Immunocytochemical localization of a full-length myotonin protein kinase in rat L6 myoblasts

Neuroscience Letters

Volumn 218, Issue 3, 1996, Pages 214-216

  Saitoh, Naoto ^a   Sasagawa, Noboru ^a   Koike, Hisashi ^a   Shimokawa, Masatake ^a   Sorimachi, Hiroyuki ^a   Ishiura, Shoichi ^a   Suzuki, Koichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Immunofluorescence microscopy; Myogenic cell; Myotonic dystrophy; Myotonin protein kinase; Triplet repeat

Indexed keywords

COMPLEMENTARY DNA; PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; MYOBLAST; MYOTONIC DYSTROPHY; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM;

ANIMALS; CELL LINE; DNA, COMPLEMENTARY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MUSCLE, SKELETAL; MUTAGENESIS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RATS; TRANSFECTION;

EID: 0030575949     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(96)13154-2     Document Type: Article

References (15)

1. [1] Brook, J.D., McCurrach, M.E., Harley, H.G., Buckler, A.J., Church, D., Aburatani, H., Hunter, H., Stanton, V.P., Thirion, J.P., Hudson, T., Sohn, R., Zemelman, B., Snell, R.G., Rundle, S.A., Crow, S., Davies, J., Shelbourne, P., Buxton, J., Jones, C., Juvonen, V., Johnson, K., Harper, P.S., Shaw, D.J. and Housman, D.E., Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member, Cell, 68 (1992) 799-808.
2. [2] Fu, Y.H., Pizzuti, A., Fenwick, R.G. Jr., King, J., Rajnarayan, S., Dunne, P.W., Dubel, J., Nasser, G.A., Ashizawa, T., de Jong, P., Wieringa, B., Korneluk, R.G., Perryman, M.B., Epstein, H.F. and Caskey, C.T., An unstable triplet repeat in a gene related to myotonic muscular dystrophy, Science, 255 (1992) 1256-1258.
3. [3] Harper, P.S., Myotonic Dystrophy, W.W. Saunders, London, 1989.
4. [4] Howeler, C.J., Busch, H.F.M., Geraedts, J.P.M., Niermeijer, M.F. and Staal, A., Anticipation in myotonic dystrophy: fact or fiction?, Brain, 112 (1989) 779-797.
5. [5] Jansen, G., Mahadevan, M., Amemiya, C., Wormskamp, N., Segers, B., Hendriks, W., O'Hoy, K., Baird, S., Sabourin, L., Lennon, G., Jap, P.L., Ikes, D., Coerwinkel, M., Hofker, M., Carrano, A.V., De Jong, P.J., Komeluk, R.G. and Wieringa, B., Characterization of the myotonic dystrophy region predicts multiple protein isoform-encoding mRNAs, Nature Genet., 1 (1992) 261-266.
6. [6] Mahadevan, M.S., Amemiya, C.T., Jansen, G., Sabourin, L., Baird, S., Neville, C.E., Wormskamp, N., Segers, B., Lamerdin, J., de Jong, P., Wieringa, B. and Korneluk, R.G., Structure and genomic sequence of the myotonic dystrophy (DM kinase) gene, Hum. Mol. Genet., 2 (1993) 299-304.
7. [7] Mahadevan, M., Tsilfidis, C., Sabourin, L., Shuler, G., Amemiya, C., Jansen, G., Neville, C., Narang, M., Barcelo, J., O'Hoy, K., Leblond, S., Earle, J., de Jong, P.J., Wieringa, B. and Korneluk, R.G., Myotonic dystrophy mutation: an unstable CTG repeat in the 3′ untranslated region of the gene, Science, 255 (1992) 1253-1255.
8. [8] Mounsey, J.P., Xu, P., John, J.E., Horne, L.T., Gilbert, J., Roses, A.D. and Moorman, J.R., Modulation of skeletal muscle sodium channels by human myotonin protein kinase, J. Clin. Invest., 95 (1995) 2379-2384.
9. [9] Salvatori, S., Biral, D., Furlan, S. and Marin, O., Identification and localization of the myotonic dystrophy gene product in skeletal and cardiac muscles, Biochem. Biophys. Res. Commun., 203 (1994) 1365-1370.
10. [10] Sasagawa, N., Sorimatchi, H., Maruyama, K., Arahata, K., Ishiura, S. and Suzuki, K., Expression of a novel human myotonin protein kinase (MtPK) cDNA clone which encodes a protein with a thymopoietin-like domain in COS cells, FEBS Lett., 351 (1994) 22-26.
11. [11] Sasagawa, N., Saitoh, N., Shimokawa, M., Sorimatchi, H., Maruyama, K., Arahata, K., Ishiura, S. and Suzuki, K., Effect of artificial (CTG) repeat expansion on the expression of myotonin protein kinase (MtPK) in COS-1 cells, Biochim. Biophys. Acta, 1315 (1996) 112-116.
12. 2+ stores in myoblast fusion, Exp. Cell Res., 223 (1996) 301-307.
13. [13] Shaw, D.J., McCurrach, M., Rundle, S.A., Harley, H.G., Crow, S.R., Sohn, R., Thirion, J.-P., Hamshere, M.G., Buckler, A.J., Harper, P.S., Housman, D.E. and Brook, J.D., Genomic organization and transcriptional units at the myotonic dystrophy locus, Genomics, 18 (1993) 673-679.
14. [14] Timchenko, L., Nastainczyk, W., Schneider, T., Patel, B., Hofmann, F. and Caskey, C.T., Full-length myotonin protein kinase (72 kDa) displays serine kinase activity, Proc. Natl. Acad. Sci. USA, 92 (1995) 5366-5370.
15. [15] Van der Ven, P.F.M., Jansen, G., Van Kuppevelt, T.H.M.S.M., Perryman, M.B., Lupa, M., Dunne, P.W., Laak, H.J.T., Jap, P.H.K., Veerkamp, J.H., Epstein, H.F. and Wieringa, B., Myotonic dystrophy kinase is a component of neuromuscular junctions, Hum. Mol. Genet., 2 (1993) 1889-1894.