The chemical evolution of N,N-dimethyl-2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethylamine (L-741,604) and analogues: Potent and selective agonists for 5-HT(1D) receptors

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 15, 1996, Pages 1825-1830

  Sternfeld, Francine ^a   Baker, Raymond ^a   Broughton, Howard B ^a   Guiblin, Alexander R ^a   Jelley, Richard A ^a   Matassa, Victor G ^a   Reeve, Austin J ^a   Beer, Margaret S ^a   Stanton, Josephine A ^a   Hargreaves, Richard J ^a   Shepheard, Sara L ^a   Longmore, Jeanette ^a   Razzaque, Zerin ^a   Graham, Michael I ^a   Sohal, Bindi ^a   Street, Leslie J ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; 3 [2 (DIMETHYLAMINO)ETHYL] 5 (1,2,4 TRIAZOL 1 YL)INDOLE; INDOLE DERIVATIVE; N [4 [5 [3 (2 AMINOETHYL) 1H INDOL 5 YL] 1,2,4 OXADIAZOL 3 YL]BENZYL]METHANESULFONAMIDE; N,N DIMETHYL 2 [5 (1,2,4 TRIAZOL 4 YL) 1H INDOL 3 YL]ETHYLAMINE; RECEPTOR SUBTYPE; RIZATRIPTAN; SEROTONIN 1D RECEPTOR; SUMATRIPTAN; SUMATRIPTAN SUCCINATE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; BRAIN; BRAIN REGION; CONTROLLED STUDY; DOG; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; INTRAVENOUS DRUG ADMINISTRATION; MIGRAINE; RAT; STRUCTURE ACTIVITY RELATION; SWINE;

ANIMALIA; CANIS FAMILIARIS; SUS SCROFA;

EID: 0030572495     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00324-1     Document Type: Article

References (21)

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