Glycation mediated crosslinking between α-crystallin and MP26 in intact lens membranes

Mechanisms of Ageing and Development

Volumn 91, Issue 1, 1996, Pages 65-78

  Prabhakaram, Malladi ^a   Katz, Martin L ^a   Ortwerth, Beryl J ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

Cataract; Glycation; L threose; Lens; Membranes; MP26; crystallin

Indexed keywords

ALPHA CRYSTALLIN; ASCORBIC ACID; LENS PROTEIN; MEMBRANE PROTEIN 26; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS LINKING; GLYCATION; LENS EPITHELIUM; LENS FIBER; MOLECULAR WEIGHT; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SENILE CATARACT;

ANIMALIA; BOVINAE;

EID: 0030568968     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/0047-6374(96)01781-2     Document Type: Article

References (30)

1. [1] E.R. Berman, In E.R. Herman (ed.), Biochemistry of the Eye, Plenum Press, New York, 1991, pp. 201-290.
2. [2] A. Pirie, Color and solubility of the proteins of human cataracts. Invest. Ophthalmol., 7 (1968) 634-650.
3. [3] J. Bours, Isotachophoresis and immunoelectrophoresis of water soluble and insoluble crystallins of the ageing bovine lens. Curr. Eye Res., 3 (1984) 691-697.
4. [4] M. Takehana and L. Takemoto, Quantitation of membrane-associated crystallins" from aging and cataractous human lenses. Invest, Ophthalmol. Vis, Sci., 28 (1987) 780-784.
5. [5] G. Chandrasekhar and R.J. Cenedella, Protein associated with human lens 'native' membrane during aging and cataract formation. Exp. Eye Res., 60 (1995) 707-717.
6. [6] J.W.M. Mulders, J. Stokkermans, J.A.M. Leunissen, E. Benedetti, H. Blomendal and W.W. DeJong, Interaction of α-crystallin with lens plasma membranes. Affinity for MP26. Eur. J. Biochem., 152 (1985) 721-728.
7. [7] F. Ifeanyi and L. Takemoto, Interaction of lens crystallins with lipid vesicles. Exp. Eye Res., 53 (1991) 535-538.
8. [8] C.R. Fleschner and R.J. Cenedella, Examination of a lens native plasma membrane fraction and its associated crystallins. Curr. Eye Res., 11 (1992) 739-752.
9. [9] B.J. Ortwerth, J.A. Speaker, M. Lopez, E. Li and M.S. Feather, Ascorbic acid glycation; the reaction of L-threose in lens tissue. Exp. Eye Res., 58 (1994) 665-674.
10. [10] M. Prabhakaram and B.J. Ortwerth, Glycation of MP26 and MP 22 in bovine lens membranes. Biochem. Biophys. Res. Commn., 185 (1992a) 496-504.
11. [11] L.J. Takemoto, J.S. Hansen and J. Horwitz, Inter species conservation of the main intrinsic polypeptide (MIP) of the lens membrane. Comp. Biochem. Physiol, 68B (1981) 101-106.
12. [12] V.M. Monnier, In J.E. Baynes and V.M. Monnier (eds), The Maillard Reaction in Aging, Diabetes and Nutrition, Alan R. Liss, New York, 1989, pp. 1-22.
13. [13] R.E. Perry, M.S. Swamy and E.C. Abraham, Progressive changes in lens crystallin glycation and high molecular weight aggregate formation leading to cataract development in streptozotocin-diabetic rats. Exp. Eye Res., 44 (1987) 269-282.
14. [14] B.J. Ortwerth, P.R. Olesen, K.K. Sharma and M. Prabhakaram, Chemical modification of alpha crystallin. Exp. Eye Res., 56 (1993) 107-114.
15. [15] M. Prabhakaram and B.J. Ortwerth, The glycation and cross-linking of isolated lens crystallins by ascorbic acid. Exp. Eye Res., 55 (1992b) 451-459.
16. [16] P. Russell, W.G. Robison and J.H. Kinoshita, A new method for rapid isolation of the intrinsic membrane proteins from lens. Exp. Eye Res., 32 (1981) 511-516.
17. [17] U.K. Laemmli, Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 277 (1970) 680-685.
18. [18] H. Towbin, T. Staehelin and J. Gordon, Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose: procedure and some applications. Proc. Natl. Acad. Sci. USA, 76 (1979) 4350-4354.
19. [19] M.L. Katz, C. Gao and H.J. Stientjes, Regulation of the inter photoreceptor retinoid-binding protein content of the retina by vitamin A. Exp. Eye Res., 57 (1993) 393-401.
20. 131I-labeled human growth hormone of high specific radioactivity. Biochem. J., 89 (1963) 114-123.
21. [21] L. J. Takemoto, J.S. Hansen and J. Horwitz, High molecular weight aggregates from human cataracts: characterization by Western Blot analysis. Biochem. Biophys. Res. Commn., 122 (1984) 1028-1033.
22. [22] B.J. Ortwerth, M. Linetsky and P.R. Olesen, Ascorbic acid glycation of lens proteins produces UVA sensitizers similar to those in human lens. Photochem. Photobiol., 62 (1995) 454-462.
23. [23] M.G. Lopez and M.S. Feather, The production of threose as a degradation product from L-ascorbic acid. J. Carbohydr. Chem., 11 (1992) 799-800.
24. [24] M.B. Gorin, S.B. Yancey, J. Cline, J.P. Revel and J. Horwitz, The major intrinsic protein (MIP) of the bovine lens fiber membrane. Characterization and structure based on cDNA cloning. Cell, 39 (1984) 49-59.
25. [25] B.J. Ortwerth, S.H. Slight, M. Prabhakaram, Y. Sun and J.B. Smith, Site specific glycation of lens crystallins by ascorbic acid. Biochim. Biophys. Acta, 1117 (1992) 207-215.
26. [26] E.G. Abraham, M. Cherian and J.B. Smith, Site-specificity in the glycation of α A and α B crystallins by glucose. Biochem. Biophys. Res. Commn., 201 (1994) 1451-1456.
27. [27] R.J. Cenedella and G. Chandrasekhar, High capacity binding of alpha crystallins to various bovine lens membrane preparations. Curr. Eye Res., 12 (1993) 1025-1038.
28. [28] W. Lohmann, W. Schmehl and J. Strobel, Nuclear cataract. Oxidative damage to the lens. Exp. Eye Res., 43 (1986) 859-862.
29. [29] S. Som, D. Mukherjee, S. Deb, R. Choudhury, S.N. Mukherjee, S.N. Chatterjee and I.B. Chatterjee, Ascorbic acid metabolism in diabetes mellitus. Metabolism, 30 (1981) 572-577.
30. [30] M. Prabhakaram and B.J. Ortwerth, The glycation-associated crosslinking of lens proteins by ascorbic acid is not mediated by oxygen free radicals. Exp. Eye Res., 53 (1991) 261-168.