012050346
-
Dipyridamole potentiation of FUDR activity against human colon cancer in vitro and in patients
-
34. Schwartz J, Alberts D, Einspahr J, Peng YM and Spears P, Dipyridamole potentiation of FUDR activity against human colon cancer in vitro and in patients. Proc Am Soc Chem Oncol 6: 83-87, 1987.
-
(1987)
Proc Am Soc Chem Oncol
, vol.6
, pp. 83-87
-
-
Schwartz, J.1
Alberts, D.2
Einspahr, J.3
Peng, Y.M.4
Spears, P.5
-
35
-
-
0021733929
-
Comparative levels of tissue enzymes concerned in the early metabolism of 5-fluorouracil in normal and malignant colorectal tissue
-
35. Finnan PJ, Koklitis PA, Chisholm EM and Giles GR, Comparative levels of tissue enzymes concerned in the early metabolism of 5-fluorouracil in normal and malignant colorectal tissue. Br J Cancer 50: 711-715, 1984.
-
(1984)
Br J Cancer
, vol.50
, pp. 711-715
-
-
Finnan, P.J.1
Koklitis, P.A.2
Chisholm, E.M.3
Giles, G.R.4
-
36
-
-
0026318356
-
Participation of p53 in the cellular response to DNA damage
-
36. Kastan MB, Onyekwere O, Sidransky D, Vogelstein B and Craig RW, Participation of p53 in the cellular response to DNA damage. Cancer Res 51: 6304-6311, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 6304-6311
-
-
Kastan, M.B.1
Onyekwere, O.2
Sidransky, D.3
Vogelstein, B.4
Craig, R.W.5
-
37
-
-
0027970713
-
DNA damage triggers a prolonged p53-dependent G1 arrest and long term induction of Cip1 in normal human fibroblasts
-
37. DiLeonardo A, Linke SP, Clarkin K and Wahl GM, DNA damage triggers a prolonged p53-dependent G1 arrest and long term induction of Cip1 in normal human fibroblasts. Genes Development 8: 2540-2551, 1994.
-
(1994)
Genes Development
, vol.8
, pp. 2540-2551
-
-
DiLeonardo, A.1
Linke, S.P.2
Clarkin, K.3
Wahl, G.M.4
-
38
-
-
0026656853
-
Wildtype p53 is a cell cycle checkpoint determinant following irradiation
-
38. Kuerbitz SJ, Plunkett BS, Walsh WV and Kastan MB, Wildtype p53 is a cell cycle checkpoint determinant following irradiation. Proc Natl Acad Sci 89: 7491-7495, 1992.
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 7491-7495
-
-
Kuerbitz, S.J.1
Plunkett, B.S.2
Walsh, W.V.3
Kastan, M.B.4
-
39
-
-
0028261160
-
Escape from senescence in human diploid fibroblasts induced directly by mutant p53
-
39. Bond JA, Wyllie FS and Wynford-Thomas D, Escape from senescence in human diploid fibroblasts induced directly by mutant p53. Oncogene 9: 1885-1889, 1994.
-
(1994)
Oncogene
, vol.9
, pp. 1885-1889
-
-
Bond, J.A.1
Wyllie, F.S.2
Wynford-Thomas, D.3
-
40
-
-
0027451668
-
P53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
40. Lowe SW, Ruley EH, Jacks T and Houseman DE, P53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967, 1993.
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, E.H.2
Jacks, T.3
Houseman, D.E.4
-
41
-
-
0027319521
-
p53 is required for radiation induced apoptosis in mouse thymocytes
-
41. Lowe SW, Schmitt EM, Smith SW, Osborne B and Jacks T, p53 is required for radiation induced apoptosis in mouse thymocytes. Nature 362: 847-849, 1993.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.4
Jacks, T.5
-
42
-
-
0027258466
-
Thymocyte apoptosis induced by p53 dependent and independent pathways
-
42. Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, Hooper ML and Wyllie AH, Thymocyte apoptosis induced by p53 dependent and independent pathways. Nature 362: 849-852, 1993.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wyllie, A.H.7
-
43
-
-
0029024691
-
1
-
1. Cancer Res 55: 2404-2409, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 2404-2409
-
-
Bond, J.A.1
Blaydes, J.P.2
Rowson, J.3
Haughton, M.F.4
Smith, J.R.5
Wynford-Thomas, D.6
Wyllie, F.S.7
|