Protein-ligand interactions. 6 Nicotinic acetylcholine receptor agonist activity of isoquinoline alkaloids

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 23, 1996, Pages 2801-2806

  Whiteley, C G ^a   Daya, S ^a  

^a RHODES UNIVERSITY   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; BERBERINE; ISOQUINOLINE; ISOQUINOLINE ALKALOID; NICOTINIC RECEPTOR; PAPAVERINE; TUBOCURARINE CHLORIDE;

ARTICLE; BINDING AFFINITY; BINDING SITE; DRUG RECEPTOR BINDING; FLUOROMETRY; IN VITRO STUDY; LIGAND BINDING; NONHUMAN; SPECTROPHOTOMETRY; TORPEDO;

TORPEDO FUSCOMACULATA;

EID: 0030568129     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(96)00429-5     Document Type: Article

References (15)

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9. max is the change in fluorescence at full saturation with ligand.
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12. C) were calculated from the intercept on the abscissa. The logarithmic relationship of equation 5 is analogous to the Hill equation and a slope (p) that differs from unity should reflect either heterogeneity in binding sites or co-operativity in binding.
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