Predictor of the rate of CD4 lymphocyte loss in HIV-1-seropositive asymptomatic hemophiliacs by in vitro immunoglobulin synthesis

Clinical Immunology and Immunopathology

Volumn 81, Issue 3, 1996, Pages 224-228

  Cavallin, Fernando ^a   Traldi, Agostino ^a   Di Gaetano, Rosa ^a   De Biasi, Ercole ^a   Davoli, Giorgio ^a   Gajo, Giovanni ^a   Tagariello, Giuseppe ^a   Zambello, Renato ^b  

^a Castelfranco Veneto Hospital   (Italy)

^b Istituto di Medicina Clinica Padova   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; HEMOPHILIA; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOGLOBULIN PRODUCTION; IN VITRO STUDY; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

EID: 0030560809     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1006/clin.1996.0182     Document Type: Article

References (29)

1. 1. Shearer, G. M., Payne, S. M., Joseph, L. J., and Biddison, W. E., Functional T-lymphocytes immunodeficiency in a population of homosexual men who do not exhibit symptoms of acquired immunodeficiency syndrome. J. Clin. Invest. 74, 496-506, 1984.
2. 2. Miedema, F., Chantal Petit, A., Terpstra, F., Shattenkerk, J. K., De Wolf, F., and Al, B. J., Immunological abnormalities in human immunodeficiency (HIV) infected asymptomatic homosexual men. J. Clin. Invest. 82, 1908-1914, 1988.
3. 3. Hofman, B., Jakobsen, K. B., Odum, N., Dickmeiss, E., Platz, P., and Ryder, L. P., HIV induced immunodeficiency. Relatively preserved phytohemoagglutinin as opposed to decrease pokeweed mitogen responses may be due to possibly preserved responses via CD2/phytohemoagglutinin pathway. J. Immunol. 142, 1874-1880, 1989.
4. 4. Van Noesel, C. J. M., Gruters, R. A., Terpstra, F. G., Scellekeus, P. T. A., Wan Lier, R., and Miedema, F., Functional and phenotypic evidence for a selective loss of memory T cells in asymptomatic HIV-1 infected men. J. Clin. Invest. 86, 293-299, 1990.
5. 5. Biaggiotti, R., Giudizi, M. G., Almerigogna, F., Mazzetti, M., Alessi, A., Del Prete, G. F., Rafanelli, D., Fiorilli, M., Morfini, M., and Romagnani, S., Abnormalities of in vitro immunoglobulin production in apparently healthy hemophiliacs: Relationship with alteration of T cell subsets and with HTLV-III seropositivity. Clin. Exp. Immunol. 63, 354-358, 1986.
6. 6. Teeuwsen, V. J., Logtenberg, T., Siebelink, K. H., Lange, J. M., Goudsmit, J., Uytdehaag, F. J., and Osterhaus, A. D., Analysis of the antigen and mitogen induced differentiation of B lymphocytes from asymptomatic human immunodeficiency virus-seropositive male homosexual. J. Immunol. 139, 2929-2935, 1987.
7. 7. Mizuma, H., Litwin, S., and Zolla-Pasner, S., B cell activation in HIV infection: Relationship of spontaneous immunoglobulin secretion to various immunological parameters. Clin. Exp. Immunol. 71, 410-416, 1988.
8. 8. Terpstra, F., Al, B., Roos, M., De Wolf, F., Goudsmit, J., and Scellekens, P. T. A., Longitudinal study of leucocyte function in homosexual seroconverted for HIV: Rapid and persistent loss of B cell function after HIV infection. Eur. J. Immunol. 19, 667-673, 1989.
9. 9. Lang, W., Perkins, H., Anderson, R. E., Royce, R., Jewell, N., and Winchelstein, W., Jr., Patterns of T-lymphocyte change with human immunodeficiency virus infection: From seroconvertion to development of AIDS. J. Acquired Immune Defic. Syndr. 2, 63-69, 1989.
10. 10. Cruz, E. F., Desco, M., Montes, M. G., Longo, N., Gonzales, B., and Zabay, J. M., Immunological and serological markers predictive of progression to AIDS in a cohort of HIV-1 infected drug users. AIDS 4, 987-994, 1990.
11. 11. Anderson, R. E., Shiboski, S. C., Royce, R., Jewell, N. P., Lang, W., and Winchelstein, W., Jr., CD8+ T lymphocytes and progression to AIDS in HIV-1 infected men: Some observations. AIDS 5, 213-215, 1991.
12. 12. Buseyne, F., and Riviere, Y., HIV-specific CD8+ T-cells immune responses and viral replication. AIDS 7, S81-S85, 1993.
13. 13. Cuthbert, R. J. C., Ludlam, C. A., Tucker, J., Steel, C. M., Beatson, D., and Rebus, S., Five year prospective study of HIV-1 infection in Edinburgh haemophilic cohort. Br. Med. J. 301, 956-961, 1990.
14. 14. Schwartlander, B., Bek, B., Skarabis, H., Koch, J., Burkowitz, J., and Koch, M. A., Improvement of predictive value of CD4 lymphocyte count by beta-2-microglobulin, immunoglobulin A, and erythrocyte sedimentation rate. AIDS 7, 813-821, 1993.
15. 15. De Wolf, F., Lange, J. M. A., Houweling, J. T. M., Mulder, J. W., Beemster, J., and Scellekens, T. P., Appearance of predictors disease progression in relation to the development of AIDS. AIDS 3, 563-569, 1989.
16. 16. Eyster, M. E., Ballard, J. O., Gail, M. H., Drummond, J. E., and Gordert, J. J., Predictive markers for the acquired immunodeficiency syndrome (AIDS) in haemophiliacs: Persistence of p24 antigen and low T4 cell count. Ann. Intern. Med. 110, 963-969, 1989.
17. 17. Goedert, J. J., Kessler, C. M., Aledort, L. M., Biggar, R. J., Andes, W. A., and White, G. G., A prospective study of human immunodeficiency virus type I infection and the development of AIDS in subject with haemophilia. N. Engl. J. Med. 321, 1141-1148, 1989.
18. 18. Anderson, R. E., Lang, W., Shiboski, S., Royce, R., Jewell, N., and Winchelstein, W., Use of beta-2-microglobulin level and CD4 lymphocyte count to predict development of acquired immunodeficiency syndrome in persons with acquired immunodeficiency virus infection. Arch. Intern. Med. 150, 73-77, 1990.
19. 19. Cavallin, F., Traldi, A., and Zambello, R., Phenotypical and functional evaluation of CD8+/S6F1+ T lymphocytes in hemophiliac individuals with HIV-1 infection. Clin. Exp. Immunol. 93, 51-55, 1993.
20. 20. Cavallin, F., Traldi, A., Di Gaetano, R., and Zambello, R., In vitro immunoglobulin synthesis as a CD4 lymphocyte depletion predictor in HIV-1 infected asymptomatic haemophiliacs. AIDS 8, 1728-1729, 1994.
21. 21. Amadori, A., Zamarchi, R., Veronese, M. L., Panozzo, M., Mazza, M. R., Barelli, A., Borri, A., and Chieco-Bianchi, L., B-activation during HIV infection. III. Down-regulating effect of mitogen. AIDS 5, 821-828, 1991.
22. 22. Pryjma, J., Munoz, J., Galbraith, R. M., Fudenberg, H. H., and Virella, G., Induction and suppression of immunoglobulin synthesis in cultures of human lymphocytes: Effects of pokeweed mitogen and Staphylococcus aureus Cowan I. J. Immunol. 124, 656-661, 1980.
23. 23. Ameisen, J. C., and Capron, A., Cell dysfunction and depletion in AIDS: The programmed cell death hypothesis. Immunol. Today 12, 102-105, 1991.
24. 24. Oyaizu, N., McCloskey, T. W., Coronesi, M., Chirmule, N., Kalyanaraman, V. S., and Pahwa, S., Accelerated apoptosis in peripheral blood mononuclear cells (PBMC) from human immunodeficiency virus type I infected patients in a CD4 cross-linked PBMCs from normal individuals. Blood 82, 3392-3400, 1993.
25. 25. Amadori, A., Zamarchi, R., Ciminale, V., Del Mistro, A., Siervo, S., Alberti, A., Colombatti, M., and Chieco-Bianchi, L., HIV-1 specific B cell activation. A major constituent of spontaneous B cell activation during HIV-1 infection. J. Immunol. 143, 2146-2152, 1989.
26. 26. Clerici, M., and Shearer, G. M., A Th1 to Th2 switch is a critical step in the etiology of HIV infection. Immunol. Today 14, 107-111, 1993.
27. 27. Romagnani, S., Human TH1 and TH2 subsets: Doubt no more. Immunol. Today 12, 256-257, 1991.
28. 28. Levi, J. A., HIV pathogenesis and long-term survival. AIDS 7, 1401-1410, 1993.
29. 29. Clerici, M., and Shearer, G., The Th1-Th2 hypothesis of HIV-1 infection: New insights. Immunol. Today 15, 575-581, 1994.