Serotonergic effects on hypoglossal neural activity and reflex responses

Brain Research

Volumn 726, Issue 1-2, 1996, Pages 213-222

  Douse, M A ^a   White, D P ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Control of breathing; Decerebrate cat; Microinjection; Upper airway

Indexed keywords

METHYSERGIDE; SEROTONIN;

ANIMAL MODEL; ARTICLE; BREATHING; CAT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DECEREBRATION; FEMALE; HYPOGLOSSAL NERVE; HYPOGLOSSAL NUCLEUS; MALE; NERVE CONDUCTION; NONHUMAN; PRIORITY JOURNAL; REFLEX; UPPER RESPIRATORY TRACT; VAGOTOMY;

EID: 0030575323     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00335-6     Document Type: Article

References (57)

1. [1] Bellingham, M.C. and Lipski, J., Morphology and electrophysiology of superior laryngeal nerve afferents and post synpatic neurons in the medulla oblongata of the cat, Neuroscience, 48 (1992) 205-216.
2. [2] Berger, A.J., Bayliss, D.A. and Viana, F., Modulation of neonatal rat hypoglossal motoneuron excitability by serotonin, Neurosci. Lett., 143 (1992) 164-168.
3. [3] Bloom, F.E., The functional significance of neurotransmitter diversity, Am. J. Physiol., 246 (1984) C184-C194.
4. h in central neurons, Neuron, 2 (1989) 1535-1540.
5. [5] Cass, W.A. and Gerhardt, G.A., In vivo assessment of dopamine uptake in rat medial prefrontal cortex: comparison with dorsal striatum and nucleus accumbens, J. Neurochem., 65 (1995) 201-207.
6. [6] Crone, C., Hultborn, H., Kiehn, O., Mazieres, L. and Wigstrom, A., Maintained changes in motoneuronal excitablity by short-lasting synaptic inputs in the decerebrate cat, J. Physiol., 405 (1988) 321-343.
7. [7] Douse, M.A., Puglisi, EJ. and White. D.P., Serotonin in the dorsal respiratory group decreases hypoglossal (XII) neural activity, Soc. Neurosci. Abstr., 21 (1995) 1878.
8. [8] Eldridge, F.L., Gill-Kumar, P. and Millhorn, D.E., Input-output relationships of central neural circuits involved in respiration in cats, J, Physiol., 311 (1981) 81-95.
9. [9] Fornal, C.A. and Jacobs, B.L., Physiological and behavioral correlates of serotonergic single unit activity. In: N.N. Osborne and M. Hamon (Eds.), Neural Serotonin, Wiley, New York, NY, 1988, pp. 305-345.
10. [10] Goodman Gilman, A., Goodman, L.S., Gilman, A. (Eds.), Goodman and Gilman's The Pharmalogical Basis of Therapeutics, Sixth Edition, MacMillan, New York, NY, 1980.
11. [11] Heym, J., Steinfels, G.F. and Jacobs, B.L., Activity of serotonin-containing neurons in the nucleus raphe pallidus of freely moving cats, Brain Res., 251 (1982) 259-276.
12. [12] Holstege, J.C. and Kuypers, H.G.J.M., Brainstem projections to spinal motoneurons: an update, Neuroscience, 23 (1987) 809-821.
13. [13] Horner, R.L., Innes, J.A., Murphy, K. and Guz, A., Evidence for reflex upper airway dilator muscle activation by sudden negative airway pressure in man, J. Physiol. (Lond.), 436 (1993) 15-29.
14. [14] Horner, R.L., Innes, J.A., Morrell, J.M., Shea, S.A. and Guz, A., The effect of sleep on reflex genioglossus muscle activation by stimuli of negative airway pressure in humans. J. Physiol. (Lond.), 476 (1994) 141-151.
15. [15] Hoyer, D., Clarke, D.E., Fozard, J.R., Hartig, P.R., Martin, G.R., Mylecharane, E.J., Saxena, P.R. and Humphrey, P.P.A., International union of pharmacology classification of receptors for 5-hydroxytryptamine (serotonin), Pharm. Rev., 46 (1994) 157-203.
16. [16] Hwang, J., St. John, W.M. and Bartlett, D., Jr., Afferent pathways for hypoglossal and phrenic responses to changes in upper airway pressure, Respir. Physiol., 55 (1984) 341-354.
17. [17] Hwang, J., St. John, W.M. and Barlett, D., Jr., Respiratory-related hypoglossal nerve activity: influence of anesthetics, J. Appl. Physiol., 55 (1983) 785-792.
18. [18] Iscoe, S.D., Central control of the upper airway. In O.P. Mathew and G. Sant' Ambrogio (Eds.), Respiratory Function of the Upper Airway, Dekker, New York, NY, 1988, pp. 125-192.
19. [19] Jacobs, B.L. and Azmita, E.C., Structure and function of the brain serotonin system, Physiol. Rev., 72 (1992) 165-229.
20. [20] Jiang, C. and Lipski, J., Synaptic inputs to medullary respiratory neurons from superior laryngeal afferents in the cat, Brain Res., 584 (1992) 197-206.
21. [21] Jiang, C., Mitchell, G.S. and Lipski, J., Prolonged augmentation of respiratory discharge in hypoglossal motoneurons following superior laryngeal nerve stimulation, Brain Res., 538 (1991) 215-225.
22. [22] Kalia, M. and Mesulam, M., Brain stem projections of sensory and motor components of the vagus complex in the cat: II. laryngeal, tracheobronchial, pulmonary cardiac and gastrointestinal branches, J. Comp. Neurol., 193 (1980) 467-508.
23. [23] Kirsten, E.B. and St. John, W.M., A feline decerebration technique with low mortality and long-term homeostasis, J. Pharmacol. Meth., 1 (1978) 263-268.
24. [24] Kubin, L. and Davies, R.O., Central pathways of pulmonary and airway vagal afferents. In J.A. Dempsey and A.I. Pack (Eds.), Regulation of Breathing, Second Edition, Revised and Expanded, Dekker, New York, NY, 1995, pp. 219-284.
25. [25] Kubin, L., Reignier, C., Tojima, H., Taguchi, O., Pack, A.I. and Davies, R.O., Changes in serotonin level in the hypoglossal nucleus region during carbachol-induced atonia, Brain Res., 645 (1994) 291-302.
26. [26] Kubin, L., Tojima, H., Davies, R.O. and Pack, A.I., Serotonergic excitatory drive to hypoglossal motoneurons in the decerebrate cat. Neurosci. Lett., 139 (1992) 243-248.
27. [27] Laguzzi, R., Reis, D.J. and Talman, W.T., Modulation of cardiovascular and electrocortical activity through serotonergic mechanisms in the nucleus tractus solitarius of the rat, Brain Res., 304 (1984) 321-328.
28. [28] Lindsay, A.D. and Feldman, J.L., Modulation of respiratory activity of neonatal rat phrenic motoneurones by serotonin, J. Physiol. (Lond.), 261 (1993) 213-233.
29. [29] Lipski, J., Bellingham, M.C., West, M.J. and Pilowsky, P., Limitations of the technique of pressure microinjection of excitatory amino acids for evoking responses from localized regions of the CNS. J. Neurosci. Meth., 26 (1988) 169-179.
30. [30] Lucier, G.E., Egizii, R. and Dostrovsky, J.O., Projections of the internal branch of the superior laryngeal nerve of the cat, Brain Res. Bull., 16 (1985) 713-721.
31. [31] Mathew, O.P., Upper airway negative pressure effects on respiratory activity of upper airway muscles, J. Appl. Physiol., 56 (1984) 500.
32. [32] Mathew, O.P., Abu-Osba, Y.K. and Thach, B.T., Influence of upper airway pressure changes on genioglossus muscle and respiratory activity, J. Appl. Physiol., 52 (1982) 438.
33. [33] Mathew, O.P., Abu-Osba, Y.K. and Thach, B.T., Genioglossus muscle response to upper airway pressure changes: afferent pathways, J. Appl. Physiol., 52 (1982) 445.
34. [34] McCall, R.B. and Aghajanian, G.K., Serotonergic facilitaion of facial motoneuron excitation, Brain Res., 169 (1979) 11-27.
35. [35] McCrimmon, D.R., Dekin, M.S. and Mitchell, G.S., Glutamate, GABA and serotonin in ventilatory control. In J.A. Dempsey and A.I. Pack (Eds.), Regulation of Breathing, Second Edition, Lung Biology in Health and Disease, Vol. 79, Dekker, New York, NY, 1995, ch. 4, pp. 151-218.
36. [36] Mezzanotte, W.S., Tangel, D.J. and White, D.P., Waking genioglossal EMG in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism), J. Clin. Invest., 89 (1992) 1571-1579.
37. [37] Mitchell, G.S., Sloan, H.E., Jiang, C., Miletic, V., Hayashi, F. and Lipski, J., 5-Hydroxytryptophan (5-HTP) augments spontaneous and evoked phrenic motoneuron discharge in spinalized rats, Neurosci. Lett., 141 (1992) 75-78.
38. [38] Morin, D., Hennequin, S., Monteau, R. and Hilaire, G., Depressant effect of raphe stimulation on inspiratory activity of the hypoglossal nerve: in vitro study in the newborn rat, Neurosci. Lett., 116 (1990) 299-303.
39. [39] Morin, D., Monteau, R. and Hilaire, G., Compared effects of serotonin on cervical and hypoglossal inspiratory activities: an in vitro study in the newborn rat, J. Physiol. (Lond.), 451 (1992) 605-629.
40. [40] Onal, E., Lopata, M. and O'Connor, T., Pathogenesis of apnea in hypersomnia-sleep apnea syndrome, Am. Rec. Resp. Dis., 125 (1982) 167.
41. [41] Ono, T., Ishiwata, Y., Inaba, N., Kuroda, T. and Nakamura, Y., Hypoglossal premotor neurons with rhythmical inspiratory-related activity in the cat: localization and projection to the phrenic nucleus. Exp. Brain Res., 98 (1994) 1-12.
42. 3H]spiroperidol, Mol. Pharmacol., 16 (1979) 687-699.
43. [43] Remmers, J.E., DeGroot, W.J., Sauerland, E.K. and Anch, A.M., Pathogenesis of upper airway occlusion during sleep, J. Appl. Physiol., 44 (1978) 931.
44. [44] Ribeiro-do-Valle, L.E., Metzler, C.W. and Jacobs, B.L., Facilitaion of masseter EMG and masseteric (jaw-closure) reflex by serotonin in behaving cats, Brain Res., 550 (1991) 197-204.
45. [45] Richard, C.A. and Harper, R.M., Respiratory-related activity in hypoglossal neurons across sleep-waking states in cats, Brain Res., 543 (1991) 167-170.
46. [46] Schmid, K., Bohmer, G. and Merkelbach, S., Serotonergic control of phrenic motoneuronal activity at the level of the spinal cord of the rabbit, Neurosci. Lett., 116 (1990) 204-209.
47. [47] Stone, T.W., Microiontophoresis and Pressure Ejection, John Wiley and Sons, New York, NY, 1985.
48. [48] Takahashi, T. and Berger, A.J., Direct excitation of rat spinal motoneurones by serotonin, J. Physiol. (Lond.), 423 (1990) 63-76.
49. [49] Uemura, M., Matsuda, K., Kume, M., Takeuchi, Y., Matsushima, R. and Mizuno, N., Topographical arrangement of hypoglossal motoneurons: an HRP study in the cat. Neurosci. Lett., 13 (1979) 99-104.
50. [50] Van Vliet, B.N. and Uenishi, M., Antagonistic interaction of laryngeal and central chemoreceptor respiratory reflexes, J. Appl. Physiol., 72 (1992) 643-649.
51. [51] Wallis, D.I., 5HT receptors involved in initiation or modulation of motor patterns: opportunities for drug development, Trends Pharmacol. Sci., 15 (1994) 288-292.
52. [52] Wheatley, J.R., Mezzanotte, W.S., Tangel, D.J. and White, D.P., Influence of sleep on genioglossal muscle activation by negative pressure in normal men. Am. Rev. Respir. Dis., 148 (1993a) 597-605.
53. [53] Wheatley, J.R., Tangel D.J., Mezzanotte, W.S. and White, D.P., The influence of sleep on the response to negative pressure of the tensor palatini muscle and the retropalatal airway, J. Appl. Physiol., 75 (1993b) 2117-2124.
54. [54] White, S.R., A comparison of the effects of serotonin, substance P and thyrotropin-releasing hormone on excitability of rat spinal motoneurons in vivo. Brain Res., 33 (1995) 63-70.
55. [55] White, S.R. and Neuman, R.S., Facilitation of spinal motoneurone excitability by 5-hydroxytryptamine and noradrenaline, Brain Res., 188 (1980) 199-227.
56. [56] Wolf, W.A.: Kuhn, D.M. and Lovenberg, W., Blood pressure responses to local application of serotonerigc agents in the nuclues tractus solitarii, Eur. J. Pharmacol., 69 (1981) 291-299.
57. 2 on breathing pattern, J. Appl. Physiol., 65 (1988) 205-209.