Chronic antipsychotic treatment alters glycine-stimulated NMDA receptor binding in rat brain

Neuroscience Letters

Volumn 213, Issue 2, 1996, Pages 137-141

  McCoy, Lance ^a   Richfield, Eric K ^a,b  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b STRONG MEMORIAL HOSPITAL   (United States)

Author keywords

Antipsychotic drug; Autoradiograph; Glycine; N Methyl D aspartate receptor; 3H MK 801

Indexed keywords

CLOZAPINE; GLYCINE RECEPTOR; HALOPERIDOL; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROLEPTIC AGENT; PIMOZIDE; RISPERIDONE; SPERMIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BRAIN REGION; CONTROLLED STUDY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

EID: 0030565008     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12834-2     Document Type: Article

References (19)

1. [1] Banerjee, S.P., Zuck, L.G., Yablonsky-Ater, E. and Lidsky, T.I., Glutamate agonist activity: implications for antipsychotic drug action and schizophrenia, NeuroReport, 6 (1995) 2500-2504.
2. [2] Baruah, S., Waziri, R. and Sherman, A., Neuroleptic effects on serine and glycine metabolism,. Biol. Psychiatry, 34 (1994) 544-550.
3. [3] Byrd, J.C., Bykov, V. and Rothman, R., Chronic haloperidol treatment up-regulates rat brain PCP receptors, Eur. J. Pharmacol., 140 (1987) 121-122.
4. [4] Fletcher, E.J. and MacDonald, J.F., Haloperidol interacts with the strychnine-insensitive glycine site at the NMDA receptor in cultured mouse hippocampal neurones, Eur. J. Pharmacol., 235 (1993) 291-295.
5. [5] Goff, D.C., Tsai, G., Manoach, D.S. and Coyle, J.T., Dose-finding trial of D-cycloserine added to neuroleptics for negative symptoms in schizophrenia, Am. J. Psychiatry, 152 (1995) 1213-1215.
6. 14C]serine, Enzyme, 28 (1981) 43-48.
7. [7] Ishimaru, M., Kurumaji, A. and Toru, M., Increases in strychnine-insensitive glycine binding sites in cerebral cortex of chronic schizophrenics: evidence for glutamate hypothesis, Biol. Psychiatry, 35 (1994) 84-95.
8. [8] Javitt, D.C., Zylberman, I., Zukin, S.R., Heresco-Levy, U. and Lindenmayer, J.P., Amelioration of negative symptoms in schizophrenia by glycine, Am. J. Psychiatry, 151 (1994) 1234-1236.
9. 3H]MK-801 binding in rat brain sections,. Brain Res. 710 (1996) 103-111.
10. [10] Meltzer, H. Y., The mechanism of action of clozapine in relation to its clinical advantages. In H.Y. Meltzer (Ed.), Novel Antipsychotic Drugs, Raven Press, New York, 1992.
11. [11] Nowak, L., Bregestovski, P., Ascher, P., Herbet, A. and Prochiantz, Z., Magnesium gates glutamate-activated channels in mouse central neurones, Nature, 307 (1984) 462-465.
12. [12] Rehavi, M. and Schnitzer, E., Long-term desipramine or chlorpromzine and rat brain N-methyl-D-aspartate receptor, J. Basic Clin. Physiol. Pharmacol., 2 (1991) 111-121.
13. 3H]MK-801 binding to the N-methyl-D-aspartate receptor reveals drug interactions with the zinc and magnesium binding sites, J. Pharmacol. Exp. Ther., 247 (1988) 1025-1031.
14. 2+ and polyamines independently of the arcaine-sensitive site, J. Neurochem., 62 (1994) 54-62.
15. [15] Sherman, A.D., Davidson, A.W., Baruah, S. et al., Evidence of glutamatergic deficiency in schizophrenia, Neurosci. Lett., 121 (1991) 77-80.
16. [16] Tarazi, F.I., Florijn, W.J. and Cresse, I., Chronic effects of typical and atypical neuroleptics on glutamate receptor subtypes, Schizophrenia Res., 15 (1995) 168-169.
17. [17] Tsai, G., Gastfriend, D.R. and Coyle, J.T., The glutaminergic basis of human alcoholism,. Am. J. Psychiatry, 152 (1995) 332-340.
18. [18] Ulas, J., Nguyen, L. and Cotman, C.W., Chronic haloperidol treatment enhances binding to NMDA receptors in rat cortex, NeuroReport, 4 (1993) 1049-1051.
19. [19] Young, A.B. and Fagg, G.E., Excitatory amino acid receptors in the brain: membrane binding and receptor autoradiographic approaches, Trends Pharmacol. Sci., 11 (1990) 126-133.