The mutagenicities of alkaloids and N-nitrosoguvacoline from betel quid

Mutation Research - Environmental Mutagenesis and Related Subjects

Volumn 360, Issue 3, 1996, Pages 165-171

  Wang, Chin Kun ^a   Peng, Chin Hui ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Ames Salmonella microsome test; Arecoline; Betel quid; N Nitrosoguvacoline

Indexed keywords

ALKALOID; ARECOLINE; NITRITE;

AMES TEST; ANIMAL TISSUE; ARTICLE; BETEL NUT; CONTROLLED STUDY; DOSE RESPONSE; METABOLIC ACTIVATION; MUTAGENICITY; NITROSATION; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030575552     PISSN: 01651161     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1161(96)90013-8     Document Type: Article

References (33)

1. Challis B.C. Rapid nitrosation of phenols and implications for health hazards from dietary nitrites. Nature. 244:1973;466.
2. Chen H.-C., Chang Y.-S., Lee T.-C. The mutagenicity of nitrite-treated aqueous extract of Piper betle L. Proc. Natl. Sci. Counc. ROC (B). 8:1984;4-10.
3. Dave B.J., Trivedi A.H., Adhvaryu S.G. In vitro genotoxic effects of areca nut extract and arecoline. J. Cancer Res. Clin. Oncol. 118:1992;283-288.
4. Grabowski J., Brown A., Bruza D., Stiaram N. Heart rate change following sleep infusion of arecoline. Psychiatry Res. 22:1987;261-262.
5. Lijinsky W., Taylor H.W. Carcinogenicity test of two unsaturated derivatives of N-nitropiperidine in Sprague-Dawley rats. J. Natl. Cancer Inst. 57:1976;1315-1317.
6. Magee P.N. In vivo reaction of nitroso compounds. Ann. NY Acad. Sci. 163:1969;717-725.
7. Maiese K., Holloway H.H., Larson D.M., Soncrant T.T. Effect of acute and chronic arecoline treatment on cerebral metabolism and blood flow in the consious rat. Brain Res. 641:1994;65-75.
8. Maron D.M., Ames B.N. Revised methods for the Salmonella mutagenicity test. Mutation Res. 113:1983;173-215.
9. Nagabhushan M., Amonkar A.J., Nair U.J., D'Souza A.V., Bhide S.V. Hydroxychavicol: a new anti-nitrosating phenolic compound from betel leaf. Mutagenesis. 4:1989;200-204.
10. Nair J., Ohshima H., Friesin M., Croisy A., Bhide S.V., Bartsch H. Tobacco-specific and betel nut specific N-nitroso compounds: occurrence in saliva and urine of betel quid chewers and formation in vitro by nitrosation of betel quid. Carcinogenesis. 6:1985;295-303.
11. Nicholas D.J., Nason A. Determination of nitrate and nitrite. Colowic S.P., Kaplan N.O. Methods of Enzymology. Vol. 3:1957;983 Academic Press, New York.
12. Nishikawa A., Prokopczky B., Rivenson A., Zang E., Hoffmann D. A study of betel quid carcinogenicity of 3-(methylnitrosamino)propionaldehyde in F344 rats. Carcinogenesis. 13:1992;369-372.
13. Nix C.E., Brewen B., Wilkerson R., Lijinsky W., Epler J.L. Effects on N-nitrosopiperidine substitutions on mutagenecity in Drosophila melanogaster. Mutation Res. 67:1979;27-38.
14. Panigrahi G.B., Rao A.R. Chromosome-breaking ability of arecoline, a major betel-nut alkaloid, in mouse bone-marrow cells in vivo. Mutation Res. 103:1982;197-204.
15. Pignatelli B., Friesen M., Walker E.A. The role of phenols in the catalysis of Nitrosamine formation. N-Nitroso Compounds: Analysis, Formation and Occurrence. Walker E.A., Castegnaro M., Griciute L., Borzsony M. Publication No. 31. 1980;96-106 IARC, Lyon.
16. Pignatelli B., Bereziat J.-C., Descotes G., Bartsch H. Catalysis of nitrosation in vitro and in vivo in rats by catechin and resorcinol and inhibition by chlorogenic acid. Carcinogenesis. 3:1982;1045-1049.
17. Prokopczky B., Rivnson A., Bertinato P., Brunnemann K.D., Hoffmann D. 3-(Methylnitrosamino)propionitrite: Occurrence in saliva of betel quid chewers, carcinogenicity, and DNA methylation in F344 rats. Cancer Res. 47:1987;467-471.
18. Prokopczky B., Rivnson A., Hoffmann D. A study of betel quid carcinogenesis IX. Comparative carcinogenicity of 3-(methylnitrosamino)propionitrile and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone upon local application to mouse skin and rat oral mucosa. Cancer Lett. 60:1991;153-157.
19. Rao T.K., Hardigree A.A., Young J.A., Lijinsky W., Epler J.L. Mutagenicity of N-nitrosopiperidines with Salmonella typhimurium/microsomal activation system. Mutation Res. 56:1977;131-145.
20. Rivenson A., Hoffmann D., Prokopczky B., Amin S., Hecht S. Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and Areca-derived N-nitrosamines . Cancer Res. 48:1988;6912-6917.
21. Shenoy N.R., Choughuley S.U. Effect of certain plant phenolics on nitrosamine formation. J. Agric. Food Chem. 37:1989;721-725.
22. Shirname L.P., Menon M.M., Nair J., Bhide S.V. Correlation of mutagenicity and tumorigenicity of betel quid and its ingredients. Nutr. Cancer. 5:1983;87-91.
23. Shirname L.P., Menon M.M., Bhide S.V. Mutagenicity of betel quid and its ingredients using mammalian test systems. Carcinogenesis. 5:1984;501-503.
24. Soncrant T.T., Raffaele K.C., Asthana S., Berardi A., Morris P.P., Haxby J.V. Memory improvement without toxicity during chronic, low dose intravenous arecoline in Alzheimer's disease. Psychopharmacology. 112:1993;421-427.
25. Stich H.F., Rosin M.P., Brunnemann K.D. Oral lesions, genotoxicity and nitrosamines in betel quid chewers with no obvious increase in oral cancer risk. Cancer Lett. 31:1986;15-25.
26. Walker E.A., Pignatelli B., Friesen M. The role of phenols in catalysis of nitrosamine formation. J. Sci. Food Agric. 33:1982;81-84.
27. Wang C.-K., Hwang L.S. Analysis of phenolic compounds in betel quid. J. Chinese Agric. Chem. Soc. 31:1993;623-632.
28. Wang C.-K., Hwang L.S. Study on the separation and hydrolysis of alkaloids from betel nut. Food Sci. 20:1993;514-526.
29. Wang C.-K., Hwang L.S. Phenolic compounds of betel quid chewing juice. Food Sci. 20:1993;458-471.
30. Wenke G., Hoffman D. A study of betel quid carcinogenesis. 1. On the in vitro N-nitrosation of arecoline. Carcinogenesis. 4:1983;169-172.
31. Wenke G., Brunnemann K.D., Hoffmann D., Bhide S.V. A study of betel quid carcinogenesis IV. Analysis of the saliva of betel chewers: A preliminary report. J. Cancer Res. Clin. Oncol. 108:1984;110-113.
32. Wenke G., Rivenson A., Hoffmann D. A study of betel quid carcinogenesis. 3. 3-(Methylnitrosamino)propionitrile, a powerful carcinogen in F344 rats. Carcinogenesis. 5:1984;1137-1140.
33. Yahagi T., Nagao M., Seino Y., Matsushima T., Sugimura T., Okada M. Mutagenicities of N-nitrosamines on Salmonella. Mutation Res. 48:1977;121-130.