-
1
-
-
77049220618
-
Affinity and intrinsic activity in the theory of competitive inhibition
-
ARIËNS, E. J. (1954). Affinity and intrinsic activity in the theory of competitive inhibition. Arch. Int. Pharmacodynamie Therapie 99, 32-49.
-
(1954)
Arch. Int. Pharmacodynamie Therapie
, vol.99
, pp. 32-49
-
-
Ariëns, E.J.1
-
2
-
-
0011804582
-
Affinity and intrinsic-activity in the theory of competitive inhibition. Part III. Homologous decamethonium-derivatives and succinyl-cholineesters
-
ARIËNS, E. J. & DE GROOT, W. M. (1954). Affinity and intrinsic-activity in the theory of competitive inhibition. Part III. Homologous decamethonium-derivatives and succinyl-cholineesters. Arch. Intern. Pharmacodynamie Therapie 99, 193-205.
-
(1954)
Arch. Intern. Pharmacodynamie Therapie
, vol.99
, pp. 193-205
-
-
Ariëns, E.J.1
De Groot, W.M.2
-
3
-
-
0011876812
-
Affinity and intrinsic-activity in the theory of competitive-and noncompetitive inhibition and analysis of some forms of dualism in action
-
ARIËNS, E. J., SIMONIS, A. M. & DE GROOT, W. M. (1955). Affinity and intrinsic-activity in the theory of competitive-and noncompetitive inhibition and analysis of some forms of dualism in action. Arch. Int. Pharmacodynamie Therapie 100, 298-322.
-
(1955)
Arch. Int. Pharmacodynamie Therapie
, vol.100
, pp. 298-322
-
-
Ariëns, E.J.1
Simonis, A.M.2
De Groot, W.M.3
-
5
-
-
0001341484
-
A theoretical basis of molecular pharmacology. Part II: Interactions of one or two compounds with two interdependent receptor systems
-
ARIËNS, E. J., VAN ROSSUM, J. M. & SIMONIS, A. M. (1956a). A theoretical basis of molecular pharmacology. Part II: Interactions of one or two compounds with two interdependent receptor systems. Arzneimittel-Forsch. 6, 611-621.
-
(1956)
Arzneimittel-forsch.
, vol.6
, pp. 611-621
-
-
Ariëns, E.J.1
Van Rossum, J.M.2
Simonis, A.M.3
-
6
-
-
9044226653
-
A theoretical basis of molecular pharmacology, part III
-
ARIËNS, E. J., VAN ROSSUM, J. M. & SIMONIS, A. M. (1956b). A theoretical basis of molecular pharmacology, part III. Arzneimittel-Forsch. 6, 737-746.
-
(1956)
Arzneimittel-Forsch.
, vol.6
, pp. 737-746
-
-
Ariëns, E.J.1
Van Rossum, J.M.2
Simonis, A.M.3
-
7
-
-
0004198357
-
Drug-receptor interaction: Interaction of one or more drugs with one receptor system
-
Ariëns, E. J., ed. New York: Academic Press
-
ARIËNS, E. J., SIMONIS, A. M. & VAN ROSSUM, J. M. (1964a). Drug-receptor interaction: Interaction of one or more drugs with one receptor system. In: Molecular Pharmacology, Vol. I (Ariëns, E. J., ed), pp. 119-286. New York: Academic Press.
-
(1964)
Molecular Pharmacology
, vol.1
, pp. 119-286
-
-
Ariëns, E.J.1
Simonis, A.M.2
Van Rossum, J.M.3
-
8
-
-
0000457493
-
Drug-receptor interaction: Interaction of one or more drugs with different receptor systems
-
Ariëns, E. J., ed. New York: Academic Press
-
ARIËNS, E. J., SIMONIS, A. M. & VAN ROSSUM, J. M. (1964b). Drug-receptor interaction: Interaction of one or more drugs with different receptor systems, in Molecular Pharmacology, Vol. I (Ariëns, E. J., ed), pp. 287-393. New York: Academic Press.
-
(1964)
Molecular Pharmacology
, vol.1
, pp. 287-393
-
-
Ariëns, E.J.1
Simonis, A.M.2
Van Rossum, J.M.3
-
9
-
-
0000161089
-
Receptor theory and structure activity relationships
-
Harper N. J. & Simmonds, A. B., eds. London: Academic Press
-
ARIËNS, E. J. (1966). Receptor theory and structure activity relationships. In: Advances in Drug Research (Harper N. J. & Simmonds, A. B., eds) pp. 235-285. London: Academic Press.
-
(1966)
Advances in Drug Research
, pp. 235-285
-
-
Ariëns, E.J.1
-
11
-
-
0021058380
-
Operational models of pharmacological agonism
-
BLACK, J. W. & LEFF, P. (1983). Operational models of pharmacological agonism. Proc. R. Soc. Lond. B 220, 141-162.
-
(1983)
Proc. R. Soc. Lond. B
, vol.220
, pp. 141-162
-
-
Black, J.W.1
Leff, P.2
-
12
-
-
0002838483
-
Drug receptors and pharmacodynamics
-
Katzung, B. G., ed. Norwalk, CN: Appleton & Lange
-
BOURNE, H. R. & ROBERTS, J. M. (1995). Drug receptors and pharmacodynamics. In: Basic and Clinical Pharmacology - Sixth edition (Katzung, B. G., ed) pp. 9-32. Norwalk, CN: Appleton & Lange.
-
(1995)
Basic and Clinical Pharmacology - Sixth Edition
, pp. 9-32
-
-
Bourne, H.R.1
Roberts, J.M.2
-
13
-
-
0002060353
-
The relation between classical and cooperative models for drug action
-
Rang H. P., ed. London: Academic Press
-
COLQUHOUN, D. (1972). The relation between classical and cooperative models for drug action, in Drug Receptors (Rang H. P., ed) pp. 149-182. London: Academic Press.
-
(1972)
Drug Receptors
, pp. 149-182
-
-
Colquhoun, D.1
-
14
-
-
0024821010
-
2 receptor agonists in the treatment of Schizophrenia
-
2 receptor agonists in the treatment of Schizophrenia. Psychopharmacol. Bull. 25, 393-397.
-
(1989)
Psychopharmacol. Bull.
, vol.25
, pp. 393-397
-
-
Coward, D.1
Dixon, K.2
Albert, E.3
Shearman, G.4
Urwyler, S.5
White, T.6
Karobath, M.7
-
15
-
-
0026659149
-
Relationship between benzodiazepine receptor occupancy and functional effects in vivo of four ligands of differing intrinsic efficacies
-
FACKLAM, M., SCHOCH, P., BONETTI, E. P., JENCK, F., MARTIN, J. R., MOREAU, J-L. & HAEFELY, W. E. (1992). Relationship between benzodiazepine receptor occupancy and functional effects in vivo of four ligands of differing intrinsic efficacies. J. Pharmacol. Exp. Ther. 261, 1113-1121.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.261
, pp. 1113-1121
-
-
Facklam, M.1
Schoch, P.2
Bonetti, E.P.3
Jenck, F.4
Martin, J.R.5
Moreau, J.-L.6
Haefely, W.E.7
-
16
-
-
0002355204
-
The use of α-haloalkylamines in the differentiation of receptors and in the determination of dissociation constants of receptor-agonist complexes
-
FURCHGOTT, R. F. (1966). The use of α-haloalkylamines in the differentiation of receptors and in the determination of dissociation constants of receptor-agonist complexes. Adv. Drug Res. 3, 21-55.
-
(1966)
Adv. Drug Res.
, vol.3
, pp. 21-55
-
-
Furchgott, R.F.1
-
17
-
-
84981848149
-
Comparison of dissociation constants and relative efficacies of selected agonists acting on parasympathetic receptors
-
FURCHGOTT, R. F. & BURSZTYN, P. (1967). Comparison of dissociation constants and relative efficacies of selected agonists acting on parasympathetic receptors. Ann. N. Y. Acad. Sci. 144, 882-898.
-
(1967)
Ann. N. Y. Acad. Sci.
, vol.144
, pp. 882-898
-
-
Furchgott, R.F.1
Bursztyn, P.2
-
18
-
-
0023746646
-
Xamoterol: A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use
-
FURLONG, R. & BROGDEN, R. N. (1988). Xamoterol: A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use. Drugs 36, 455-474.
-
(1988)
Drugs
, vol.36
, pp. 455-474
-
-
Furlong, R.1
Brogden, R.N.2
-
19
-
-
0025043989
-
Novel anxiolytics that act as partial agonists at benzodiazepine receptors
-
HAEFELY, W., MARTIN, J. R. & SCHOCH, P. (1990). Novel anxiolytics that act as partial agonists at benzodiazepine receptors. TiPS 11, 452-456.
-
(1990)
TiPS
, vol.11
, pp. 452-456
-
-
Haefely, W.1
Martin, J.R.2
Schoch, P.3
-
20
-
-
0023276499
-
Pharmacological analysis of the cardiac actions of Xamoterol, a beta adrenoceptor antagonist with partial agonistic activity, in Guinea pig heart: Evidence for involvement of adenylate cyclase system in its cardiac stimulant actions
-
HOTTORI, Y., SAKUMA, I., NAKAO, Y. & KANNO, M. (1987). Pharmacological analysis of the cardiac actions of Xamoterol, a beta adrenoceptor antagonist with partial agonistic activity, in Guinea pig heart: Evidence for involvement of adenylate cyclase system in its cardiac stimulant actions. J. Pharmacol. Exp. Ther. 242, 1077-1085.
-
(1987)
J. Pharmacol. Exp. Ther.
, vol.242
, pp. 1077-1085
-
-
Hottori, Y.1
Sakuma, I.2
Nakao, Y.3
Kanno, M.4
-
21
-
-
0021321714
-
The effects of beta1-adrenoceptor partial agonist ICI 118,587 on left ventricular function in patients with coronary heart disease
-
IKÄHEIMO, M. J. & TAKKUNEN, J. T. (1984). The effects of beta1-adrenoceptor partial agonist ICI 118,587 on left ventricular function in patients with coronary heart disease. Int. J. Cardiol. 5, 339-351.
-
(1984)
Int. J. Cardiol.
, vol.5
, pp. 339-351
-
-
Ikäheimo, M.J.1
Takkunen, J.T.2
-
22
-
-
0021215468
-
Cardioselective, kinetics, hemodynamics, and metabolic effects of xamoterol
-
JENNINGS, G., BOBIK, A., ODDIE, C. & RESTALL, R. (1984). Cardioselective, kinetics, hemodynamics, and metabolic effects of xamoterol. Clin. Pharmacol. Ther. 35, 594-603.
-
(1984)
Clin. Pharmacol. Ther.
, vol.35
, pp. 594-603
-
-
Jennings, G.1
Bobik, A.2
Oddie, C.3
Restall, R.4
-
23
-
-
0021211721
-
The classification of drugs and drug receptors in isolated tissues
-
KENAKIN T. P. (1984). The classification of drugs and drug receptors in isolated tissues. Pharmacol. Rev. 36, 165-222.
-
(1984)
Pharmacol. Rev.
, vol.36
, pp. 165-222
-
-
Kenakin, T.P.1
-
24
-
-
0021808471
-
The quantification of relative efficacy of agonists
-
KENAKIN T. P. (1985). The quantification of relative efficacy of agonists. J. Pharmacol. Methods 13, 281-308.
-
(1985)
J. Pharmacol. Methods
, vol.13
, pp. 281-308
-
-
Kenakin, T.P.1
-
26
-
-
0011883711
-
Pharmakologische eigenschaften einiger langwirksamer cholinesterase-hemmkörper aus der reihe der polymethylen-bis-carbaminoyl-m-trimethylammoniumphenole
-
KRAUPP, O., STUMPF, C., HERZFELD, E. & PILLAT, U. B. (1955). Pharmakologische eigenschaften einiger langwirksamer cholinesterase-hemmkörper aus der reihe der polymethylen-bis-carbaminoyl-m-trimethylammoniumphenole. Arch. Int. Pharmacodynamie Therapie 102, 281-303.
-
(1955)
Arch. Int. Pharmacodynamie Therapie
, vol.102
, pp. 281-303
-
-
Kraupp, O.1
Stumpf, C.2
Herzfeld, E.3
Pillat, U.B.4
-
27
-
-
0021831787
-
1-adrenoceptor partial agonist, on resting haemodynamic variables and exercise tolerance in patients with left ventricular dysfunction
-
1-adrenoceptor partial agonist, on resting haemodynamic variables and exercise tolerance in patients with left ventricular dysfunction. Br. Heart J. 54, 17-21.
-
(1985)
Br. Heart J.
, vol.54
, pp. 17-21
-
-
Molajo, A.O.1
Bennett, D.H.2
-
29
-
-
0011883902
-
Steric aspects of adrenergic drugs. II. Effects of dl-isomers and desoxy derivatives on the reserpine-pretreated vas deferens
-
PATIL, P. N., LAPIDUS, J. B. & TYE, A. (1967). Steric aspects of adrenergic drugs. II. Effects of dl-isomers and desoxy derivatives on the reserpine-pretreated vas deferens. J. Pharmacol. Exp. Ther. 115, 1-12.
-
(1967)
J. Pharmacol. Exp. Ther.
, vol.115
, pp. 1-12
-
-
Patil, P.N.1
Lapidus, J.B.2
Tye, A.3
-
30
-
-
0020451569
-
Opioid agonist and antagonist bivalent ligands as receptor probes
-
PORTOGHESE, P. S., RONSISVALLE, G., LARSON, D. L., YIM, C. B., SAYRE, L. M. & TAKEMORI, A. E. (1982). Opioid agonist and antagonist bivalent ligands as receptor probes. Life Sci. 31, 1280-1286.
-
(1982)
Life Sci.
, vol.31
, pp. 1280-1286
-
-
Portoghese, P.S.1
Ronsisvalle, G.2
Larson, D.L.3
Yim, C.B.4
Sayre, L.M.5
Takemori, A.E.6
-
31
-
-
0022251438
-
Stereostructure-activity relationship of opioid agonist and antagonist bivalent ligands. Evidence for bridging between vicinal opioid receptors
-
PORTUGESE, P. S., LARSON, D. L., YIM, C. B., SAYRE, L. M., RONSISVALLE, G., LIPKOWSKI, A. W., ET AL. (1985). Stereostructure-activity relationship of opioid agonist and antagonist bivalent ligands. Evidence for bridging between vicinal opioid receptors. J. Med. Chem. 28, 1140-1141.
-
(1985)
J. Med. Chem.
, vol.28
, pp. 1140-1141
-
-
Portugese, P.S.1
Larson, D.L.2
Yim, C.B.3
Sayre, L.M.4
Ronsisvalle, G.5
Lipkowski, A.W.6
-
32
-
-
0020453745
-
1 adrenoceptor partial agonist, ICI 118,587
-
1 adrenoceptor partial agonist, ICI 118,587. Eur. Heart J. 3 (suppl. D), 123-127.
-
(1982)
Eur. Heart J.
, vol.3
, Issue.SUPPL. D
, pp. 123-127
-
-
Pouleur, H.1
Rousseau, M.F.2
Mengeot, P.3
Veriter, C.4
Vincent, M.F.5
-
33
-
-
0020583609
-
1 partial agonist (Corwin) on left ventricular function and myocardial infarction
-
1 partial agonist (Corwin) on left ventricular function and myocardial infarction. Am. J. Cardiol. 51, 1267-1274.
-
(1983)
Am. J. Cardiol.
, vol.51
, pp. 1267-1274
-
-
Rousseau, M.F.1
Pouleur, H.2
Vincent, M.-F.3
-
34
-
-
0003218218
-
Endocrine systems: Mechanisms of disease, target cells, and receptors
-
Williams R. H., ed, Philadelphia: W. B. Saunders Co
-
ROTH, J. & GRUNFELD, C. (1981). Endocrine systems: mechanisms of disease, target cells, and receptors. In: Textbook of Endocrinology, sixth edition (Williams R. H., ed), Philadelphia: W. B. Saunders Co.
-
(1981)
Textbook of Endocrinology, Sixth Edition
-
-
Roth, J.1
Grunfeld, C.2
-
35
-
-
0018360305
-
Receptor interactions of imidazolines. I. Affinity and efficacy for α-adrenergic receptors in rat aorta
-
RUFFOLO, R. R., ROSING, E. L. & WADDEL, J. E. (1979). Receptor interactions of imidazolines. I. Affinity and efficacy for α-adrenergic receptors in rat aorta. J. Pharmacol. Exp. Ther. 209, 429-436.
-
(1979)
J. Pharmacol. Exp. Ther.
, vol.209
, pp. 429-436
-
-
Ruffolo, R.R.1
Rosing, E.L.2
Waddel, J.E.3
-
36
-
-
0018903858
-
Receptor interactions of imidazolines. IV. Structural requirements for alpha adrenergic receptor occupation and receptor activation by clonidine and a series of structural analogs in rat aorta
-
RUFFOLO, R. R., WADDELL, J. E. & YADEN, E. L. (1980). Receptor interactions of imidazolines. IV. Structural requirements for alpha adrenergic receptor occupation and receptor activation by clonidine and a series of structural analogs in rat aorta. J. Pharmacol. Exp. Ther. 213, 267-272.
-
(1980)
J. Pharmacol. Exp. Ther.
, vol.213
, pp. 267-272
-
-
Ruffolo, R.R.1
Waddell, J.E.2
Yaden, E.L.3
-
37
-
-
0019984467
-
Receptor interactions of imidazolines: α-adrenoceptors of rat and rabbit aortae differentiated by relative potencies, affinities and efficacies of imidazoline agonists
-
RUFFOLO, R. R. & WADDELL, J. E. (1982). Receptor interactions of imidazolines: α-adrenoceptors of rat and rabbit aortae differentiated by relative potencies, affinities and efficacies of imidazoline agonists. Br. J. Pharmacol. 77, 169-176.
-
(1982)
Br. J. Pharmacol.
, vol.77
, pp. 169-176
-
-
Ruffolo, R.R.1
Waddell, J.E.2
-
38
-
-
0025572437
-
1-adrenoceptor partial agonist treatment for congestive heart failure
-
1-adrenoceptor partial agonist treatment for congestive heart failure. Cardiology 77, 357-366.
-
(1990)
Cardiology
, vol.77
, pp. 357-366
-
-
Shabetai, R.1
-
39
-
-
0020078940
-
Dimeric enkephalins display enhanced affinity and selectivity for the delta opiate receptor
-
SHIMOHIGASHI, Y., COSTA, T., MATSUURA, S., CHEN, H.-C. & RODBARD, D. (1982). Dimeric enkephalins display enhanced affinity and selectivity for the delta opiate receptor. Mol. Pharmacol. 21, 558-563.
-
(1982)
Mol. Pharmacol.
, vol.21
, pp. 558-563
-
-
Shimohigashi, Y.1
Costa, T.2
Matsuura, S.3
Chen, H.-C.4
Rodbard, D.5
-
40
-
-
0010673662
-
A modification of receptor theory
-
STEPHENSON, R. P. (1956). A modification of receptor theory. Br. J. Pharmacol. 11, 379-393.
-
(1956)
Br. J. Pharmacol.
, vol.11
, pp. 379-393
-
-
Stephenson, R.P.1
-
41
-
-
0017652208
-
A model of two functionally antagonistic receptor populations achieved by the same agonist
-
SZABADI, E. (1977). A model of two functionally antagonistic receptor populations achieved by the same agonist. J. theor. Biol. 69, 101-112.
-
(1977)
J. Theor. Biol.
, vol.69
, pp. 101-112
-
-
Szabadi, E.1
-
42
-
-
0002163185
-
Molecular basis of pharmacologic selectivity
-
Pratt W. B. & Taylor P., eds. New York: Churchill Livingstone
-
TAYLOR, P. & INSEL, P. A. (1990). Molecular basis of pharmacologic selectivity. In: Principles of Drug Actions - The Basis of Pharmacology, Third edition (Pratt W. B. & Taylor P., eds) pp. 1-102. New York: Churchill Livingstone.
-
(1990)
Principles of Drug Actions - The Basis of Pharmacology, Third Edition
, pp. 1-102
-
-
Taylor, P.1
Insel, P.A.2
-
43
-
-
0015535998
-
On the analysis of pharmacological experiments in term of an allosteric receptor model
-
THRON, C. D. (1973). On the analysis of pharmacological experiments in term of an allosteric receptor model. Mol. Pharmacol. 9, 1-9.
-
(1973)
Mol. Pharmacol.
, vol.9
, pp. 1-9
-
-
Thron, C.D.1
-
44
-
-
84965047860
-
Pharmacodynamics of drugs affecting skeletal muscle. Structure-action relationships in homologous series of quaternary ammonium salts
-
VAN ROSSUM, J. M. & ARIËNS, E. J. (1959a). Pharmacodynamics of drugs affecting skeletal muscle. Structure-action relationships in homologous series of quaternary ammonium salts. Arch. Int. Pharmacodynamie Therapie 118, 393-417.
-
(1959)
Arch. Int. Pharmacodynamie Therapie
, vol.118
, pp. 393-417
-
-
Van Rossum, J.M.1
Ariëns, E.J.2
-
45
-
-
84965076157
-
Pharmacodynamics of parasympathetic drugs. Structure-action relationships in homologous series of quaternary ammonium salts
-
VAN ROSSUM, J. M. & ARIËNS, E. J. (1959b). Pharmacodynamics of parasympathetic drugs. Structure-action relationships in homologous series of quaternary ammonium salts. Arch. Int. Pharmacodynamie Therapie 118, 418-446.
-
(1959)
Arch. Int. Pharmacodynamie Therapie
, vol.118
, pp. 418-446
-
-
Van Rossum, J.M.1
Ariëns, E.J.2
-
46
-
-
0027300816
-
The competitive and noncompetitive antagonism of receptor-mediated drug actions in the presence of spare receptors
-
ZHU, B. T. (1993). The competitive and noncompetitive antagonism of receptor-mediated drug actions in the presence of spare receptors. J. Pharmacol. Toxicol. Methods 29, 85-91.
-
(1993)
J. Pharmacol. Toxicol. Methods
, vol.29
, pp. 85-91
-
-
Zhu, B.T.1
|