UV-induced mutations of supF gene on a shuttle vector plasmid in p53-deficient mouse cells are qualitatively different from those in wild-type cells

Mutation Research - DNA Repair

Volumn 364, Issue 1, 1996, Pages 43-49

  Ishizaki, Kanji ^a   Nishizawa, Kimiko ^a   Mimaki, Sachiyo ^a   Aizawa, Shin Ichi ^b  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Mutagenesis; p53; Shuttle vector plasmid; Ultraviolet

Indexed keywords

PROTEIN P53;

ANIMAL CELL; ARTICLE; DNA REPAIR; EMBRYO; FIBROBLAST; MOUSE; MUTATION; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SHUTTLE VECTOR; ULTRAVIOLET RADIATION;

ANIMALIA;

EID: 0030565496     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/0921-8777(96)00020-1     Document Type: Article

References (24)

1. Akasaka, S., Takimoto, K. and Yamamoto, K. (1992) G:C → T:A and G:C → C:G transversions are the predominant spontaneous mutations in the Escherichia coli supF gene: an improved lacZ(am) E. coli host designed for assaying pZ189 supF mutational specificity, Mol. Gen. Genet., 235, 173-178.
2. Bakalkin, G., Yakovleva, T., Selivanova, G., Magnusson, K.P., Szekely, L., Kiseleva, E., Klein, G., Terenius, L. and Wiman, K.G. (1994) p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer. Proc. Natl. Acad. Sci. USA, 91, 413-417.
3. Basic-Zaninovic, T., Meschini, R., Calcagnile, A.S., Palombo, F., D'Errico, M., Proietti-De Sanctis, L. and Dogliotti, E. (1995) Strand bias of ultraviolet light-induced mutations in a transcriptionally active gene in human cells, Mol. Carcinogenesis, 14, 214-225.
4. Donehower, L.A., Harvey, M., Slagle, B.L., McArthur, M.J., Montgomery Jr. C.A., Butel, J.S. and Bradley, A. (1992) Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors, Nature, 356, 215-221.
5. Dutta, A., Ruppert, J.M., Aster, J.C. and Winchester, E. (1993) Inhibition of DNA replication factor RPA by p53, Nature, 365, 79-82.
6. Ford, J.M. and Hanawalt, P.C. (1995) Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair hut exhibit normal transcription-coupled repair et al.coupled repair and enhanced UV-resistance, Proc. Natl. Acad. Sci. USA. 92, 8876-8880.
7. Gozukara, E.M., Parris, C.N., Weber, C.A., Salazar, E.P., Seidman, M.M., Watkins, J.F., Prakash, L.P. and Kraemer, K.H. (1994) The human DNA repair gene. ERCC2(XPD), corrects ultraviolet hypersensitivity and ultraviolet hypermutability of a shuttle vector replicated in xeroderma pigmentosum group D cells, Cancer Res., 54, 3837-3844.
8. Greenblatt, M.S., Bennett, W.P., Hollstein, M. and Harris, C.C. (1994) Mutations in the p53 tumor suppresser genes: Clues to cancer etiology and molecular pathogenesis, Cancer Res., 54, 4855-4878.
9. Hartwell, L. (1992) Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells, Cell, 71, 543-546.
10. Hutchinson, F. (1994) Induction of tandem-base change mutations. Mutation Res., 309, 11-15.
11. Ishizaki, K., Ejima, Y., Matsunaga, T., Hara, R., Sakamoto, A., Ikenaga, M., Ikawa, Y. and Aizawa, S. (1994) Increased UV-induced SCEs but normal repair of DNA damage in p53-deficient mouse cells, Int. J. Cancer, 58, 254-257.
12. Lane, D.P. (1992) p53. guardian of the genome, Nature, 358, 15-16.
13. Lee, J.M., Abrahamson, J.L.A., Kandel, R., Donehower, L.A. and Bernstein, A. (1994) Susceptibility to radiation-carcinogenesis and accumulation of chromosomal breakage in p53 deficient mice, Oncogene, 9, 3731-3736.
14. Lee, S., Elenbaas, B., Levine, A. and Griffith, J. (1995) p53 and its 14-kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches, Cell, 81, 1013-1020.
15. 1 arrest in two closely related human lymphoblast cell lines that differ in p53 status, J. Biol. Chem., 270, 11033-11036.
16. Livingstone, L.R., White, A., Sprouse, J., Livanos, E., Jacks, T. and Tisty, T.D. (1992) Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53, Cell, 70, 923-935.
17. 6-methyl-guanine-DNA methyltransferase-deficient cells in comparison with proficient cells, Cancer Res., 51, 6219-6223.
18. Nishino, H., Knoll, A., Buettner, V.L., Frisk, C.S., Maruta, Y., Haavik, J. and Sommer, S.S. (1995) p53 wild-type and p53 nullizygous Big Blue transgenic mice have similar frequencies and patterns of observed mutations in liver, spleen and brain, Oncogene, 11, 263-270.
19. Sands, A.T., Suraokar, M.B., Sanchez, A., Marth, J.E., Donehower, L.A. and Bradley, A. (1995) p53 deficiency dose not affect the accumulation of point mutations in a transgene target, Proc. Natl. Acad. Sci. USA, 92, 8517-8521.
20. Thomas D.C. and Kunkel, T.A. (1993) Replication of UV-irradiated DNA in human cell extracts: Evidence for mutagenic bypass of pyrimidine dimers, Proc. Natl. Acad. Sci. USA, 90, 7744-7748.
21. Tsukada, T., Tomooka, Y., Takai, S., Ueda, Y., Nishikawa, S., Yagi, T., Tokunaga, T., Takeda, N., Suda, Y., Abe, S., Matsuo, I., Ikawa, Y. and Aizawa, S. (1993) Enhanced proliferative potential in culture of cells from p53-deficient mice, Oncogene, 8, 3313-3322.
22. Williams, B.O., Remington L., Albert, D.M., Mukai, S., Bronson, R.T. and Jacks, T. (1994) Cooperative tumorigenic effects of germline mutations in Rb and p53, Nature Genet., 7, 480-484.
23. Yagi, T., Sato, M., Nishigori, C. and Takebe, H. (1994) Similarity in the molecular profile of mutations induced by UV light in shuttle vector plasmids propagated in mouse and human cells, Mutagenesis, 9, 73-77.
24. Yin, Y., Tainsky, M.A., Bischoff, F.Z., Strong, L.C. and Wahl, G.M. (1992) Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles, Cell, 70, 937-948.