Homo-N-nucleosides: Incorporation into oligonucleotides and antiviral activity

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 13, 1996, Pages 1465-1468

  Hossain, N ^a   Hendrix, C ^a   Lescrinier, E ^a   Van Aerschot, A ^a   Busson, R ^a   De Clercq, E ^a   Herdewijn, P ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOSIDE DERIVATIVE; OLIGONUCLEOTIDE;

AMINO ACID SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; DRUG CONFORMATION; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS; MOLECULAR RECOGNITION; NONHUMAN; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

HERPES; HUMAN HERPESVIRUS 2;

EID: 0030576310     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(96)00254-5     Document Type: Article

References (16)

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16. 16. Note added in proof : a paper describing the synthesis of analogous homo-N-nucleosides but with the base residing in the α-conformation recently appeared. No results of incorporation studies were reported. Scremin, C.L.; Boal, J.H.; Wilk, A.; Phillips, L.R.; Beaucage, S.L. Bioorg. Med. Chem. Lett. 1996, 6, 207-212.