The subtype-selective α2-adrenoceptor antagonists BRL 44408 and ARC 239 also recognize 5-HT(1A) receptors in the rat brain

European Journal of Pharmacology

Volumn 312, Issue 3, 1996, Pages 385-388

  Meana, J Javier ^a   Callado, Luis F ^a   Pazos, Angel ^b   Grijalba, Bernardo ^b   García Sevilla, Jesús A ^c  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b UNIVERSITY OF CANTABRIA   (Spain)

^c UNIVERSITAT DE LES ILLES BALEARS   (Spain)

Author keywords

5 HT(1A) receptor; ARC 239; Brain; BRL 44408; Rat; 2 Adrenoceptor subtype

Indexed keywords

2 (1 METHYL 2 ISOINDOLINYLMETHYL) 2 IMIDAZOLINE; 2 (2 METHOXY 1,4 BENZODIOXAN 2 YL) 2 IMIDAZOLINE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 2 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 4,4 DIMETHYL 1,3(2H,4H) ISOQUINOLINEDIONE; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; PHENTOLAMINE; RECEPTOR SUBTYPE; SEROTONIN 1A RECEPTOR;

ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN CORTEX; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

EID: 0030567956     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(96)00598-5     Document Type: Article

References (17)

1. 2-adrenergic receptors, FASEB J. 6, 832.
2. Bylund, D.B., C. Ray-Prenger and T.J. Murphy, 1988, Alpha-2A and alpha-2B adrenergic receptor subtypes: antagonist binding in tissues and cell lines containing only one subtype, J. Pharmacol. Exp. Ther. 245, 600.
3. 1A receptors in human cerebral cortex, Eur. J. Pharmacol. 159, 307.
4. 3H]RX821002 binding and definition of additional selective drugs, Eur. J. Pharmacol. 252, 43.
5. 2B-adrenoceptor subtypes in postmortem human brain, J. Neurochem. 58, 1555.
6. 2-adrenoceptor subtypes, Naunyn-Schmiedeberg's Arch. Pharmacol. 353, 391.
7. 1A recognition sites, Brain Res. 376, 85.
8. 2-adrenergic receptor, Science 238, 650.
9. Alpha-2A adrenergic receptors in the control of nociception, motor behavior and hippocampal synthesis of noradrenaline, J. Pharmacol. Exp. Ther. 270, 958.
10. Alpha2A adrenergic receptor and other populations of alpha-2 adrenergic subtypes, J. Pharmacol. Exp. Ther. 270, 946.
11. 2A subtype, J. Neurochem. 63, 1077.
12. 1D receptors, Eur. J. Pharmacol. 196, 213.
13. 2D-subtype?, Eur. J. Pharmacol. 219, 203.
14. 2A-selective compound, Eur. J. Pharmacol. 202, 235.
15. 3H]Idazoxan, Neurochem. Int. 17, 537.
16. Winter, J.C. and R.A. Rabin, 1992, Yohimbine as a serotonergic agent: evidence from receptor binding and drug discrimination, J. Pharmacol. Exp. Ther. 263, 682.
17. 2B-adrenoceptor subtypes, Eur. J. Pharmacol. 168, 381.