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Volumn 50, Issue 3, 1996, Pages 273-279

Deregulated expression of cloned transcription factor E2F-1 in Chinese hamster ovary cells shifts protein patterns and activates growth in protein-free medium

Author keywords

CHO cell; E2F 1; Metabolic engineering; Serum free cell culture; Two dimensional electrophoresis of proteins

Indexed keywords

ANIMAL CELL CULTURE; CELLS; ELECTROPHORESIS; GENES; GROWTH KINETICS; MICROSCOPIC EXAMINATION; PROTEINS;

EID: 0030570134     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19960505)50:3<273::AID-BIT6>3.0.CO;2-D     Document Type: Article
Times cited : (40)

References (30)
  • 2
    • 0027985749 scopus 로고
    • E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vitro
    • Beijersbergen, R. L., Kerkhoven, R. M., Zhu, L. A., Carlee, L., Voorhoeve, P. M., Bernards, R. 1994. E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vitro. Genes Devel. 8: 2680-2690.
    • (1994) Genes Devel. , vol.8 , pp. 2680-2690
    • Beijersbergen, R.L.1    Kerkhoven, R.M.2    Zhu, L.A.3    Carlee, L.4    Voorhoeve, P.M.5    Bernards, R.6
  • 3
    • 0029041375 scopus 로고
    • Mapping the cell's nucleus
    • Baskin, Y. 1995. Mapping the cell's nucleus. Science 268: 1564-1565.
    • (1995) Science , vol.268 , pp. 1564-1565
    • Baskin, Y.1
  • 4
    • 0028361374 scopus 로고
    • Regulation of two E2F-related genes in presenescent and senescent human fibroblasts
    • Dimri, G. P., Hara, E., Campisi, J. 1994. Regulation of two E2F-related genes in presenescent and senescent human fibroblasts. J. Biol. Chem. 269: 16180-16186.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16180-16186
    • Dimri, G.P.1    Hara, E.2    Campisi, J.3
  • 5
    • 0027936238 scopus 로고
    • Phosphorylation of E2F-1 modulates its interaction with the retinoblastoma gene product and the adenoviral E4 19 kDa protein
    • Fagan, R., Flint, K. J., Jones, N. 1994. Phosphorylation of E2F-1 modulates its interaction with the retinoblastoma gene product and the adenoviral E4 19 kDa protein. Cell 78: 799-811.
    • (1994) Cell , vol.78 , pp. 799-811
    • Fagan, R.1    Flint, K.J.2    Jones, N.3
  • 8
    • 0027497372 scopus 로고
    • The retinoblastoma protein as a transcription repressor
    • Helin, K., Harlow, E. 1993. The retinoblastoma protein as a transcription repressor. Trends Cell. Biol. 3: 43-46.
    • (1993) Trends Cell. Biol. , vol.3 , pp. 43-46
    • Helin, K.1    Harlow, E.2
  • 9
    • 0026652346 scopus 로고
    • A cDNA encoding a pRb-binding protein with properties of the transcription factor E2F
    • Helin, K., Lees, J. A., Vidal, M., Dyson, N., Harlow, E., Fattaey, A. 1992. A cDNA encoding a pRb-binding protein with properties of the transcription factor E2F. Cell 70: 337-350.
    • (1992) Cell , vol.70 , pp. 337-350
    • Helin, K.1    Lees, J.A.2    Vidal, M.3    Dyson, N.4    Harlow, E.5    Fattaey, A.6
  • 11
    • 0027367144 scopus 로고
    • Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F
    • Ivey-Hoyle, M., Conroy, R., Huber, H. E., Goodhart, P. J., Oliff, A., Heimbrook, D. C. 1993 Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F. Mol. Cell Biol. 13: 7802-7812.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 7802-7812
    • Ivey-Hoyle, M.1    Conroy, R.2    Huber, H.E.3    Goodhart, P.J.4    Oliff, A.5    Heimbrook, D.C.6
  • 12
    • 0027491775 scopus 로고
    • Expression of transcription factor E2F1 induces quiescent cells to enter S phase
    • Johnson, D. G., Schwartz, J. K., Cress, W. D., Nevins, J. R. 1993. Expression of transcription factor E2F1 induces quiescent cells to enter S phase. Nature 365: 349-352.
    • (1993) Nature , vol.365 , pp. 349-352
    • Johnson, D.G.1    Schwartz, J.K.2    Cress, W.D.3    Nevins, J.R.4
  • 13
    • 0028362359 scopus 로고
    • Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
    • Krek, W., Ewen, M. E., Shirodkar, S., Arany, Z., Kaelin, W. G., Livingston, D. M. 1994. Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell 78: 161-172.
    • (1994) Cell , vol.78 , pp. 161-172
    • Krek, W.1    Ewen, M.E.2    Shirodkar, S.3    Arany, Z.4    Kaelin, W.G.5    Livingston, D.M.6
  • 14
    • 0027769885 scopus 로고
    • Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members
    • Krek, W., Livingston, D. M., Shirodkar, S. 1993. Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members. Science 262: 1557-1560.
    • (1993) Science , vol.262 , pp. 1557-1560
    • Krek, W.1    Livingston, D.M.2    Shirodkar, S.3
  • 15
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 16
    • 0028267869 scopus 로고
    • DRTF1/E2F: An expanding family of heterodimeric transcription factors implicated in cell-cycle control
    • LaThangue, N. B. 1994. DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control. TIBS 19: 108-114.
    • (1994) TIBS , vol.19 , pp. 108-114
    • LaThangue, N.B.1
  • 18
    • 0030570124 scopus 로고    scopus 로고
    • Two dimensional electrophoresis of proteins as a tool in the metabolic engineering of cell cycle regulation
    • this issue
    • Lee, K. H., Harrington, M. G., Bailey, J. E Two dimensional electrophoresis of proteins as a tool in the metabolic engineering of cell cycle regulation. Biotechnol. Bioeng. (this issue).
    • Biotechnol. Bioeng.
    • Lee, K.H.1    Harrington, M.G.2    Bailey, J.E.3
  • 20
    • 0028216582 scopus 로고
    • Altered shape and cell-cycle characteristics of fibroblasts expressing the E2F-1 transcription factor
    • Logan, T. J., Jordan, K. L., Hall, D. 1994. Altered shape and cell-cycle characteristics of fibroblasts expressing the E2F-1 transcription factor. Mol. Biol. Cell 5: 667-678.
    • (1994) Mol. Biol. Cell , vol.5 , pp. 667-678
    • Logan, T.J.1    Jordan, K.L.2    Hall, D.3
  • 21
    • 0028136903 scopus 로고
    • Transcription of the E2F-1 gene is rendered cell-cycle dependent by E2F DNA-binding sites within its promoter
    • Neuman, E., Flemington, E. K., Sellers, W. R., Kaelin, W. G. 1994. Transcription of the E2F-1 gene is rendered cell-cycle dependent by E2F DNA-binding sites within its promoter. Mol. Cell Biol. 14: 6607-6615.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 6607-6615
    • Neuman, E.1    Flemington, E.K.2    Sellers, W.R.3    Kaelin, W.G.4
  • 22
    • 0026526437 scopus 로고
    • E2F: A link between the Rb tumor suppressor protein and viral oncoproteins
    • Nevins, J. R. 1992. E2F: a link between the Rb tumor suppressor protein and viral oncoproteins. Science 258: 424-429.
    • (1992) Science , vol.258 , pp. 424-429
    • Nevins, J.R.1
  • 24
    • 0028801689 scopus 로고
    • Phosphorylation of a specific CDK site in E2F-1 affects its electrophoretic mobility and promotes pRb-binding in vitro
    • Pepper, D. S., Keblusek, P., Helin, K., Toebes, M., Vandereb, A. J., Zantema, A. 1995. Phosphorylation of a specific CDK site in E2F-1 affects its electrophoretic mobility and promotes pRb-binding in vitro. Oncogene 10: 39-48.
    • (1995) Oncogene , vol.10 , pp. 39-48
    • Pepper, D.S.1    Keblusek, P.2    Helin, K.3    Toebes, M.4    Vandereb, A.J.5    Zantema, A.6
  • 25
    • 84873782420 scopus 로고
    • Genetics of somatic mammalian cells. III. Long-term cultivation of euploid cells from human and animal subjects
    • Puck, T. T., Cieciura, S. J., Robinson, A. 1958. Genetics of somatic mammalian cells. III. Long-term cultivation of euploid cells from human and animal subjects. J. Exp. Med. 108: 945-955.
    • (1958) J. Exp. Med. , vol.108 , pp. 945-955
    • Puck, T.T.1    Cieciura, S.J.2    Robinson, A.3
  • 26
    • 0029347496 scopus 로고
    • Recombinant cyclin e expression activates proliferation and obviates surface attachment of Chinese hamster ovary (CHO) cells in protein-free medium
    • Renner, W., Lee, K. H., Hatzimanikatis, V., Bailey, J. E., Eppenberger, H. 1995. Recombinant cyclin E expression activates proliferation and obviates surface attachment of Chinese hamster ovary (CHO) cells in protein-free medium. Biotechnol. Bioeng. 47: 476-482.
    • (1995) Biotechnol. Bioeng. , vol.47 , pp. 476-482
    • Renner, W.1    Lee, K.H.2    Hatzimanikatis, V.3    Bailey, J.E.4    Eppenberger, H.5
  • 27
    • 0028360766 scopus 로고
    • Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation
    • Singh, P., Wong, S. H., Hong, W. 1994. Overexpression of E2F-1 in rat embryo fibroblasts leads to neoplastic transformation. EMBO J. 13: 3329-3338.
    • (1994) EMBO J. , vol.13 , pp. 3329-3338
    • Singh, P.1    Wong, S.H.2    Hong, W.3
  • 28
    • 0017527790 scopus 로고
    • Cell cycle of Saccharomyces cerevisiae in populations growing at different rates
    • Slater, M. L., Sharrow, S. O., Gart, J. J. 1977. Cell cycle of Saccharomyces cerevisiae in populations growing at different rates. Proc. Natl. Acad. Sci. USA 74: 3850-3854.
    • (1977) Proc. Natl. Acad. Sci. USA , vol.74 , pp. 3850-3854
    • Slater, M.L.1    Sharrow, S.O.2    Gart, J.J.3
  • 29
    • 0028961625 scopus 로고
    • Production of recombinant proteins in Chinese hamster ovary cells using a protein-free cell culture medium
    • Zang, M., Trautmann, H., Gandor, C., Messi, F., Asselbergs, F., Leist, C., Fiechter, A., Reiser, J. 1995. Production of recombinant proteins in Chinese hamster ovary cells using a protein-free cell culture medium. Bio/Technology 13: 389-392.
    • (1995) Bio/Technology , vol.13 , pp. 389-392
    • Zang, M.1    Trautmann, H.2    Gandor, C.3    Messi, F.4    Asselbergs, F.5    Leist, C.6    Fiechter, A.7    Reiser, J.8
  • 30
    • 0029134617 scopus 로고
    • Sequential activation of cydin E and cyclin A gene expression by human papillomavirus type-16 E7 through sequences necessary for transformation
    • Zerfass, K., Schulze, A., Spitkovsky, D., Friedman, V., Henglein, B., Jansendurr, P. 1995. Sequential activation of cydin E and cyclin A gene expression by human papillomavirus type-16 E7 through sequences necessary for transformation. J. Virol. 69: 6389-6399.
    • (1995) J. Virol. , vol.69 , pp. 6389-6399
    • Zerfass, K.1    Schulze, A.2    Spitkovsky, D.3    Friedman, V.4    Henglein, B.5    Jansendurr, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.