Simultaneous radiometric and fluorimetric detection of lauric acid metabolites using high-performance liquid chromatography following esterification with 4-bromomethyl-6,7-dimethoxycoumarin in human and rat liver microsomes

Journal of Chromatography B: Biomedical Applications

Volumn 681, Issue 2, 1996, Pages 233-239

  Amet, Y ^a   Berthou, F ^a   Menez, J F ^a  

^a FACULTÉ DE MÉDECINE ET DES SCIENCES DE LA SANTÉ   (France)

Author keywords

4 bromomethyl 6,7 dimethoxycoumarin; Hydroxylauric acid; Lauric acid

Indexed keywords

12 HYDROXYLAURIC ACID; 12-HYDROXYDODECANOIC ACID; 4 BROMOMETHYL 6,7 DIMETHOXYCOUMARIN; 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN; COUMARIN DERIVATIVE; CYTOCHROME P450 2E1; LAURIC ACID; LAURIC ACID DERIVATIVE;

ANIMAL; ARTICLE; CHEMISTRY; COMPARATIVE STUDY; ENZYMOLOGY; ESTERIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIVER MICROSOME; MALE; METABOLISM; METHODOLOGY; RADIOMETRY; RAT; REPRODUCIBILITY; SPECTROFLUOROMETRY; SPRAGUE DAWLEY RAT;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARINS; CYTOCHROME P-450 CYP2E1; ESTERIFICATION; HUMANS; LAURIC ACIDS; MALE; MICROSOMES, LIVER; RADIOMETRY; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, FLUORESCENCE;

EID: 0030573409     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-4347(96)00043-6     Document Type: Article

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