New cytostatic agents obtained by molecular topology

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 19, 1996, Pages 2301-2306

  Galvez, J ^a   Gomez Lechon M J ^b   Garcia Domenech R ^a   Castell, J V ^b  

^a UNIVERSITY OF VALENCIA   (Spain)

^b HOSPITAL UNIVERSITARIO LA FE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CARMINIC ACID; CLINDAMYCIN; CYTOSTATIC AGENT; DOXYCYCLINE; FLUOROURACIL; GENTAMICIN; MITOMYCIN C; PIROMIDIC ACID;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CULTURE; COMPUTER SIMULATION; CONTROLLED STUDY; DRUG DESIGN; DRUG STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; MATHEMATICS; TUMOR CELL;

EID: 0030575625     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00418-0     Document Type: Article

References (10)

1. 1. Kier, L.B.; Hall, L.H. In Molecular Connectivity in Structure-Activity Analysis, Research Study Press: Letchwoth, England, 1986; pp 225-246.
2. 2. Gálvez, J; Garcia, R; de Julian-Ortiz, V.J.; Soler, R; J. Chem. Inf. Comput. Sci., 1995, 35, 272-284.
3. 3. Kier, L.B.; Hall, L.H. In Molecular Connectivity in Chemistry and Drug Research, Academic Press: New York, 1976; pp 46-61.
4. 4. Collous, T In Discriminant Analysis and Applications, Academic Press: New York, 1973
5. 5. Carmichael J.; DeGraff W. G.; Gazdar A. F.; Minna J. D. and Mitchell J. B. Cancer Res., 1987, 47, 936-942.
6. 6. Ponsoda X.; Jover R.; Nuñez C.; Royo M.; Castell J. V. and Gómez-Lechón M. J. Toxic In Vitro 1995, 9, 959-996.
7. 7. Van der Bogert, C; Dontje, BH; Kroon, AM, Cancer Res., 1983, 43(5), 2247-2251.
8. 8. El Saghir. NS.; J Clin. Oncol., 1995, 13(3), 794-795.
9. 9. Fan, J.Y.; Sun-D; Yu-H et al.; J. Med. Chem., 1995, 38(3), 408-424.
10. 10. The Merck Index. Eleventh Edition. Merck & CO. Inc., Rahway, N.J. USA, 1989. pp 979 and 1192.