메뉴 건너뛰기




Volumn 105, Issue 2, 1996, Pages 249-255

Tirapazamine (SR 4233) interrupts cell cycle progression and induces apoptosis

Author keywords

Aerobic cytotoxicity; Apoptosis; Mitotic index; SR 4233; Tirapazamine

Indexed keywords

DNA FRAGMENT; TIRAPAZAMINE;

EID: 0030564996     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3835(96)04292-9     Document Type: Article
Times cited : (12)

References (17)
  • 1
    • 0027288316 scopus 로고
    • SR 4233 (Tirapazamine): A new anticancer drug exploiting hypoxia in solid tumor
    • [1] Brown, J.M. (1993) SR 4233 (Tirapazamine): a new anticancer drug exploiting hypoxia in solid tumor. Br. J. Cancer, 67, 1163-1170.
    • (1993) Br. J. Cancer , vol.67 , pp. 1163-1170
    • Brown, J.M.1
  • 3
    • 0027396881 scopus 로고
    • Toxicology of daily administration to mice of the radiation potentiator SR 4233 (WIN 59075)
    • [3] Spiegel, J.F., Spear, M.A. and Brown, J.M. (1993) Toxicology of daily administration to mice of the radiation potentiator SR 4233 (WIN 59075). Radiother. Oncol., 26, 79-81.
    • (1993) Radiother. Oncol. , vol.26 , pp. 79-81
    • Spiegel, J.F.1    Spear, M.A.2    Brown, J.M.3
  • 4
    • 0022260723 scopus 로고
    • The diethyldithiocarbamate concentration effects and interactions with other cytotoxic agents on Chinese hamster cells (V79)
    • [4] Lin, P.S., Quamo, S., Ho, K.C. and Baur, K. (1985) The diethyldithiocarbamate concentration effects and interactions with other cytotoxic agents on Chinese hamster cells (V79). Radiat. Res., 102, 271-282.
    • (1985) Radiat. Res. , vol.102 , pp. 271-282
    • Lin, P.S.1    Quamo, S.2    Ho, K.C.3    Baur, K.4
  • 5
    • 0027361250 scopus 로고
    • Cytotoxicity and manganese superoxide dismutase induction by tumor necrosis factor-α and ionizing radiation in MCF-7 human breast carcinoma cells
    • [5] Lin, P.S., Ho, K.C., Sung, S.J. and Tsai, S. (1993) Cytotoxicity and manganese superoxide dismutase induction by tumor necrosis factor-α and ionizing radiation in MCF-7 human breast carcinoma cells. Lymphokine Cytokine Res., 12, 303-308.
    • (1993) Lymphokine Cytokine Res. , vol.12 , pp. 303-308
    • Lin, P.S.1    Ho, K.C.2    Sung, S.J.3    Tsai, S.4
  • 6
    • 0028041311 scopus 로고
    • The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2
    • [6] Carson, W.E., Haldar, S., Baiocchi, R.A., Croce, C.M. and Caligiuri, M.A. (1994) The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2. Proc. Natl. Acad. Sci. USA, 91, 7553-7557.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7553-7557
    • Carson, W.E.1    Haldar, S.2    Baiocchi, R.A.3    Croce, C.M.4    Caligiuri, M.A.5
  • 7
    • 0026518928 scopus 로고
    • Internucleosomal DNA fragmentation during phorbol ester-induced monocytic differentiation on Go/Gl arrest
    • [7] Gunji, H., Hass, R. and Kufe, D. (1992) Internucleosomal DNA fragmentation during phorbol ester-induced monocytic differentiation on Go/Gl arrest. J. Clin. Invest., 89, 954-960.
    • (1992) J. Clin. Invest. , vol.89 , pp. 954-960
    • Gunji, H.1    Hass, R.2    Kufe, D.3
  • 9
    • 0022493495 scopus 로고
    • SR 4233: A new bioreductive agent with high selective toxicity for hypoxic mammalian cells
    • [9] Zeman, E.M., Brown, J.M., Lemmon, M.J., Hirst, V.K. and Lee, W.W. (1986) SR 4233: a new bioreductive agent with high selective toxicity for hypoxic mammalian cells. Int. J. Radiat. Oncol. Biol. Phys., 12, 1239-1242.
    • (1986) Int. J. Radiat. Oncol. Biol. Phys. , vol.12 , pp. 1239-1242
    • Zeman, E.M.1    Brown, J.M.2    Lemmon, M.J.3    Hirst, V.K.4    Lee, W.W.5
  • 10
    • 0028168183 scopus 로고
    • SR-4233 (Tirapazamine) acts as an uncoupler of oxidative phosphorylation in human MCF-7 breast carcinoma cells
    • [10] Ara, G., Coleman C.N. and Teicher, B.A. (1994) SR-4233 (Tirapazamine) acts as an uncoupler of oxidative phosphorylation in human MCF-7 breast carcinoma cells. Cancer Lett., 85, 195-203.
    • (1994) Cancer Lett. , vol.85 , pp. 195-203
    • Ara, G.1    Coleman, C.N.2    Teicher, B.A.3
  • 11
    • 0028308248 scopus 로고
    • The effect of low pH and hypoxia on the cytotoxic effects of SR4233 and mitomycin C in vitro
    • [11] Skarsgard, L.D., Vinczan, A., Skwarchuk, M.W. and Chaplin, D.J. (1994) The effect of low pH and hypoxia on the cytotoxic effects of SR4233 and mitomycin C in vitro. Int. J. Radiat. Oncol. Biol. Phys., 29, 363-367.
    • (1994) Int. J. Radiat. Oncol. Biol. Phys. , vol.29 , pp. 363-367
    • Skarsgard, L.D.1    Vinczan, A.2    Skwarchuk, M.W.3    Chaplin, D.J.4
  • 12
    • 0024414046 scopus 로고
    • The differential hypoxic cytotoxicity of bioreductive agents determined in vitro by the MTT assay
    • [12] Stratford, I.J. and Stephens, M.A. (1989) The differential hypoxic cytotoxicity of bioreductive agents determined in vitro by the MTT assay. Int. J. Radiat. Oncol. Biol. Phys., 16, 973-976.
    • (1989) Int. J. Radiat. Oncol. Biol. Phys. , vol.16 , pp. 973-976
    • Stratford, I.J.1    Stephens, M.A.2
  • 13
    • 0014635770 scopus 로고
    • DNA repair in Chinese hamster cells of different sensitivities to ultra-violet light
    • [13] Cleaver, I.E. (1969) DNA repair in Chinese hamster cells of different sensitivities to ultra-violet light. Int. J. Radiat. Biol., 16, 277-285.
    • (1969) Int. J. Radiat. Biol. , vol.16 , pp. 277-285
    • Cleaver, I.E.1
  • 14
    • 0013973616 scopus 로고
    • X-Ray sensitivity during the cell generation cycle of cultured Chinese hamster cells
    • [14] Sinclair, W.K. and Morton, R.A. (1966) X-Ray sensitivity during the cell generation cycle of cultured Chinese hamster cells. Radiat. Res., 29, 450-474.
    • (1966) Radiat. Res. , vol.29 , pp. 450-474
    • Sinclair, W.K.1    Morton, R.A.2
  • 16
    • 0018100415 scopus 로고
    • DNA synthesis and cell survival after X-irradiation of mammalian cells treated with caffeine or adenine
    • [16] Griffths, T.D., Carpenter, J.G. and Dahle, D.B. (1978) DNA synthesis and cell survival after X-irradiation of mammalian cells treated with caffeine or adenine. Int. J. Radiat. Biol., 33, 493-405.
    • (1978) Int. J. Radiat. Biol. , vol.33 , pp. 493-1405
    • Griffths, T.D.1    Carpenter, J.G.2    Dahle, D.B.3
  • 17
    • 0026731996 scopus 로고
    • The significance of spontaneous and induced apoptosis in the gastrointestinal tract of mice
    • [17] Potten, C.S. (1992) The significance of spontaneous and induced apoptosis in the gastrointestinal tract of mice. Cancer Metastasis Rev., 11, 179-195.
    • (1992) Cancer Metastasis Rev. , vol.11 , pp. 179-195
    • Potten, C.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.