메뉴 건너뛰기




Volumn 124, Issue 2, 1996, Pages 157-169

Enhanced capacity of n-3 fatty acid-enriched macrophages to oxidize low density lipoprotein mechanisms and effects of antioxidant vitamins

Author keywords

Atherosclerosis; Fish oil; Lipid peroxidation; Low density lipoprotein oxidation; Macrophages

Indexed keywords

5,8,11,14 ICOSATETRAYNOIC ACID; ALPHA TOCOPHEROL; ANTIOXIDANT; FISH OIL; LOW DENSITY LIPOPROTEIN; OMEGA 3 FATTY ACID; UNCLASSIFIED DRUG;

EID: 0030565020     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/0021-9150(96)05818-2     Document Type: Article
Times cited : (24)

References (51)
  • 1
    • 0024603895 scopus 로고
    • Beyond cholesterol: Modification of low-density lipoprotein that increase its atherogenicity
    • [1] Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol: modification of low-density lipoprotein that increase its atherogenicity. N Engl J Med 1989;320:915.
    • (1989) N Engl J Med , vol.320 , pp. 915
    • Steinberg, D.1    Parthasarathy, S.2    Carew, T.E.3    Khoo, J.C.4    Witztum, J.L.5
  • 2
    • 0026333959 scopus 로고
    • Role of oxidized low density lipoprotein in atherogenesis
    • [2] Witztum JL, Steinberg D. Role of oxidized low density lipoprotein in atherogenesis. J Clin Invest 1991;88:1785.
    • (1991) J Clin Invest , vol.88 , pp. 1785
    • Witztum, J.L.1    Steinberg, D.2
  • 4
    • 0026874975 scopus 로고
    • Workshop participants, antioxidants in the prevention of human atherosclerosis. Summary of the proceedings of a National Heart, Lung and Blood Institute Workshop: September 5-6, 1991, Bethesda, Maryland
    • [4] Steinberg D. Workshop Participants, Antioxidants in the prevention of human atherosclerosis. Summary of the proceedings of a National Heart, Lung and Blood Institute Workshop: September 5-6, 1991, Bethesda, Maryland. Circulation 1992;85:2338.
    • (1992) Circulation , vol.85 , pp. 2338
    • Steinberg, D.1
  • 5
    • 0011172276 scopus 로고
    • A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein
    • [5] Parthasarathy S, Wieland E, Steinberg D. A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein. Proc Natl Acad Sci USA 1989;86:1046.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1046
    • Parthasarathy, S.1    Wieland, E.2    Steinberg, D.3
  • 6
    • 0022538758 scopus 로고
    • Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells
    • [6] Heinecke JW, Baker L, Rosen H, Chait A. Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells. J Clin Invest 1986;77:757.
    • (1986) J Clin Invest , vol.77 , pp. 757
    • Heinecke, J.W.1    Baker, L.2    Rosen, H.3    Chait, A.4
  • 7
    • 0025756633 scopus 로고
    • Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages
    • [7] Rankin SM, Parthasarathy S, Steinberg D. Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages. J Lipid Res 1991;32:449.
    • (1991) J Lipid Res , vol.32 , pp. 449
    • Rankin, S.M.1    Parthasarathy, S.2    Steinberg, D.3
  • 8
    • 0027421804 scopus 로고
    • Mechanisms of copper- and iron-dependent oxidative modification of human low density lipoprotein
    • [8] Lynch SM, Frei B. Mechanisms of copper- and iron-dependent oxidative modification of human low density lipoprotein. J Lipid Res 1993;34:1745.
    • (1993) J Lipid Res , vol.34 , pp. 1745
    • Lynch, S.M.1    Frei, B.2
  • 11
    • 0026511875 scopus 로고
    • Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man
    • [11] Regnstrom J, Nilsson J, Tornvall P, Landou C, Hamsten A. Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man. Lancet 1992;339:1183.
    • (1992) Lancet , vol.339 , pp. 1183
    • Regnstrom, J.1    Nilsson, J.2    Tornvall, P.3    Landou, C.4    Hamsten, A.5
  • 12
    • 0026562523 scopus 로고
    • Effects of d-α-tocopherol supplementation on experimentally induced primate atherosclerosis
    • [12] Verlangieri AJ, Bush MJ. Effects of d-α-tocopherol supplementation on experimentally induced primate atherosclerosis. J Am Coll Nutr 1992;11:131.
    • (1992) J Am Coll Nutr , vol.11 , pp. 131
    • Verlangieri, A.J.1    Bush, M.J.2
  • 13
    • 0023392413 scopus 로고
    • Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia
    • [13] Kita T, Nagano Y, Yokode M, Ishii K, Kume N, Ooshima A. Yoshida H, Kawai C. Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia. Proc Natl Acad Sci USA 1987;84:5928.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 5928
    • Kita, T.1    Nagano, Y.2    Yokode, M.3    Ishii, K.4    Kume, N.5    Ooshima, A.6    Yoshida, H.7    Kawai, C.8
  • 16
    • 0028089663 scopus 로고
    • Effects of supplementing with vitamin E on the uptake of low density lipoprotein and the stimulation of cholesteryl ester formation in macrophages
    • [16] Suzukawa M, Abbey M, Clifton P, Nestel PJ. Effects of supplementing with vitamin E on the uptake of low density lipoprotein and the stimulation of cholesteryl ester formation in macrophages. Atherosclerosis 1994;110:77.
    • (1994) Atherosclerosis , vol.110 , pp. 77
    • Suzukawa, M.1    Abbey, M.2    Clifton, P.3    Nestel, P.J.4
  • 17
    • 0026770939 scopus 로고
    • Evidence for an additional intracellular site of action of probucol in the prevention of oxidative modification of low density lipoprotein. Use of a new water-soluble probucol derivative
    • [17] Parthasarathy S. Evidence for an additional intracellular site of action of probucol in the prevention of oxidative modification of low density lipoprotein. Use of a new water-soluble probucol derivative. J Clin Invest 1992;89:1618.
    • (1992) J Clin Invest , vol.89 , pp. 1618
    • Parthasarathy, S.1
  • 18
    • 0028196610 scopus 로고
    • Macrophage-mediated oxidation of extracellular low density lipoprotein requires an initial binding of the lipoprotein to its receptor
    • [18] Aviram M, Rosenblat M, Macrophage-mediated oxidation of extracellular low density lipoprotein requires an initial binding of the lipoprotein to its receptor. J Lipid Res 1994;35:385.
    • (1994) J Lipid Res , vol.35 , pp. 385
    • Aviram, M.1    Rosenblat, M.2
  • 19
    • 0025708317 scopus 로고
    • The oxidative modification of low-density lipoproteins by macrophages
    • [19] Leake DS, Rankin SM. The oxidative modification of low-density lipoproteins by macrophages. Biochem J 1990;270:741.
    • (1990) Biochem J , vol.270 , pp. 741
    • Leake, D.S.1    Rankin, S.M.2
  • 20
    • 84950170953 scopus 로고
    • Effects of fish oil fatty acids on low density lipoprotein size, oxidizability and uptake by macrophages
    • [20] Suzukawa M, Abbey M, Howe PRC, Nestel PJ. Effects of fish oil fatty acids on low density lipoprotein size, oxidizability and uptake by macrophages. J Lipid Res 1995;36:473.
    • (1995) J Lipid Res , vol.36 , pp. 473
    • Suzukawa, M.1    Abbey, M.2    Howe, P.R.C.3    Nestel, P.J.4
  • 22
    • 0018668515 scopus 로고
    • Rate of exchange of esterified cholesterol between human plasma and high density lipoproteins
    • [22] Barter PJ, Jones ME. Rate of exchange of esterified cholesterol between human plasma and high density lipoproteins. Atherosclerosis 1979;34:67.
    • (1979) Atherosclerosis , vol.34 , pp. 67
    • Barter, P.J.1    Jones, M.E.2
  • 23
    • 0023697101 scopus 로고
    • Development of an automated Lowry protein assay for the Cobas-Bio centrifugal analyzer
    • [23] Clifton PM, Chang L, Mackinnon AM. Development of an automated Lowry protein assay for the Cobas-Bio centrifugal analyzer. Anal Biochem 1988;172:165.
    • (1988) Anal Biochem , vol.172 , pp. 165
    • Clifton, P.M.1    Chang, L.2    Mackinnon, A.M.3
  • 24
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • [24] Buege JA, Aust SD. Microsomal lipid peroxidation. Methods Enzymol 1978;52:302.
    • (1978) Methods Enzymol , vol.52 , pp. 302
    • Buege, J.A.1    Aust, S.D.2
  • 25
    • 0025189674 scopus 로고
    • Effect of fish oil on lipoproteins, lecithin: Cholesterol acyltransferase, and lipid transfer protein activity in humans
    • [25] Abbey M, Clifton P, Kestin M, Belling B, Nestel P. Effect of fish oil on lipoproteins, lecithin:cholesterol acyltransferase, and lipid transfer protein activity in humans. Arteriosclerosis 1990;10:85.
    • (1990) Arteriosclerosis , vol.10 , pp. 85
    • Abbey, M.1    Clifton, P.2    Kestin, M.3    Belling, B.4    Nestel, P.5
  • 26
    • 0026515759 scopus 로고
    • Cellular oxidative modification of low density lipoprotein dose not require lipoxygenases
    • [26] Sparrow CP, Olszewski J. Cellular oxidative modification of low density lipoprotein dose not require lipoxygenases. Proc Natl Acad Sci USA 1992;89:128.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 128
    • Sparrow, C.P.1    Olszewski, J.2
  • 27
    • 0027464243 scopus 로고
    • Assessment of 5-lipoxygenase involvement in human monocyte-mediated LDL oxidation
    • [27] Folcik VA, Cathcart MK. Assessment of 5-lipoxygenase involvement in human monocyte-mediated LDL oxidation. J Lipid Res 1993;34:69.
    • (1993) J Lipid Res , vol.34 , pp. 69
    • Folcik, V.A.1    Cathcart, M.K.2
  • 28
    • 0026545259 scopus 로고
    • Effect of dietary monounsaturated and polyunsaturated fatty acids on the susceptibility of plasma low density lipoprotein to oxidative modification
    • [28] Bonanome A, Pagnon A, Biffanti S, Opportune A, Sorgato F, Dorella M, Maiorino M, Ursini F. Effect of dietary monounsaturated and polyunsaturated fatty acids on the susceptibility of plasma low density lipoprotein to oxidative modification. Arterioscler Thromb 1992;12:529.
    • (1992) Arterioscler Thromb , vol.12 , pp. 529
    • Bonanome, A.1    Pagnon, A.2    Biffanti, S.3    Opportune, A.4    Sorgato, F.5    Dorella, M.6    Maiorino, M.7    Ursini, F.8
  • 29
    • 0027411170 scopus 로고
    • Oxidation of low-density lipoproteins: Intraindividual variability and the effect of dietary linoleate supplementation
    • [29] Abbey M, Belling GB, Noakes M, Hirata F, Nestel PJ. Oxidation of low-density lipoproteins: intraindividual variability and the effect of dietary linoleate supplementation. Am J Clin Nutr 1993;57:391.
    • (1993) Am J Clin Nutr , vol.57 , pp. 391
    • Abbey, M.1    Belling, G.B.2    Noakes, M.3    Hirata, F.4    Nestel, P.J.5
  • 30
    • 0027402693 scopus 로고
    • Effects of oleate-rich and linoleaterich diets on the susceptibility of low density lipoprotein to oxidative modification in mildly hypercholesterolemic subjects
    • [30] Reaven PD, Parthasarathy S, Grasse BJ, Miller E, Steinberg D, Witztum J. Effects of oleate-rich and linoleaterich diets on the susceptibility of low density lipoprotein to oxidative modification in mildly hypercholesterolemic subjects. J Clin Invest 1993;91:668.
    • (1993) J Clin Invest , vol.91 , pp. 668
    • Reaven, P.D.1    Parthasarathy, S.2    Grasse, B.J.3    Miller, E.4    Steinberg, D.5    Witztum, J.6
  • 33
    • 0022411156 scopus 로고
    • Long-term effects of dietary marine ω-3 fatty acids upon plasma and cellular lipids, platelet function, and eicosanoid formation in humans
    • [33] von Schacky C, Fischer S, Weber PC. Long-term effects of dietary marine ω-3 fatty acids upon plasma and cellular lipids, platelet function, and eicosanoid formation in humans. J Clin Invest 1985;76:1626.
    • (1985) J Clin Invest , vol.76 , pp. 1626
    • Von Schacky, C.1    Fischer, S.2    Weber, P.C.3
  • 35
    • 0023928425 scopus 로고
    • Differential effects of docosahexaenoic acid and eicosapentaenoic acid on suppression of lipoxygenase pathway in peritoneal macrophages
    • [35] Lokesh BR, German B, Kinsella JE. Differential effects of docosahexaenoic acid and eicosapentaenoic acid on suppression of lipoxygenase pathway in peritoneal macrophages. Biochim Biophys Acta 1988;958:99.
    • (1988) Biochim Biophys Acta , vol.958 , pp. 99
    • Lokesh, B.R.1    German, B.2    Kinsella, J.E.3
  • 36
    • 0025966617 scopus 로고
    • Lipoxygenase mediated transformation of human low density lipoprotein to an oxidized and cytotoxic complex
    • [36] Cathcart MK, McNally AK, Chisolm GM. Lipoxygenase mediated transformation of human low density lipoprotein to an oxidized and cytotoxic complex. J Lipid Res 1991;32:63.
    • (1991) J Lipid Res , vol.32 , pp. 63
    • Cathcart, M.K.1    McNally, A.K.2    Chisolm, G.M.3
  • 37
    • 0025756633 scopus 로고
    • Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages
    • [37] Rankin SM, Parthasarathy S, Steinberg D. Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages. J Lipid Res 1991;32:449.
    • (1991) J Lipid Res , vol.32 , pp. 449
    • Rankin, S.M.1    Parthasarathy, S.2    Steinberg, D.3
  • 39
    • 0025076921 scopus 로고
    • Colocalization of 15-lipoxygenase messenger RNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions
    • [39] Yla-Hertuala S, Rosenfeld ME, Parthasarathy S, Glass, C.K., Sigal E, Witztum JL, Steinberg D. Colocalization of 15-lipoxygenase messenger RNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions. Proc Natl Acad Sci USA 1990;87:6959.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6959
    • Yla-Hertuala, S.1    Rosenfeld, M.E.2    Parthasarathy, S.3    Glass, C.K.4    Sigal, E.5    Witztum, J.L.6    Steinberg, D.7
  • 40
    • 0028076349 scopus 로고
    • Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities
    • [40] Kühn H, Belkner J, Suzuki H, Yamamoto S. Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities. J Lipid Res 1994;35:1749.
    • (1994) J Lipid Res , vol.35 , pp. 1749
    • Kühn, H.1    Belkner, J.2    Suzuki, H.3    Yamamoto, S.4
  • 41
    • 0025320409 scopus 로고
    • Dietary n-3 fatty acid supplementation reduces superoxide production and chemiluminescence in a monocyte-enriched preparation of leukocytes
    • [41] Fisher M, Levine PH, Weiner BH, Johnson MH, Doyle EM, Elis PA, Hoogasian JJ. Dietary n-3 fatty acid supplementation reduces superoxide production and chemiluminescence in a monocyte-enriched preparation of leukocytes. Am J Clin Nutr 1990;51:804.
    • (1990) Am J Clin Nutr , vol.51 , pp. 804
    • Fisher, M.1    Levine, P.H.2    Weiner, B.H.3    Johnson, M.H.4    Doyle, E.M.5    Elis, P.A.6    Hoogasian, J.J.7
  • 42
    • 0027530908 scopus 로고
    • Dose superoxide radical have a role in macrophage-mediated oxidative modification of LDL?
    • [42] Jessup W, Simpson JA, Dean RT. Dose superoxide radical have a role in macrophage-mediated oxidative modification of LDL? Atherosclerosis 1993;99:107.
    • (1993) Atherosclerosis , vol.99 , pp. 107
    • Jessup, W.1    Simpson, J.A.2    Dean, R.T.3
  • 43
    • 0026027601 scopus 로고
    • Heightened susceptibility of fish oil polyunsaturate-enriched neoplastic cells to ethane generation during lipid peroxidation
    • [43] Burns CP, Wagner BA. Heightened susceptibility of fish oil polyunsaturate-enriched neoplastic cells to ethane generation during lipid peroxidation. J Lipid Res 1991;32:79.
    • (1991) J Lipid Res , vol.32 , pp. 79
    • Burns, C.P.1    Wagner, B.A.2
  • 44
    • 0028001754 scopus 로고
    • Polyunsaturated fatty acids increase lipid radical formation induced by oxidant stress in endothelial cells
    • [44] Alexander-North L, North JA, Kiminyo KP. Buettner GR, Spector AA. Polyunsaturated fatty acids increase lipid radical formation induced by oxidant stress in endothelial cells. J Lipid Res 1994;35:1773.
    • (1994) J Lipid Res , vol.35 , pp. 1773
    • Alexander-North, L.1    North, J.A.2    Kiminyo, K.P.3    Buettner, G.R.4    Spector, A.A.5
  • 45
    • 0026520335 scopus 로고
    • Prooxidant effects of lipoxygenase-derived peroxides on the copper-initiated oxidation of low-density lipoprotein
    • [45] O'Leary VJ, Darley-Usmar VM, Russell LJ, Stone D. Prooxidant effects of lipoxygenase-derived peroxides on the copper-initiated oxidation of low-density lipoprotein. Biochem J 1992;282:631.
    • (1992) Biochem J , vol.282 , pp. 631
    • O'Leary, V.J.1    Darley-Usmar, V.M.2    Russell, L.J.3    Stone, D.4
  • 46
    • 0027196058 scopus 로고
    • A moderate in vivo vitamin E supplement counteracts the fish-oil-induced increase in in-vitro oxidation of human low-density lipoproteins
    • [46] Oostenbrug GS, Mensink RP, Hornstra G. A moderate in vivo vitamin E supplement counteracts the fish-oil-induced increase in in-vitro oxidation of human low-density lipoproteins. Am J Clin Nutr 1993;57(suppl):8275.
    • (1993) Am J Clin Nutr , vol.57 , Issue.SUPPL. , pp. 8275
    • Oostenbrug, G.S.1    Mensink, R.P.2    Hornstra, G.3
  • 47
    • 0023502602 scopus 로고
    • Tocopherol distribution and intracellular localization in human adipose tissue
    • [47] Traber MG, Kayden HJ. Tocopherol distribution and intracellular localization in human adipose tissue. Am J Clin Nutr 1987;46:488.
    • (1987) Am J Clin Nutr , vol.46 , pp. 488
    • Traber, M.G.1    Kayden, H.J.2
  • 49
    • 0001218860 scopus 로고
    • Ascorbate is an outstanding antioxidant in human blood plasma
    • [49] Frei B, England L, Ames BN. Ascorbate is an outstanding antioxidant in human blood plasma. Proc Natl Acad Sci USA 1989;86:6377.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 6377
    • Frei, B.1    England, L.2    Ames, B.N.3
  • 50
    • 0003673876 scopus 로고
    • Washington, DC: National Research Council, National Academy Press
    • [50] Food and Nutrition board. "Recommended Dietary Allowances", 10th ed. Washington, DC: National Research Council, National Academy Press, 1989.
    • (1989) "Recommended Dietary Allowances", 10th Ed.
  • 51
    • 0028693259 scopus 로고
    • Physiological requirement of vitamin E as a function of the amount and type of polyunsaturated fatty acid
    • [51] Muggli R. Physiological requirement of vitamin E as a function of the amount and type of polyunsaturated fatty acid. World Rev Nutr Diet 1994;75:166.
    • (1994) World Rev Nutr Diet , vol.75 , pp. 166
    • Muggli, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.