A versatile mechanism based reaction probe for the direct selection of biocatalysts

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 17, 1996, Pages 2117-2120

  Lo, Lee Chiang ^a   Lo, Chih Hung L ^a   Janda, Kim D ^a   Kassel, Daniel B ^b   Raushel, Frank M ^c  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Formerly CombiChem Inc   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MANDELIC ACID DERIVATIVE;

ARTICLE; CATALYSIS; DRUG MANUFACTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; PROTEIN MODIFICATION; REACTION ANALYSIS;

EID: 0030567863     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00379-4     Document Type: Article

References (13)

1. Kirby, A. L. Angew. Chem. Int. Ed. Engl. 1996, 35, 707.
2. Bartel, D. P.; Szostak J. W. Science 1993, 267, 1411.
3. Janda, K. D.; Chen, Y.-C. J. In The Pharmacology of Monoclonal Antibodies, Rosenberg M.; Moore G. P., Eds.; Springer-Verlag; Berlin, 1994, p 209.
4. Burton, D. R.; Barbas III, C. F. Advanced In IImmunology 1994, 57, 191
5. Janda, K. D.; Lo, C.-H. L.; Li, T.; Barbas III, C. F.; Wirsching, P.; Lerner, R. A. Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 2532.
6. Soumillion, P.; Jespers L.; Bouchet, M.; Marchand-Brynaert, J.; Winter G.; Fastrez, J. J. Mol. Biol. 1994, 237, 415.
7. + 669.1353, found 669.1359.
8. Wakselman M. Nouv. J. Chim. 1983, 7, 439.
9. Myers, J. K.; Widlanski, T. S Science 1993, 262, 1451.
10. Dumas, D. P.; Caldwell, S. R.; Wild, J. R.; Raushel F. M. J. Biol. Chem. 1989, 264, 19659.
11. Omburo, G. A.; Kuo, J. M.; Mullins, L. S; Raushel, F. M.J. Biol. Chem. 1992, 267, 13278.
12. 19F NMR spectra.
13. Banzon J. A.; Kuo J. M.; Miles B. W.; Fischer D. R.; Stang P. J.; Raushel F. M. Biochemistry 1995, 34, 743.