Loop mutations affect ferritin solubility causing non-native aggregation of subunits or precipitation of fully assembled polymers

FEBS Letters

Volumn 394, Issue 3, 1996, Pages 311-315

  Jappelli, Roberto ^a,b   Cesareni, Gianni ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b The Molecular Sciences Institute   (United States)

Author keywords

Aggregation; Ferritin; Inclusion body; Loop; Protein assembly; Protein folding

Indexed keywords

FERRITIN;

AMINO ACID SUBSTITUTION; ARTICLE; ESCHERICHIA COLI; GENE EXPRESSION; HUMAN; MUTATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FOLDING; SOLUBILITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0030574045     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(96)00979-9     Document Type: Article

References (20)

1. [1] Jaenicke, R. (1987) Progr. Biophys. Mol. Biol. 49, 117-237.
2. [2] Jaenicke, R. (1991) Biochemistry. 30, 3147-3161.
3. [3] Ford, G.C., Harrison, P.M, Rice, D.W., Smith, J.M.A., Treffry, A., White, J.L. and Yariv, J. (1984) Phil. Trans. Roy. Soc. Lond. B 304, 551-565.
4. [4] Costanzo, F., Santoro, C., Colantuoni, V., Bensi, G., Raugei, G., Romano, V. and Cortese, R. (1984) EMBO J. 3, 23-27.
5. [5] Levi, S., Cesareni, G., Arosio, P., Lorenzetti, R., Soria, M., Sollazzo, M., Albertini, A. and Cortese, R. (1987) Gene 51, 269-274.
6. [6] Lawson, D.M., Artymiuk, P.J., Yewdall, S.J., Smith, J.M.A., Livingstone, J.C., Treffry, A., Luzzago, A., Levi, S., Arosio, P., Cesareni, G., Thomas, C.D., Shaw, W.V.and Harrison, P.M. (1991) Nature 349, 541-544.
7. [7] Stefanini, S., Vecchini, P. and Chiancone, E. (1987) Biochemistry 26, 1831-1837.
8. [8] Gerl, M. and Jaenicke, R. (1988) Biochemistry 27, 4089-4096.
9. [9] Santambrogio, P., Levi, S., Arosio, P., Palagi, L., Vecchio, G., Lawson, D.M., Yewdall, S.J., Artymiuk, PJ., Harrison, P.M., Jappelli, R. and Cesareni, G. (1992) J. Biol. Chem. 267, 14077-14083.
10. [10] Douglas, T., Dickson, D.P.E., Betteridge, S., Charnock, J., Garner, C.D. and Mann, S. (1995) Science 269, 54-57.
11. [11] Jappelli, R., Luzzago, A., Tataseo, P., Pernice, I. and Cesareni, G. (1992) J. Mol. Biol. 227, 532-543.
12. [12] Luzzago, A. and Cesareni, G. (1989) EMBO J. 8, 569-576.
13. [13] Laemmli, U.K. (1970) Nature, 227, 680-685.
14. [14] Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989). Molecular Cloning, A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
15. [15] Kunkel, T.A., Roberts, J.D. and Zakour. R.A. (1987) Methods Enzymol. 153, 367-382.
16. [16] Marston, F.A.O. and Hartley, D.L. (1990) Methods Enzymol. 182, 264-276.
17. [17] Marston, F.A.O. (1986) Biochem. J. 240, 1-12.
18. [18] Schein, C.H. (1989) Biotechnology 7, 1141-1149.
19. [19] Kiefhaber, T., Rudolph, R., Kohler, H.-H. and Buchner, J. (1991) Biotechnology 9, 825-829.
20. [20] Wetzel, R. (1994) TIBTECH 12, 193-198.