Peripheral electrophysiological responses decrease in response to repetitive painful stimulation of the human nasal mucosa

Neuroscience Letters

Volumn 212, Issue 1, 1996, Pages 37-40

  Hummel, T ^a   Schiessl, C ^a   Wendler, J ^a   Kobal, G ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Electrophysiology; Irritation; Nociception; Pain; Periphery

Indexed keywords

ADULT; ARTICLE; ELECTROPHYSIOLOGY; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NERVE FIBER C; NOCICEPTIVE RECEPTOR; NOCICEPTIVE STIMULATION; NORMAL HUMAN; NOSE MUCOSA; PAIN; PAIN ASSESSMENT; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; STIMULUS RESPONSE;

EID: 0030570388     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12767-1     Document Type: Article

References (21)

1. [1] Adriaensen, H., Gybels, J., Handwerker, H.-O. and Van Hees, J., Response properties of thin myelinated (A-delta) fibers in human skin nerves, J. Neurophysiol., 49 (1983) 111-122.
2. [2] Anton, F. and Peppel, P., Central projections of trigeminal primary afferents innervating the nasal mucosa: a horseradish peroxidase study in the rat, Neuroscience, 41 (1991) 617-628.
3. [3] Arendt-Nielsen, L., Petersen-Felix, S., Fischer, M., Bak, P., Bjerring, P. and Zbinden, A.M., The effect of N-methyl-D-aspartate antagonist (ketamine) on single and repeated nociceptive stimuli: a placebo-controlled experimental human study, Anesth. Analg., 81 (1995) 63-68.
4. [4] Handwerker, H.-O., Anton, F. and Reeh, P.W., Discharge patterns of afferent cutaneous nerve fibers from the rat's tail during prolonged noxious mechanical stimulation, Exp. Brain Res., 65 (1987) 493-504.
5. [5] Handwerker, H.-O., Iggo, A. and Zimmermann, M., Segmental and supraspinal actions on dorsal horn neurons responding to noxious and non-noxious skin stimuli, Pain, 1 (1975) 147-165.
6. [6] Hummel, T., Gruber, M., Pauli, E. and Kobal, G., Event-related potentials in response to repetitive painful stimulation, Electroenceph. clin. Neurophysiol., 92 (1994) 426-432.
7. [7] Hummel, T., Knecht, M. and Kobal, G., Peripherally obtained electrophysiological responses to olfactory stimulation in man: electro-olfactograms exhibit a smaller degree of desensitization compared with subjective intensity estimates, Brain Res. (1996) in press.
8. [8] Hummel, T., Lötsch, J., Kraetsch, H.G. and Kobal, G. Anti-nociceptive and anti-inflammatory effects of ibuprofen, Naunyn-Schmiedeberg's Arch. Pharmacol., 349 (1994) R138.
9. [9] Kobal, G., Elektrophysiologische Untersuchungen des menschlichen Geruchssinnes, Georg Thieme Verlag, Stuttgart, 1981.
10. [10] Kobal, G., Pain-related electrical potentials of the human respiratory nasal mucosa elicited by chemical stimulation, Pain, 22 (1985) 151-163.
11. [11] Kobal, G., Van Toller, S. and Hummel, T., Is there directional smelling? Experientia, 45 (1989) 130-132.
12. [12] Lang, J., Clinical Anatomy of the Nose, Nasal Cavity and Paranasal Sinuses, Georg Thieme Verlag, Stuttgart, 1989, pp. 112-116.
13. [13] Mackenzie, R.A., Burke, D., Skuse, N.F. and Lethlean, A.K., Fiber function and perception during cutaneous nerve block, J. Neurol. Neurosurg. Psychiatry, 38 (1975) 865-873.
14. [14] Ottoson, D., Analysis of the electrical activity of the olfactory epithelium, Acta Physiol. Scand., 35 (1956) 1-83.
15. [15] Price, D.D., Characteristics of second pain and flexion reflexes indicative of prolonged central summation, Exp. Neurol., 37 (1972) 371-387.
16. [16] Sekizawa, S.I. and Tsubone, H., Nasal receptors responding to noxious chemical irritants, Respir. Physiol., 96 (1994) 37-48.
17. [17] Sumino, R. and Dubner, R., Response characteristics of specific thermoreceptive afferents innervating monkey facial skin and their relationship to human thermal sensitivity, Brain Res. Rev., 3 (1981) 105-122.
18. [18] Thürauf, N., Friedel, I., Hummel, C. and Kobal, G., The mucosal potential elicited by noxious chemical stimuli: is it a peripheral nociceptive event, Neurosci. Lett., 128 (1991) 297-300.
19. [19] Thürauf, N., Hummel, T., Kettenmann, B. and Kobal, G., Nociceptive and reflexive responses recorded from the human nasal mucosa, Brain Res., 629 (1993) 293-299.
20. [20] Torebjörk, H.E. and Hallin, R.G., C-fibre units recorded from human sensory nerve fascicles in situ, Acta Soc. Med. Ups., 75 (1975) 81-84.
21. [21] Torebjörk, H.E. and Hallin, R.G., Perceptual changes accompanying controlled preferential blocking of A and C fibre responses in intact human skin nerves. Exp. Brain Res., 16 (1971) 321-332.