A new indole synthesis via [3 + 3] annulation of 2-(benzotriazol-1-ylmethyl)pyrroles with α,β-unsaturated aldehydes and ketones

Tetrahedron Letters

Volumn 37, Issue 32, 1996, Pages 5641-5644

  Katritzky, Alan R ^a   Levell, Julian R ^a   Li, Jianqing ^a  

^a University of Florida ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INDOLE DERIVATIVE; PYRROLE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0030570861     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)01216-6     Document Type: Article

References (18)

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15. 13); followed by a further portion of 1-propargylbenzotriazole (0.16 mol, 32%). Overall recrystallised yield = 72%.
16. 12. Katritzky, A. R.; Li, J.; Malhotra, N. Liebigs Ann. Chem. 1992, 843.
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18. 14. 90% of the theoretical volume of n-butyllithium in hexanes was added, after which the solution was titrated dropwise up to the point at which one more drop of n-butyllithium turned the solution a deep indigo-blue colour, and this colour did not dissipate to give a deep brown / yellow solution.