Milk fat components: Possible chemopreventive agents for cancer and other diseases

Australian Journal of Dairy Technology

Volumn 51, Issue 1, 1996, Pages 24-32

  Parodi, P W ^a  

^a Dairy R and D Corporation   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0030558534     PISSN: 00049433     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (86)

1. Berdel, W.E. (1991), Membrane-interactive lipids as experimental anticancer drugs. Br. J. Cancer. 64, 208-11.
2. Blank, M.L., Cress, E.A., Smith, Z.L. and Snyder, F. (1991), Dietary supplementation with ether-linked lipids and tissue lipid composition. Lipids, 26, 166-9.
3. Bitman, J. and Wood, D.L. (1990), Changes in milk fat phospholipids during lactation. J. Dairy Sci. 73, 1208-16.
4. Bostick, R.M., Potter, J.D., Sellers, T.A., McKenzie, D.R., Kushi, L.H. and Folson, A.R. (1993), Relation of calcium, vitamin D, and dairy food intake to incidence of colon cancer among older women. Am. J. Epidemiol. 137, 1302-17.
5. Calabresse, C., Venturini, L., Ronco, G., Villa, P., Chomienne, C. and Belpomme, D. (1993), Butyric acid and its monosaccharide ester induce apoptosis in the HL-60 cell line. Biochem. Biophys. Res. Commun. 195, 31-8.
6. Carroll, K.K. (1991), Dietary fats and cancer. Am. J. Clin. Nutr. 53, 1064S-67S.
7. Carroll, K.K. and Khor, H.T. (1971), Effect of level and type of dietary fat on incidence of mammary tumors induced in female Sprague-Dawley rats by 7,12-dimethyl benz (a) anthracene. Lipids. 6, 415-20.
8. Chao, R., Khan, W. and Hannun, Y.A. (1992), Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. J. Biol. Chem. 267, 23459-62.
9. Chen, Z-X. and Breitman, T.R. (1994), Tributyrin: A prodrug of butyric acid for potential clinical application in differentiation therapy. Cancer Res. 54, 3494-9.
10. Chin, S.F., Storkson, J.M., Albright, K.J., Cook, M.E. and Pariza, M.W. (1994), Conjugated linoleic acid is a growth factor for rats as shown by enhanced weight gain and improved feed efficiency. J. Nutr. 124, 2344-9.
11. Christie, W.W., Noble, R.C. and Davies, G. (1987), Phospholipids in milk and dairy products. J. Soc. Dairy Technol. 40, 10-12.
12. Cook, M.C., Miller, C.C., Park, Y. and Pariza, M. (1993), Immune modulation by altered nutrient metabolism: Nutritional control of immune-induced growth depression. Poultry Sci. 72, 1301-5.
13. Cope, R.B. and Reeve, V.E. (1994), Modification of 7, 12-dimethyl-benzanthracene (DMBA) ultraviolet radiation (UVR) co-carcinogenesis, UVR carcinogenesis and immune suppression due to UVR and cis-urocanic acid by dietary fats. Photochem. Photobiol. 59, 24S.
14. Cope, R.B., Reeve, V.E., Bosnic, M. and Boehm-Wilcox, C. (1995), Protection from photocarcinogenesis by dietary fats and involvement of eicosanoids in their modulating effect on photoimmunosuppression. Photochem. Photobiol. 61, 103S.
15. Das, A.K., Holmes, R.D., Wilson, G.N. and Hajra, A.K. (1992), Dietary ether lipid incorporation into tissue plasmalogens of humans and rodents. Lipids. 27, 401-5.
16. Dbaibo, G.S., Obeid, L.M. and Hannun, Y.A. (1993), Tumor necrosis factor-« (TNF-α) signal transduction through ceramide. J. Biol. Chem. 268, 17762-6.
17. Deschner, E.E., Ruperto, J.F., Lupton, J.R. and Newmark, H.L. (1990), Dietary butyrate (tributyrin) does not enhance AOM-induced colon tumorigenesis. Cancer Lett. 52, 79-82.
18. Dillehay, D.L., Webb, S.K., Schmelz, E-M. and Merrill, A.H. (1994), Dietary sphingomyelin inhibits 1,2-dimethylhydrazine-induced colon cancer in CFI mice. J. Nutr. 124, 615-20.
19. Diomede, L., Colotta, F., Piovani, B., Re, F., Modest, E.J. and Salmona, M. (1993), Induction of apoptosis in human leukemic cells by the ether lipid 1-oetadecyl-2-methyl-rac-glycerol-3-phosphocholine. A possible basis for its selective action. Int. J. Cancer. 53, 124-30.
20. Eibl, H., Hilgard, P. and Unger, C. (1992), Alkylphosphocholines: New drugs in cancer therapy. Introduction. Prog. Expml. Tumor Res. 34, ix-x.
21. Elson, C.E. and Yu, S.G. (1994), The chemoprevention of cancer by mevalonate-derived constituents of fruits and vegetables. J. Nutr. 124, 607-14.
22. Fraser, D.R. (1995), Vitamin D. Lancet. 345, 104-7.
23. Freeman, H.J. (1986), Effects of differing concentrations of sodium butyrate on 1,2-dimethylhydrazine-induced rat intestinal neoplasia. Gastroenterology, 91, 596-602.
24. Gaziano, J.M. and Hennekens, C.H. (1993), The role of beta-carotene in the prevention of cardiovascular disease. Ann. N. Y. Acad. Sci. 691, 148-55.
25. Hallgren, B. and Larsson, S. (1962), The glyceryl ethers in man and cow. J. Lipid Res. 3, 39-43.
26. Hallgren, B., Niklasson, A., Stallberg, G. and Thorin, H. (1974), On the occurrence of 1-0 alkylglycerols and 1-0(2-methoxyalkyl)glycerols in human colostrum, human milk, cow's milk, sheep's milk, human red bone marrow, red cells, blood plasma and a uterine carcinoma. Acta Chem. Scand. B 28, 1029-34.
27. Hannun, Y.A. (1994), The sphingomyelin cycle and the second messenger function of ceramide. J. Biol. Chem. 269, 3125-8.
28. Hannun, Y.A. and Bell, R.M. (1993), The sphingomyelin cycle: A prototypic sphingolipid signalling pathway. Adv. Lipid Res. 25, 27-41.
29. Hannun, Y.A. and Linardic, C.M. (1993), Sphingolipid breakdown products: Anti-proliferative and tumor-suppressor lipids. Biochim. Biophys. Acta 1154, 223-36.
30. Heerdt, B.G., Houston, M.A. and Augenlicht, L.H. (1994), Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res. 54, 3286-94.
31. Hennekens, C.H., Mayrent, S.L. and Willett, W. (1986), Vitamin A, Carotenoids, and retinoids. Cancer. 58, 1837-41.
32. Hill, D.L. and Grubbs, C.J. (1992), Retinoids and cancer prevention. Annu. Rev. Nutr. 12, 161-81.
33. Hron, R.J., Koltun, S.P., Pominski, J. and Abraham, G. (1987), The potential commercial aspects of gossypol. J. Am. Oil Chem. Soc. 64, 1315-9.
34. Hu, Y-F., Chang, C-J.G., Brueggemeier, R.W. and Lin, Y.C. (1994), Presence of antitumor activities in the milk collected from gossypoltreated dairy cows. Cancer Lett. 87, 17-23.
35. Hussey, H.J. and Tisdale, M.J. (1994), Effect of poly unsaturated fatty acids on the growth of murine colon adenocarcinomas in vitro and in vivo. Br. J. Cancer. 70, 6-10.
36. Imaizumi, K., Tominaga, A., Sato, M. and Sugano, M. (1992), Effects of dietary sphingolipids on levels of serum and liver lipids in rats. Nutr. Res. 12, 543-8.
37. Ip, C., Scimeca, J.A. and Thompson, H.J. (1994), Conjugated linoleic acid. Cancer. 74, 1050-4.
38. Jarvis, W.D., Kolesnick, R.N., Fornari, F.A., Traylor, R.S., Gewirtz, D.A. and Grant, S. (1994), Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway. Proc. Natl. Acad. Sci. 91, 73-7.
39. Kim, M-Y., Linardic, C., Obeid, L. and Hannun, Y. (1991), Identification of sphingomyelin turnover as an effector mechanism tor the action of tumor necrosis factor a and γ-interferon. J. Biol. Chem. 266, 484-9.
40. Klurfeld, D.M. (1995), Fat effects in experimental tumorigenesis. J. Nutr. Biochem. 6, 201-5.
41. Klurfeld, D.M., Weber, M.M. and Kritchevsky, D. (1983a), Inhibition of chemically induced colon or breast cancer by milk fat and milk solids. Fed. Proc. 42, 802.
42. Klurfeld, D.M., Weber, M.M. and Kritchevsky, D. (1983b), Comparison of semipurifled and skim milk protein containing diets on DMBA-induced breast cancer in rats. Kiel. Milchwirtschaft. Forschun. 35, 421-2.
43. Knekt, P., Heliovaara, M., Rissanen, A., Aromaa, A. and Aaran, R-K. (1992), Serum antioxidant vitamins and risk of cataract. Br. Med. J. 305, 1392-4.
44. 3 enhances the expression of transforming growth factor β1 and its latent form binding protein in cultured breast carcinoma cells. Cancer Res. 55, 1540-6.
45. Krinsky, N.I. (1991), Effects of carotenoids in cellular and animal systems. Am. J. Clin. Nutr. 53, 238s-46s.
46. Lee, K.N., Kritchevsky, D. and Pariza, M.W. (1994), Conjugated linoleic acid and atherosclerosis in rabbits. Atherosclerosis. 108, 19-25.
47. Lidbeck, A. Nord, C.E., Gustafsson, J-A. and Rafter, J. (1992), Lactobacilli, anticarcinogenic activities and human intestinal microflora. Eur. J. Cancer Prev. 1, 341-53.
48. McIntosh, G.H., Regester, G.O., LeLeu, R.K., Royle, P.J. and Smithers, G.W. (1995), Diary proteins protect against dimethylhydrazine induced intestinal cancers in rats. J. Nutr. 125, 809-16.
49. McIntyre, A., Gibson, P.R. and Young, G.P. (1993), Butyrate production from dietary fibre and protection against large bowel cancer in a rat model. Gut. 34, 386-91.
50. Merrill, A.H (1991), Cell regulation by sphingosine and more complex sphingolipids. J. Bioenerg. Biomembr. 23, 83-104.
51. Messina, M.J., Persky, V., Setchell, K.D.R. and Barnes, S. (1994), Soy intake and cancer risk: A review of the in vitro and in vivo data. Nutr. Cancer. 21, 113-31.
52. Michal, J.J., Chew, B.P., Shultz, T.D., Wong, T.S. and Magnuson, N.S. (1992), Interaction of conjugated dienoic derivatives of linoieic acid with β-carotene on cellular host defence. FASEB. J. 6, A1102.
53. Miller, A.A., Kurschel, E., Osieka, R. and Schmidt, C.G. (1987), Clinical pharmacology of sodium butyrate in patients with acute leukemia. Eur. J. Cancer Clin. Oncol. 23, 1283-7.
54. Miller, C.C., Park, Y., Pariza, M.W. and Cook, M.E. (1994), Feeding conjugated linoleic acid to animals partially overcomes catabolic responses due to endotoxin injection. Biochem. Biophys. Res. Commun. 198, 1107-12.
55. Moon, R.C. (1989), Comparative aspects of carotenoids and retinoids as chemopreventive agents for cancer. J. Nutr. 119, 127-134.
56. Moriwaki, H. and Muto, T. (1992), Retinoids and cancer chemoprevention. J. Nutr. Sci. Vitaminol. Special issue. S-10-2. 317-20.
57. Newberne, P.M., Bueche, D., Riengropitak, S. and Schrager, T.F. (1990), The influence of dietary levels of vitamin A and fat on colon cancer. Nutr. Cancer. 13, 235-42.
58. Newmark, H.L. and Lipkin, M. (1992), Calcium, Vitamin D, and colon cancer. Cancer Res. 52, 2067-70.
59. Newmark, H.L., Lupton, J.R. and Young, C.W. (1994), Butyrate as a differentiating agent: Pharmacokinetics, analogues and current status. Cancer Lett. 78, 1-5.
60. Nicolosi, R.J., Courtemanche, K.V., Laitinen, L., Scimeca, J.A. and Huth, P.J. (1993), Effect of feeding diets enriched in conjugated linoleic acid on lipoproteins and aortic atherogenesis in hamsters. Circulation. 88, I-457.
61. Nilsson, A. (1968), Metabolism of sphingomyelin in the intestinal tract of the rat. Biochim. Biophys. Acta. 164, 575-84.
62. Nordin, B.E.C. and Morris, H.A. (1992), Osteoporosis and vitamin D. J. Cell. Eiochem. 49, 19-25.
63. Norman, A.W. (1990), Intestinal calcium absorption: A vitamin D-hormone mediated adaptive response. Am. J. Clin. Nutr. 51, 290-300.
64. Novogrodsky, A., Duir, A., Ravid, A., Shkolnik, T., Stenzel, K.H., Rubin, A.L. and Zaizov, R. (1983), Effect of polar organic compounds on leukemic cells. Cancer. 51, 9-14.
65. Obeid, L.M., Linardic, C.M., Karolak, L.A. and Hannun, Y.A. (1993), Programmed cell death induced by ceramide. Science. 259, 1769-71.
66. Ohta, H., Sweeney, E.A., Masamune, A., Yatomi, Y., Hakamori, S-I, and Igarashi, Y. (1995), Induction of apoptosis by sphingosine in human leukemic HL-60 cells: A possible endogenous modulator of apoptotic DNA fragmentation occurring during phorbol ester-induced differentiation. Cancer Res. 55, 691-7.
67. Osada, K., Nagira, K., Teruya, K., Tachibana, H., Shirahata, S. and Murakami, H. (1994), Enhancement of interferon-β production with sphingomyelin from fermented milk. Biotherapy. 7, 115-23.
68. Parodi, P.W. (1960), The vitamin A potency of southern Queensland butters. Aust. J. Dairy Technol. 15, 13-17.
69. Parodi, P.W. (1970), Fatty acid composition of Australian butter and milk fat. Aust. J. Dairy Technol. 25, 200-5.
70. Parodi, P.W. (1994), Conjugated linoleic acid: An anticarcinogenic fatty acid present in milk fat. Aust. J. Dairy. Technol. 49, 93-7.
71. Pouillart, P., Cerutti, I., Ronco, G., Villa, P. and Chany, C. (1991), Butyric monosaccharide ester-induced cell differentiation and antitumor activity in mice. Importance of their prolonged biological effect for clinical applications in cancer therapy. Int. J. Cancer. 49, 89-95.
72. Pouillart, P., Cerutti, I., Ronco, G., Villa, P. and Chany, C. (1992), Enhancement by stable butyrate derivatives of antitumor and antiviral actions of interferon. Int. J. Cancer. 51, 596-601.
73. Prasad, K.N. (1980), Butyric acid: A small fatty acid with diverse biological functions. Life Sci. 27, 1351-8.
74. Rabizadeh, E., Shaklai, M., Nudelman, A., Eisenbach, L. and Rephaeli, A. (1993), Rapid alteration of c-myc and c-jun expression in leukemic cells induced to differentiate by a butyric acid prodruct. FEBS Lett. 328, 225-9.
75. Reddy, B.S. and Rivenson, A. (1993), Inhibitory effect of Bifidobacterium longum on colon, mammary, and liver carcinogenesis induced by 2-amino-3-methylimidazo[4,5-f] quinoline, a food mutagen. Cancer Res. 53, 3914-8.
76. Schmelz, E-M., Grail, K.J., Larocque, R., Dillehay, D.L. and Merrill, A.H. (1994), Uptake and metabolism of sphingolipids in isolated intestinal loops of mice. J. Nutr. 124, 702-12.
77. Smith, P.J. (1986), n-Butyrate alters chromatin accessibility to DNA repair enzymes. Carcinogenesis. 7, 423-9.
78. Tallman, M.S. and Wiernik, P.H. (1992), Retinoids in cancer treatment. J. Clin. Pharmacol 32, 868-88.
79. Van Poppel, G. (1993), Carotenoids and cancer: An update with emphasis on human intervention studies. Eur. J. Cancer. 29A, 1335-44.
80. Wolf, G. (1993), Retinoids and carotenoids as inhibitors of carcinogenesis and inducers of cell-cell communication. Nutr. Rev. 50, 270-4.
81. Yanagi, S., Yamashita, M. and Imai, S. (1993), Sodium butyrate inhibits the enhancing effect of high fat diet on mammary carcinogenesis. Oncology. 50, 201-4.
82. Yanagi, S., Yamashita, M., Ogoshi, K. and Imai, S. (1994), Comparative effects of milk, yogurt, butter, and margarine on mammary tumorigenesis induced by 7,12-dimethylbenz (a) anthracene in rats. Cancer Detect. Prev. 18, 415-20.
83. Yanagi, S., Yamashita, M., Sakamoto, M. Kumazawa, K. and Imai, S. (1989), Comparative effects of butter, margarine safflower oil and dextrin on mammary tumorgenesis in mice and rats. In Kabara, J.J. (Ed.) The pharmacological effects of lipids. III. Role of lipids in cancer research. Champaign, IL., American Oil Chemists Society, 159-69.
84. Yanagi, S., Yamashita, M., Tsuyuki, M., Morimoto, J., Haga, S. and Imai, S. (1992), Milk cream does not enhance 2,7-dimethylbenz[a] anthracene-induced mammary tumorigenesis. Cancer Lett. 61, 141-5.
85. Yu, S.G., Abuirmeileh, N.M., Qureshi, A.A. and Elson, C.E. (1994), Dietary β-ionone suppresses hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. J. Agric. Food Chem. 42, 1493-6.
86. Ziegler, R.G. (1989), A review of epidemiologic evidence that carotenoids reduce the risk of cancer. J. Nutr. 119, 116-22.