Ring opening and ring closure reactions of 1,2,4-triazines with carbon nucleophiles: A novel route to functionalized 3-aminopyridazines

Tetrahedron Letters

Volumn 37, Issue 32, 1996, Pages 5795-5796

  Rykowski, Andrzej ^a   Woliñska, Ewa ^a  

^a SIEDLCE UNIVERSITY OF NATURAL SCIENCES AND HUMANITIES   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 TRIAZINE DERIVATIVE; PYRIDAZINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0030570867     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01228-2     Document Type: Article

References (8)

1. 1. Part 4 in 1,2,4-triazines in organic synthesis. For part 3, see Rykowski A.; Lipińska T. Synth. Commun. submitted.
2. 2. Boger D.L. ; Weinreb S.N. in "Hetero Diels-Alder Methodology in Organic Synthesis"; Academic Press: New York, 1987; pp. 323-335.
3. 3. Charushin V.N.; Alexeevev S.G.; Chupakhin O.N.; van der Plas H.C. Adv. Heterocycl. Chem. 1989, 46, 73-155.
4. 4. Rykowski A.; van der Plas H.C. J. Org. Chem. 1987, 52, 71-73.
5. 5. Rykowski A.; van der Plas H.C. J. Heterocycl. Chem. 1982, 19, 653-656.
6. 6. Ellis G.P. in "Synthesis of fused heterocycles"; John Wiley and Sons Inc: New York, 1987; pp. 226-239.
7. +) 272. 1062, found 272. 1061.
8. 3, 200 MHz) δ 2.42 (s,3 H), 2.61 (s, 3H), 4.03 (d, 1H, J=9 Hz), 4.09 (d, 1H, J=6 Hz), 5.27 (d, 1H, J=9 Hz), 5.48 (d, 1H, J=6 Hz), 7.18-7.77 (m, 20 H), 7.82 (s, 1H, NH), 8.45 (s, 1H, NH).