A phase I study of weekly cisplatin and whole abdominal radiation for the treatment of Stage III and IV endometrial carcinoma: A Gynecologic Oncology Group Pilot study

Gynecologic Oncology

Volumn 63, Issue 3, 1996, Pages 299-303

  Reisinger, Susan A ^a,e   Asbury, Robert ^b   Liao, Shu Yuan ^c   Homesley, Howard D ^d  

^a THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

^e Coral Springs Radiat Ther Regl C ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CISPLATIN; CREATININE;

ABDOMINAL RADIOTHERAPY; ADULT; AGED; ARTICLE; BLOOD TOXICITY; CANCER CHEMOTHERAPY; CANCER STAGING; CHYLOUS ASCITES; CLINICAL ARTICLE; CLINICAL PROTOCOL; CLINICAL TRIAL; DIARRHEA; ENDOMETRIUM CARCINOMA; FEMALE; HUMAN; HUMAN TISSUE; INTESTINE RESECTION; INTRAVENOUS DRUG ADMINISTRATION; NAUSEA; PARAAORTIC LYMPH NODE; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; RADIATION ENTEROPATHY; TREATMENT FAILURE; VOMITING;

EID: 0030561382     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.1996.0326     Document Type: Article

References (13)

1. 1. Gibbons, S., Martinez, A., Schray, M., Podratz, K., Stanhope, R., Garton, G., Weiner, S., Brabbins, D., and Malkasian, G. Adjuvant whole abdominopelvic irradiation for high risk endometrial carcinoma, Int. J. Radiat. Oncol. Biol. Phys. 21, 1019-1025 (1991).
2. 2. Polish, R. A. Abdominal radiotherapy for cancer of the uterine cervix and endometrium, Int. J. Radiat. Oncol. Biol. Phys. 16, 1453-1458 (1989).
3. 3. Greer, B. E., and Hamberger, A. D. Treatment of intraperitoneal metastatic adenocarcinoma of the endometrium by the whole-abdomen moving-strip technique and pelvic boost irradiation, Gynecol. Oncol. 16, 365-373 (1983).
4. 4. Trope, C., Grundsell, H., Johnson, J. E., Grundsell, H., Johnson, J. E., and Cavallin-Stahl, F. A phase II study of cis-platinum for recurrent corpus cancer, Eur. J. Cancer 16, 1025-1026 (1980).
5. 5. Seski, J. C., Edwards, C. L., Jerson, J., and Rutledge, F. Cisplatin chemotherapy for disseminated endometrial cancer, Obstet. Gynecol. 59, 225 (1982).
6. 6. Edmondson, J. H., Krook, J. E., Hilton, J. F., Malkasian, G. D., Everson, L. K., Jeffries, J. A., and Maillard, J. A. Randomized phase II studies of cisplatin and a combination of cyclophosphamide-doxorubicin cisplatin (CAP) in patients with progestin-refractory advanced endometrial carcinoma, Gynecol. Oncol. 28, 20-24 (1987).
7. 7. Thigpen, J. T., Blessing, J. A., Homesley, H., Creasman, W. T., and Sutton, G. Phase II trial of cisplatin as first line chemotherapy in patients with advanced or recurrent endometrial carcinoma: A Gynecologic Oncology Group study, Gynecol. Oncol. 33, 68-70 (1989).
8. 8. Lentz, S. S., Schray, M. F., and Wilson, T. O. Chylous ascites after whole-abdomen irradiation for gynecologic malignancy, Int. J. Radiat. Oncol. Biol. Phys. 19, 435-438 (1990).
9. 9. Rubenstone, A. I., and Fitch, L. B. Radiation nephritis: A clinicopathologic study, Am. J. Med. 33, 545 (1962).
10. 10. Van Slyak, E. J., and Bermudez, G. A. Radiation nephritis, Yale J. Biol. Med. 41, 243 (1968).
11. 11. Coughhlin, C. T., and Richmond, R. C. Biologic and clinical developments of cisplatin combined with radiation: Concepts, utility projections for new trials, and the emergence of carboplatin, Semin. Oncol. 16(Suppl. 6), 31-44 (1989).
12. 12. Luxton, R. W., and Kunkler, P. B. Radiation nephritis, Acta Radiol. 2, 169 (1964).
13. 13. Loeffler, J. S., Rosen, E. M., Niloff, J. M., Howes, A. E., and Knapp, R. C. Whole abdominal irradiation for tumors of the uterine corpus, Cancer 61, 1332-1335 (1933).