The altered activity of membrane-bound protein kinase C in human liver cancer

Cancer Letters

Volumn 105, Issue 2, 1996, Pages 211-215

  Chang, King Jen ^a   Lin, Jen Kun ^a   Lee, Po Huang ^a   Hsieh, Yih Shou ^b   Cheng, Chih Kai ^b   Liu, Jer Yuh ^b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Liver cancer; Protein kinase C

Indexed keywords

MEMBRANE ENZYME; PROTEIN KINASE C;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; LIVER CANCER; PRIORITY JOURNAL;

EID: 0030565021     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3835(96)04283-8     Document Type: Article

References (22)

1. [1] Nishizuka, Y. (1984) The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature, 308, 693-698.
2. [2] Sharkey, N.A., Leach, K.L. and Blumberg, P.M. (1984) Competitive inhibition by diacylglycerol of specific phorbol ester binding. Proc. Natl. Acad. Sci. USA, 81, 607-610.
3. [3] Niedel, J.E., Kuhn, L.J. and Vandenbark, G.R. (1983) Phorbol diester receptor copurifies with protein kinase C. Proc. Natl. Acad. Sci. USA, 80, 36-40.
4. [4] Berridge, M.J. (1987) Inositol triphosphate and diacylglycerol: two interacting second messengers. Annu. Rev, Biochem., 56, 159-193.
5. [5] Rozengurt, E. (1989) Signal transduction pathways in mitogenesis. Br. Med. Bull., 45, 515-528.
6. [6] Nishizuka, Y. ( 1988) The molecular heterogeneity of protein kinase C and its implication for cellular regulation. Nature, 334, 661-665.
7. [7] Reifenberger, G., Deckert, M. and Wechsler, W. (1989) Immunohistochemical determination of protein kinase C expression and proliferative activity in human brain tumors. Acta Neuropathol., 78, 166-175.
8. [8] O'Brian, C.A., Vogel, V.G., Singletary, S.E. and Ward, N.E. (1989) Elevated protein kinase expression in human breast tumor biopsies relative to normal breast tissue. Cancer Res., 49, 3215-3217.
9. [9] Alvaro, V., Touratine, P.H., Vozari, R.R., Bai-Grenier, F., Birman, P. and Joubert, D. (1992) Protein kinase C activity and expression in normal and adenomatous human pituitaries. Int. J. Cancer, 50, 724-730.
10. [10] Coudwell, W.T., Antel, J.P. and Yong, V.W. (1992) Protein kinase C activity correlates with the growth rate of malignant gliomas. II. Effects of glioma mitogens and modulators of protein kinase C. Neurosurgery, 31, 717-724.
11. [11] Kopp, R., Noelke, B., Sauter, G., Schileberg, F.W., Paumgartner, G. and Pfeiffer, A. (1991) Altered protein kinase C activity in human colonic adenoma and carcinomas. Cancer Res., 51, 205-210.
12. [12] Kusunoki, M., Sakanoue, Y., Hatada, T., Yanagi, F., Tamamura, T. and Utsunomiya, J. (1992) Protein kinase C activity in human colonic adenoma and colorectal carcinoma. Cancer, 69, 24-30.
13. [13] Horn, F., Marks, F., Fisher, G., Marcelo, C.L. and Voorhees, J.J. (1987) Decreased protein kinase C activity in psoriatic versus normal epidermis. J. Invest. Dermatol., 88, 220-222.
14. [14] Vivier, J. and Schabort, J.C. (1985) Aflatoxin B1 alters protein phosphorylation in rat livers. Biochem. Biophys. Res. Commun., 129, 342-349.
15. [15] Weber, A., Cottreau, D., Henry, J., Phan Kinh Tuy, F., Shala, H. and Kahn, A. (1983) Protein kinase of rat liver during hepatocarcinogenesis induced by an azo dye. Eur. J. Biochem., 130, 447-456.
16. [16] Liu, J.Y., Lin, S.J. and Lin, J.K. (1993) Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoyl-phorbol-13-acetate (TPA) in NIH3T3 cells. Carcinogenesis, 14, 857-861.
17. [17] Kikkawa, U., Takai, Y., Minakuchi, R., Inohara, S. and Nishizuka, Y. (1982) Calcium-activated, phospholipid-dependent protein kinase from rat brain: subcellular distribution, purification and properties. J. Biol. Chem., 257, 13341-13348.
18. [18] Barbacid, M. (1987) Ras genes. Annu. Rev. Biochem., 56, 779-827.
19. [19] Devivo, I., Marion, M.J., Smith, S.J., Carney, W.P. and Brandt-Rauf, P.W. (1994) Mutant c-Ki-ras p21 protein in chemical carcinogenesis in humans exposed to vinyl chloride. Cancer Causes Control, 5, 273-278.
20. [20] Ogata, N., Kamimura, T. and Asakura, H. (1991) Point mutation, allelic loss and increased methylation of c-Ha-ras gene in human hepatocellular carcinoma. Hepatology, 13, 31-37.
21. [21] Shiota, G., Kawasaki, H., Nakamura, T. and Schmidt, E.V. (1994) Inhibitory effect of hepatocyte growth factor against FaO hepatocellular carcinoma cells may be associated with changes of intracellular signalling pathways mediated by protein kinase C. Res. Commun. Mol. Pathol. Pharmacol., 85, 271-279.
22. [22] Shiota, G., Rhoads, D.B., Wang, T.C., Nakamura, T. and Schmidt, E.V. (1992) Hepatocyte growth factor inhibits growth of hepatocellular carcinoma cells. Proc. Natl. Acad. Sci. USA, 89, 373-377.