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Volumn 49, Issue 3, 1996, Pages 247-258

Optimization of nonlinear biotechnological processes with linear programming: Application to citric acid production by Aspergillus niger

Author keywords

Aspergillus niger; carbohydrate metabolism; citric acid; linear programming

Indexed keywords

BIOSYNTHESIS; CARBOHYDRATES; ENZYMES; FUNGI; LINEAR PROGRAMMING; MATHEMATICAL MODELS; METABOLISM; METABOLITES; ORGANIC ACIDS; PHYSIOLOGY;

EID: 0030569904     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19960205)49:3<247::AID-BIT2>3.0.CO;2-K     Document Type: Article
Times cited : (65)

References (27)
  • 1
    • 0024792701 scopus 로고
    • Evolutionary quantitative genetics: How little do we know?
    • Barton, N. H., Turelli, M. 1989. Evolutionary quantitative genetics: How little do we know? Ann. Rev. Genet. 23: 337-370.
    • (1989) Ann. Rev. Genet. , vol.23 , pp. 337-370
    • Barton, N.H.1    Turelli, M.2
  • 3
    • 0015989446 scopus 로고
    • A linear steady state treatment of enzymatic chains. General properties. Control and effector streght
    • Heinrich, R., Rappoport, T. A. 1974. A linear steady state treatment of enzymatic chains. General properties. Control and effector streght. Eur. J. Biochem. 42: 89-95.
    • (1974) Eur. J. Biochem. , vol.42 , pp. 89-95
    • Heinrich, R.1    Rappoport, T.A.2
  • 7
    • 0026453975 scopus 로고
    • The production of organic acids
    • Mattey, M. 1992. The production of organic acids. CRC Crit. Rev. Biotechnol. 12: 87-132.
    • (1992) CRC Crit. Rev. Biotechnol. , vol.12 , pp. 87-132
    • Mattey, M.1
  • 8
    • 0026782902 scopus 로고
    • A strategy for increasing an in vivo flux by genetic manipulations. The tryptophan system of yeast
    • Niederberger, P., Prasad, R , Miozzari, G., Kacser, H. 1992. A strategy for increasing an in vivo flux by genetic manipulations. The tryptophan system of yeast Biochem. J 287: 473-479.
    • (1992) Biochem. J , vol.287 , pp. 473-479
    • Niederberger, P.1    Prasad, R.2    Miozzari, G.3    Kacser, H.4
  • 9
    • 0026504156 scopus 로고
    • Evolutionary optimization of the catalytic efficiency of enzymes
    • Pettersson, G. 1992. Evolutionary optimization of the catalytic efficiency of enzymes. Eur. J. Biochem. 206: 289-295.
    • (1992) Eur. J. Biochem. , vol.206 , pp. 289-295
    • Pettersson, G.1
  • 10
    • 0027174006 scopus 로고
    • Optimal kinetic design of enzymes in a linear metabolic pathway
    • Pettersson, G. 1993. Optimal kinetic design of enzymes in a linear metabolic pathway. Biochem. Biophys. Acta 1164, 1-7.
    • (1993) Biochem. Biophys. Acta , vol.1164 , pp. 1-7
    • Pettersson, G.1
  • 11
    • 0014649230 scopus 로고
    • Biochemical systems analysis. I. Some mathematical properties of the rate law for the component enzymatic reactions
    • Savageau, M. A. 1969. Biochemical systems analysis. I. Some mathematical properties of the rate law for the component enzymatic reactions. J. Theor. Biol 25: 365-369.
    • (1969) J. Theor. Biol , vol.25 , pp. 365-369
    • Savageau, M.A.1
  • 12
    • 0014658880 scopus 로고
    • Biochemical systems analysis. II. The steadystate solutions for an n-pool system using a power-law approximation
    • Savageau, M. A. 1969. Biochemical systems analysis. II. The steadystate solutions for an n-pool system using a power-law approximation. J. Theor. Biol. 25: 370-379.
    • (1969) J. Theor. Biol. , vol.25 , pp. 370-379
    • Savageau, M.A.1
  • 13
    • 0015231849 scopus 로고
    • Parameter sensitivity as a criterion for evaluating and comparing the performance of biochemical systems
    • Savageau, M. A. 1971. Parameter sensitivity as a criterion for evaluating and comparing the performance of biochemical systems. Nature 229: 542-544.
    • (1971) Nature , vol.229 , pp. 542-544
    • Savageau, M.A.1
  • 14
    • 0015103748 scopus 로고
    • Concepts relating behaviour systems to their underlying molecular properties
    • Savageau, M. A. 1971. Concepts relating behaviour systems to their underlying molecular properties. Arch. Biochem. Biophys. 145: 612-621.
    • (1971) Arch. Biochem. Biophys. , vol.145 , pp. 612-621
    • Savageau, M.A.1
  • 15
    • 0342349799 scopus 로고
    • Recasting nonlinear differential equations as S-systems. A canonical nonlinear form
    • Savageau, M. A., Voit, E O. 1987. Recasting nonlinear differential equations as S-systems. A canonical nonlinear form. Math. Biosci. 87: 83-115.
    • (1987) Math. Biosci. , vol.87 , pp. 83-115
    • Savageau, M.A.1    Voit, E.O.2
  • 16
    • 0007941325 scopus 로고
    • Increased citric acid production by mutants of Aspergillus niger with increased glycolytic capacity
    • Schreferl-Kunar, G., Grotz. M., Rohr, M., Kubicek, C. P. 1989. Increased citric acid production by mutants of Aspergillus niger with increased glycolytic capacity. FBMS Microbiol. Lett. 59: 297-300.
    • (1989) FBMS Microbiol. Lett. , vol.59 , pp. 297-300
    • Schreferl-Kunar, G.1    Grotz, M.2    Rohr, M.3    Kubicek, C.P.4
  • 17
    • 0001112639 scopus 로고
    • Minimization of intermediate concentrations as a suggested optimality principle for biochemical networks I Theoretical analysis
    • Schuster, S., Heinrich, R. 1991, Minimization of intermediate concentrations as a suggested optimality principle for biochemical networks I Theoretical analysis. J. Math. Biol. 29: 425-442
    • (1991) J. Math. Biol. , vol.29 , pp. 425-442
    • Schuster, S.1    Heinrich, R.2
  • 18
    • 0025935927 scopus 로고
    • Minimization of intermediate concentrations as a suggested optimality principle for biochemical networks. II. Time hierarchy, enzymatic rate laws, and erythrocyte metabolism
    • Schuster, S., Schuster, R., Heinrich, R. 1991. Minimization of intermediate concentrations as a suggested optimality principle for biochemical networks. II. Time hierarchy, enzymatic rate laws, and erythrocyte metabolism. J. Math. Biol. 29: 443-455.
    • (1991) J. Math. Biol. , vol.29 , pp. 443-455
    • Schuster, S.1    Schuster, R.2    Heinrich, R.3
  • 20
    • 13344269350 scopus 로고
    • A comparison of variant theories of intact biochemical systems 1. Enzyme-enzyme interactions and biochemical systems theory
    • Sorribas, A., Savageau, M. A. 1989. A comparison of variant theories of intact biochemical systems 1. Enzyme-enzyme interactions and biochemical systems theory. Math. Biosci. 86: 127-145.
    • (1989) Math. Biosci. , vol.86 , pp. 127-145
    • Sorribas, A.1    Savageau, M.A.2
  • 21
    • 0028765255 scopus 로고
    • Modeling approach to control of carbohydrate metabolism during citric acid accumulation by Aspergillus niger. I Model definition and stability of the steady state
    • Torres, N. V. 1994. Modeling approach to control of carbohydrate metabolism during citric acid accumulation by Aspergillus niger. I Model definition and stability of the steady state. Biotechnol. Bioeng 44: 104-111.
    • (1994) Biotechnol. Bioeng , vol.44 , pp. 104-111
    • Torres, N.V.1
  • 22
    • 0028765252 scopus 로고
    • Modeling approach to control of carbohydrate metabolism during citric acid accumulation by Aspergillus niger. II. Steady state analysis and optimization
    • Torres, N. V. 1994. Modeling approach to control of carbohydrate metabolism during citric acid accumulation by Aspergillus niger. II. Steady state analysis and optimization. Biotechnol. Bioeng. 44: 112-118.
    • (1994) Biotechnol. Bioeng. , vol.44 , pp. 112-118
    • Torres, N.V.1
  • 23
    • 0023661067 scopus 로고
    • Accuracy of alternative representations for integrated biochemical systems
    • Voit, E. O., Savageau, M A 1987. Accuracy of alternative representations for integrated biochemical systems. Biochemistry 26: 6869-6880.
    • (1987) Biochemistry , vol.26 , pp. 6869-6880
    • Voit, E.O.1    Savageau, M.A.2
  • 25
    • 0026911028 scopus 로고
    • Optimization of integrated biochemical systems
    • Voit, E. O. 1992. Optimization of integrated biochemical systems. Biotechnol. Bioeng. 40. 572-582.
    • (1992) Biotechnol. Bioeng. , vol.40 , pp. 572-582
    • Voit, E.O.1
  • 26
    • 0028003497 scopus 로고
    • An evolutionary approach to enzyme kinetics: Optimization of ordered mechanisms
    • Wilhelm, T., Hoffmann-Klipp, E., Heinrich, R. 1994. An evolutionary approach to enzyme kinetics: optimization of ordered mechanisms. Bull Math Biol 56, 65-106
    • (1994) Bull Math Biol , vol.56 , pp. 65-106
    • Wilhelm, T.1    Hoffmann-Klipp, E.2    Heinrich, R.3
  • 27
    • 0026463865 scopus 로고
    • The tricarboxylic acid cycle in Dictyostelium discoideum. IV Resolution of discrepancies between alternative methods of analysis
    • Shiraishi, F., Savageau, M A. 1992. The tricarboxylic acid cycle in Dictyostelium discoideum. IV Resolution of discrepancies between alternative methods of analysis. J. Biol Chem. 267: 22934-22943.
    • (1992) J. Biol Chem. , vol.267 , pp. 22934-22943
    • Shiraishi, F.1    Savageau, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.