X-irradiation-induced changes of the prelysosomal and lysosomal compartments and proteolysis in HT-29 cells

Scanning Microscopy

Volumn 10, Issue 4, 1996, Pages 1079-1091

  Somosy, Z ^a   Takats A ^a   Bognar G ^a   Kovacs A L ^b   Telbisz, A ^b   Racz A ^c   Kovacs J ^b   Koteles G J ^a  

^a National Research Institute for Radiobiology and Radiohygiene Budapest   (Hungary)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^c Hungarian Army Inst   (Hungary)

Author keywords

Acid phosphatase activity; Autophagy; Cationized ferritin uptake; Cytoplasmic vacuolar compartments; Endosome; HT 29 cells; Lysosome; Morphometry; Protein degradation; X irradiation

Indexed keywords

ACID PHOSPHATASE; CARBON 14; COBALT 60; FERRITIN; IODINE 131; PLUTONIUM; VALINE;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CONTROLLED STUDY; ENDOSOME; ENZYME ACTIVITY; HUMAN; HUMAN CELL; ISOTOPE LABELING; LYSOSOME; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RADIATION DOSE; TRANSMISSION ELECTRON MICROSCOPY; X IRRADIATION;

ACID PHOSPHATASE; DOSE-RESPONSE RELATIONSHIP, RADIATION; FERRITINS; HT29 CELLS; HUMANS; LYSOSOMES; MICROSCOPY, ELECTRON; PROTEINS; VACUOLES; VALINE;

ANIMALIA;

EID: 0030561788     PISSN: 08917035     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Bradford HM (1976) A rapid sensitive method for the quantitation of micrograms quantities of protein utilising the principle of protein dye binding. Anal. Biochem. 72, 248-254.
2. Clark C, Willis ED (1980) Effect of irradiation on lysosomal enzyme activation in cultured macrophages. Br. J. Radiol. 38, 21-30.
3. Ericsson JLE (1969) Mechanisms of cellular autophagy. In: Lysosomes in Biology and Pathology. Vol. 2. Dingle JT, Fell HB (eds.). North-Holland Publishing Co., Amsterdam, London, pp. 345-394.
4. Maisin JR (1970) The ultrastructure of the lung of mice exposed to a supra-lethal dose of ionizing radiation on the thorax. Radiat. Res. 44, 545-564.
5. van Deurs B, Holm PK, Kayser L, Sandvig K, Hansen SH (1993) Multivesicular bodies in HEp-2 cells are maturating endosomes. Eur. J. Cell Biol. 61, 208-224.
6. Ward DM, Perou CM, Lloyd M, Kaplan J (1995) "Synchronised" endocytosis and intracellular sorting in alveolar macrophages: The early sorting endosome is a transient organelle. J. Cell Biol. 129, 1229-1240.
7. Zhang SX, Kobayashi T, Okad T, GarciadeSar E, Seguchi H (1991) Ultracytochemical localisation of acid phosphatase and trimeta-phosphatase activities in the transitional epithelium of the rat urinary bladder. J. Submicrosc. Cytol. Pathol. 23, 431-437.