Stable quantitative EEG difference in post-LSD visual disorder by split-half analysis: Evidence for disinhibition

Psychiatry Research - Neuroimaging

Volumn 67, Issue 3, 1996, Pages 173-187

  Abraham, Henry David ^a,c   Duffy, Frank Hopkins ^b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BUTLER HOSPITAL   (United States)

Author keywords

electroencephalographic brain mapping; evoked potentials; hallucinogen persisting perceptual disorder

Indexed keywords

LYSERGIDE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROENCEPHALOGRAPHY; EVOKED RESPONSE; FEMALE; HALLUCINATION; HUMAN; MALE; PRIORITY JOURNAL; VISUAL DISORDER;

EID: 0030574055     PISSN: 09254927     EISSN: None     Source Type: Journal    
DOI: 10.1016/0925-4927(96)02833-8     Document Type: Article

References (56)

1. Abraham, H.D. (1982) A chronic impairment of colour vision in users of LSD. Br J Psychiatry 140, 518-520.
2. Abraham, H.D. (1983) Visual phenomenology of the LSD flashback. Arch Gen Psychiatry 40, 884-889.
3. Abraham, H.D. and Duffy, F.H. (1991) Computed EEG abnormalities in panic disorder with and without premorbid drug abuse. Biol Psychol 29, 687-690.
4. Abraham, H.D. and Gogia, P. The hallucinogens. In: Schuckit, M. et al. (Eds.), Bailliere's Textbook of Psychiatry. In press.
5. Abraham, H.D. and Wolf, E. (1988) Visual function in past users of LSD: psychophysical findings. J Abnorm Psychol 97, 443-447.
6. Abt, K. (1981) Problems of repeated significance testing. Control Clin Trials 1, 377-381.
7. Abt, K. (1983) Significance testing of many variables - problems and solutions. Neuropsychobiology 9, 47-51.
8. Aghajanian, G.K., Foote, W.E. and Sheard, M.H. (1968) Lysergic acid diethylamide: sensitive neuronal units in the midbrain raphe. Science 161, 706-708.
9. Bradley, P.B. and Elkes, J. (1953) Effect of amphetamine and LSD-25 on electrical activity of the brain in the conscious cat. J Physiol 120, 13P.
10. Brawley, P. and Duffield, J.C. (1972) The pharmacology of hallucinogens. Pharmacol Rev 24, 31-66.
11. Cooper, H.A. (1955) Hallucinogenic drugs. Lancet 268, 1078-1079.
12. Delay, J.F., L'Hermitte, G. and Verdeaux, J. (1952) Modifications de l'electrocorticograms du lapin par la diethylamide de l'acide d-lysergide (LSD-25). Rev Neurol 86, 81-88.
13. Dixon, W.J. (Ed.) (1988) BMDP Statistical Software Manual. University of California Press, Berkeley, CA.
14. Duffy, F.H. (1988) Clinical decision making in quantified electroencephalographic analysis. In: Samson-Dollfus, D., Gotman, J., Guieu, J.D. and Etevenon, P. (Eds.), Statistics and Topography in Quantitative EEG. Elsevier, Amsterdam, pp. 9-26.
15. Duffy, F.H., Albert, M.S., McAnulty, G. and Garvey, A.J. (1984) Age-related differences in brain electrical activity of healthy subjects. Ann Neurol 16, 430-438.
16. Duffy, F.H., Bartels, P.M. and Burchfiel, J.L. (1981) Significance probability mapping: an aid in the topographic analysis of brain electrical activity. Electroencephalogr Clin Neurophysiol 51, 455-462.
17. Duffy, F.H., Burchfiel, J.L. and Lombroso, C.T. (1979) Brain electrical activity mapping (BEAM): a method for extending the clinical utility of EEG and evoked potential data. Ann Neurol 5, 309-321.
18. Duffy, F.H., Denckla, M.B., Bartels, P.H. and Sandini, G. (1980) Dyslexia: regional differences in brain electrical activity by topographic mapping. Ann Neurol 7, 412-420.
19. Duffy, F.H., Jones, K., Bartels, P., Albert, M., McAnulty, G.B. and Als, H. (1990) Quantified neurophysiology with mapping: statistical inference, exploratory and confirmatory data analysis [Review]. Brain Topogr 3, 3-12.
20. Duffy, F.H., Jones, K.H., McAnulty, G.B. and Albert, M.S. (1992) Unresticted principal components analysis of brain electrical activity: issues of data dimensionality, artifact, and utility. Brain Topogr 4, 291-307.
21. Duffy, F.H., Jones, K.H., McAnulty, G.B. and Albert, M.S. (1995) Spectral coherence in normal adults: unrestricted principal components analysis - relation of factors to age, gender, and neuropsychologic data. Clin Electroencephalogr 26, 30-46.
22. Duffy, F.H. and McAnulty, G.B. (1988) Electrophysiological studies. In: Albert, M.S. and Moss, M. (Eds.), Neuroimaging and Cognition. Gilford Press, New York, pp. 262-289.
23. Duffy, F.H.. McAnulty, G.B. and Albert, M.S. (1993a) The pattern of age-related differences in electrophysiological activity of healthy males and females. Neurobiol Aging 14, 73-84.
24. Duffy, F.H., McAnulty, G.B., Jones, K., Als, H. and Albert, M. (1993b) Brain electrical correlates of psychological measures: strategies and problems. Brain Topogr 5, 399-412.
25. Foley, D.H. (1972) Consideration of sample and feature size. IEEE Trans Inform Theory IT-18, 618-626.
26. Garratt, J.C., Alreja, M. and Aghajanian, G.K. (1993) LSD has high efficacy relative to serotonin in enhancing the cationic current Ih: intracellular studies in rat facial motoneurons. Synapse 13, 123-134.
27. Gasser, T., Bacher, P. and Mocks, J. (1982) Transformations towards the normal distribution of broad band spectral parameters of the EEG. Electroencephalogr Clin Neurophysiol 53, 119-124.
28. Gastaut, H., Ferrer, S. and Castella, C. (1953) Action de la diethylamide de l'acide d-lysergide (LSD-25) sur les fonctions psychiques et l'electroencephalogramme. Confin Neurol 13, 102-120.
29. Glennon, R.A., Titeler, M. and McKenney, J.D. (1984) Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents. Life Sci 35, 2505-2511.
30. Hollister, L. (1962) Drug induced psychoses and schizophrenic reactions: a critical comparison. Ann NY Acad Sci 80-92.
31. Holsten, F. (1976) Flashbacks. Clinical and social significance 1 1/2-4 years after the 1st admission [Norwegian]. Tidsskr Nors Laegeforen 96, 875-878.
32. Horowitz, M.J. (1969) Flashbacks: recurrent intrusive images after the use of LSD. Am J Psychiatry 126, 565-569.
33. Hughes, J.R. (1982) EEG in Clinical Practice. Butterworth, Boston.
34. Hughes, J.R. and Olson, S.F. (1981) An investigation of eight different types of temporal lobe discharges. Epilepsia 22, 421-435.
35. Itil, T. and Fink, M. (1968) Anticholinergic hallucinogens and their interaction with centrally active drugs. Prog Brain Res 28, 149-168.
36. John, E.R., Prichep, L.S., Fridman, J. and Easton, P. (1988) Neurometrics: computer-assisted differential diagnosis of brain dysfunctions. Science 239, 162-169.
37. Johnston, L., O'Malley, P. and Bachman, J. (1993) National Survey Results on Drug Use from Monitoring the Future Study, 1975-1992. (NIH Pub. No. 93-3597). National Institute on Drug Abuse, Rockville, MD.
38. Koella, W.P. and Wells, C.H. (1959) Influence of LSD-25 on optically evoked potentials in the nonanesthetized rabbit. Am J Physiol 196, 1181-1184.
39. Krill, A.E., Alpert, H.J. and Ostfield, A.M. (1963) Effects of a hallucinogenic agent in totally blind subjects. Arch Ophthalmol 69, 180-185.
40. Lachenbruch, P. and Mickey, R.M. (1968) Estimation of error rates in discriminant anaylsis. Technomet 10, 1-11.
41. Matejcek, M., Blasowitsch, R., Schweingruber, M. and Abt, K. (1986) Some correlations in geriatric patients between EEG parameters and clinical status as evaluated using the observer-rated SCAG rating scale. A retrospective study. Neuropsychobiology 15, 49-56.
42. Maus, A. and Endresen, J. (1979) Misuse of computer-generated results. Med Biol Eng Comput 17, 126-129.
43. McCall, R.B. (1986) Effects of hallucinogenic drugs on serotonergic neuronal systems. Pharmacol Biochem Behav 24, 359-363.
44. McCarley, R.W., Shenton, M.E., O'Donnell, B.F., Faux, S.F., Kikinis, R., Nestor, P.G. and Jolesz, F.A. (1993) Auditory P300 abnormalities and left posterior superior temporal gyrus volume reduction in schizophrenia. Arch Gen Psychiatry 50, 190-197.
45. Morihisa, J.M., Duffy, F.H. and Wyatt, R.J. (1983) Brain electrical activity mapping (BEAM) in schizophrenic patients. Arch Gen Psychiatry 40, 719-728.
46. Pazos, A., Cortes, R. and Palacios, J.M. (1985) Quantitative autoradiographic mapping of serotonin receptors in the rat brain. II. Serotonin-2 receptors. Brain Res 346, 231-249.
47. Pollock, V.E., Schneider, L.S. and Lyness, S.A. (1990) EEG amplitudes in healthy, late-middle-aged and elderly adults: normality of the distributions and correlations with age. Electroencephalogr Clin Neurophysiol 75, 276-288.
48. Rebert, C.S. (1978) Neuroelectric measures of lateral specialization in relation to performance. Electroencephalogr Clin Neurophysiol 34 (Suppl). 231-238.
49. Rinkel, M., Deshon, H.J., Hyde, R.W. and Solomon, H.C. (1952) Experimental schizophrenia-like symptoms. Am J Psychiatry 108, 572-578.
50. Robbins, E., Frosch, W.A. and Stern, M. (1967) Further observations on untoward reactions to LSD. Am J Psychiatry 124, 393-395.
51. Rosenthal, S.H. (1964) Persistent hallucinosis following repeated administration of hallucinogenic drugs. Am J Psychiatry 121, 238-244.
52. Savage, C.R., Weilburg, J.B., Duffy, F.H., Baer, L., Shera, D.M. and Jenike, M.A. (1994) Low-level sensory processing in obsessive-compulsive disorder: an evoked potential study. Biol Psychol 35, 247-252.
53. Sheldon, P.W. and Aghajanian, G.K. (1990) Serotonin (5-HT) induces IPSPs in pyramidal layer cells of rat piriform cortex: evidence for the involvement of a 5-HT2-activated interneuron. Brain Res 506, 62-69.
54. Skalka, H. and Holman, J. (1986) Effect of pupillary dilatation in flash VER testing. Doc Ophthalmol 63, 321-324.
55. Wright, S. (1921) Correlation and causation. J Agric Res 20, 557-585.
56. Zar, J.H. (1984) Biostatistical Analysis. Prentice Hall, Englewood Cliffs, NJ.