Modelisation, synthesis and antiviral evaluation of new 2,3-disubstituted thiazolidinone nucleoside analogues

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 15, 1996, Pages 1775-1780

  Graciet, J C ^a,b   Niddam, V ^a,b   Gamberoni, M ^a,b   Trabaud, C ^a,b   Dessolin, J ^a,b   Medou, M ^a,b   Mourier, N ^a,b   Zoulim, F ^b   Borel, C ^b   Hantz, O ^b   Camplo, M ^a,b   Chermann, J C ^b   Kraus, J L ^a,b  

^a AIX MARSEILLE UNIVERSITY   (France)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 THIAZOLIDINONE DERIVATIVE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIVIRUS AGENT; LAMIVUDINE; NUCLEOSIDE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; CALCULATION; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG DESIGN; DRUG SYNTHESIS; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

HEPATITIS B VIRUS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030572475     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00316-2     Document Type: Article

References (22)

1. 1-Pepe, G.; Meyer, M.; Faury, P.; Graciet, J.C.; Chermann, J.C. and Kraus, J.L. Eur. J. Med. Chem. 1996. Accepted for publication.
2. 2-Schaeffer, H.J.; Beauchamp, I.; de Miranda, P.; Elion, G.B.; Bauer, D.J.; Collins, P. Nature 1978, 272, 583-585.
3. 3-a) Watanabe, K.A.; Reichman, U.; Hirota, K.; Lopez, C.; Fox, J.J. J. Med. Chem. 1979, 22, 21-24.
4. b) Zoulim, F.; Dannaoui, E.; Borel, C.; Hantz, O.; Lin, T.S.; Liu, S.H.; Trepo, C.; Cheng, Y. C. Antimicrob. Agents Chemother. 1996, 40, 448-453.
5. 4-Vince, R.; Hua, M.; Brownell, J.; Daluge, S.; Lee, F.; Shannon, W.M.; Lavelle, G.C.; Qualls, J.; Weislow, O.S.; Kiser, R.; Canonico, P.G.; Schultz, R.H.; Narayanan, V.L.; Mayo, J.G.; Shoemaker, R.H.; Boyd, M.R Biochem. Biophys. Res. Commun. 1988, 156, 1046-1053.
6. 5-Hoshino, H.; Shimizu, N. J. Antibiot. 1987, 40, 1077-1078.
7. th Internat. Conferences on AIDS Montreal (Quebec) June 4-6th 1989 (45-76), N.T.C.O.
8. 7-Belleau, B.; NGuyen-Ba, N.; Kraus, J.L.; Greenberg, M.S.; Wainberg, M.A.; Wilkes, B.C.; Schiller, P.W.; Dionne, G. Trends in Receptor Research, Angeli, P.; Gulini, U.; Quaglia, W. Editors, 1992, Elsevier Science, 7-30.
9. 8-Van Roey P.; Taylor E.W.; Chu C. K. and Schinazi R. F. Ann. N. Y. Acad. Sci. 1991, 29-30.
10. 9-Pepe, G. and Siri, D. J. Mol. Graphics 1990, 7, 93-101.
11. 10-Cavalier-Frontin, F.; Pepe, G.; Verducci, J.; Siri, D.; Jacquier, R. J. Am. Chem. Soc. 1992, 114, 8885-8890.
12. 11-Graciet, J.C.; Faury, P.; Camplo, M.; Charvet, A.S.; Mourier, N.; Trabaud, C.; Niddam, V.; Simon, V. and Kraus, J.L. Nucleosides and Nucleotides 1995, 14, 1379-1392.
13. 12-Nishimoto S.I.; Hatta H.; Ueshima H. and Kagiya T. J. Med. Chem. 1992, 35, 2711-2712.
14. 13-Harada, S.; Koyanagi, Y.; Yamamoto, N. Science 1985, 229, 563-566.
15. 14-Rey, F.; Barre-Sinoussi, F.; Schmidtmayerova, H. and Chermann, J. C. J. Virol. Methods. 1987, 16, 239-249.
16. 15-Rey, F.; Donker, G.; Hirsch, I. and Chermann J.C. Virology 1991, 181, 165-171.
17. 16-Guillouzou, A.; Guguen-Guillouzou, C. Methods for preparation of adult and fetal hepatocytes. In "Isolated and cultured hepatocytes," Guillouzou, A. and Guguen-Guillouzou, Editors 1986, 1-12, les éditions INSERM.
18. 17-Fourel, I.; Giripon, P.; Hantz, O.; Cova, L.; Lambert, V.; Jacquet, C.; Watanabe, K.; Fox, J.; Guillouzou, C.; Trepo, C. Hepatology 1989, 10, 186-191.
19. 18-Fourel I.; Li J.; Hantz O.; Jacquet C.; Fox J. and Trepo C. J. Med. Virol. 1992, 37, 122-126.
20. 19-Graciet, J.C. PhD Thesis 1996, Université de la Méditerranée, Marseille, France.
21. 20-Gao, W., Cara, A., Gallo, R. and Lori, F. Proc. Natl. Acad. Sci. USA 1993, 90, 8925-8928.
22. 21-Aggarwal, S.; Gogu, S.; Rangan, S. and Agrawal, K. J. Med. Chem. 1990, 33, 1505-1510.