Control analysis of single enzyme sequences with abortive complexes and random substrate binding

Journal of Theoretical Biology

Volumn 182, Issue 3, 1996, Pages 397-403

  Schulz, Arthur R ^a   Südi, Janos ^b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KIEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME;

AMINO ACID SEQUENCE; ENZYME BINDING; ENZYME KINETICS; ENZYME MECHANISM; ENZYME REGULATION; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL; REVIEW; STEADY STATE;

EID: 0030574111     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1006/jtbi.1996.0179     Document Type: Article

References (6)

1. BROWN, G. C. & COOPER, C. E. (1993). Control analysis applied to single enzymes: can an isolated enzyme have a unique rate-limiting step? Biochem. J. 294, 87-94.
2. BROWN, G. C. & COOPER, C. E. (1994). The analysis of rate limitation within enzymes: relations between flux, control coefficients of rate constants and thermodynamic parameters of single isolated enzymes. Biochem. J. 300, 159-164.
3. KHOLODENKO, B. N., WESTERHOFF, H. V. & BROWN, C. G. (1994). Rate limitation within a single enzyme is directly related to enzyme intermediate levels. FEBS Letters 349, 131-1134.
4. KHOLODENKO, B. N. & WESTERHOFF, H. V. (1994). Control theory of one enzyme. Biochim. Biophys. Acta 1207, 294-295.
5. SCHULZ, A. R. (1994). Enzyme Kinetics: From diastase to multi-enzyme systems, pp. 59-76, New York: Cambridge University Press.
6. SÜDI, J. (1996). How to derive flux control coefficients from the rate equations of classical enzyme kinetics. Math. Biosci (in press).