Neuron loss, mossy fiber sprouting, and interictal spikes after intrahippocampal kainate in developing rats

Epilepsy Research

Volumn 26, Issue 1, 1996, Pages 219-231

  Leite, João P ^a,b,c   Babb, Thomas L ^d   Pretorius, James K ^a   Kuhlman, Paula A ^a   Yeoman, Kristin M ^a   Mathern, Gary W ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d LERNER RESEARCH INSTITUTE   (United States)

Author keywords

epilepsy; ontogeny NIH image; synaptic reorganization

Indexed keywords

KAINIC ACID;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; HIPPOCAMPUS; MALE; MOSSY FIBER; NEWBORN; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; RAT; TEMPORAL LOBE EPILEPSY;

AGE FACTORS; ANIMALS; CELL COUNT; DISEASE MODELS, ANIMAL; ELECTROENCEPHALOGRAPHY; EPILEPSY; EPILEPSY, TEMPORAL LOBE; FUNCTIONAL LATERALITY; HIPPOCAMPUS; HUMANS; KAINIC ACID; MALE; NERVE REGENERATION; NEUROFIBRILS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0030550268     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(96)00055-1     Document Type: Conference Paper

References (51)

1. [1] Abercrombie, M., Estimation of nuclear population from microtome sections, Anat. Rec., 94 (1946) 239-247.
2. [2] Albala, B.J., Moshé, S.L. and Okada, R., Kainic acid-induced seizures: A developmental study, Dev. Brain Res., 13 (1984) 139-148.
3. [3] Altman, J. and Bayer, S., Postnatal development of the hippocampal dentate gyrus under normal and experimental conditions. In: R.L. Isaacson and K.H. Pribram, (Eds.), The Hippocampus, Structure and Development, Vol. 1, Plenum, New York, 1975, pp. 95-122.
4. [4] Amaral, D.G. and Dent, J.A., Development of the mossy fibers of the dentate gyrus: I. A light and electron microscopic study of the mossy fibers and their expansions, J. Comp. Neurol., 195 (1981) 51-86.
5. [5] Annegers, J.F., Hauser, W.A., Elveback, L.R. and Kurkland, L.T., The risk of epilepsy following febrile convulsions, Neurology, 29 (1979) 297-303.
6. [6] Annegers, J.F., Hauser, W.A., Shirts, S.B. and Kurland, L.T., Factors prognostic of unprovoked seizures after febrile convulsions, New Engl. J. Med., 316 (1987) 493-498.
7. [7] Babb, T.L. and Brown, W.J., Pathological findings in epilepsy. In: J. Engel, Jr. (Ed.), Surgical Treatment of the Epilepsies, Raven Press, New York, 1987, pp. 511-540.
8. [8] Babb, T.L., Kupfer, W.R., Pretorius, J.K., Crandall, P.H. and Levesque, M.F., Synaptic reorganization by mossy fibers in human epileptic fascia dentata, Neuroscience, 42 (1991) 351-363.
9. [9] Ben-Ari, Y., Tremblay, E., Berger, M. and Nitecka, L., Kainic acid seizure syndrome and binding sites in developing rats, Dev. Brain Res., 14 (1984) 284-288.
10. [10] Cherubini, E., De Feo, M.R., Mecarelli, O. and Ricci, G.F., Behavioral and electrographic patterns induced by systemic administration of kainic acid in developing rats, Dev. Brain Res., 9 (1983) 69-77.
11. [11] Cook, T.M. and Crutcher, K.A., Extensive target cell loss during development results in mossy fibers in the regio superior (CA1) of the rat hippocampal formation, Dev. Brain Res., 21 (1985) 19-30.
12. [12] Cook, T.M. and Crutcher, K.A., Intrahippocampal injection of kainic acid produces significant pyramidal cell loss in neonatal rats, Neuroscience, 18 (1986) 79-92.
13. [13] Cronin, J., Obenaus, A., Houser, C.R. and Dudek, F.E., Electrophysiology of dentate granule cells after kainate-induced synaptic reorganization of the mossy fibers, Brain Res., 573 (1992) 305-310.
14. [14] de Lanerolle, N.C., Kim, J.H., Robbins, R.J. and Spencer, D.D., Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy, Brain Res., 495 (1989) 387-395.
15. [15] Dunn, D.W., Status epilepticus in children: Etiology, clinical features, and outcome, J. Neurol. Child., 3 (1988) 167-173.
16. [16] Falconer, M.A., The pathological substrate of temporal lobe epilepsy, Guy's Hosp. Rep., 119 (1970) 47-60.
17. [17] Gastaut, H., Toga, M., Roger, J. and Gibson, W.C., A correlation of clinical electroencephalographic and anatomical findings in nine autopsied cases of temporal lobe epilepsy, Epilepsia, 1 (1959) 56-85.
18. [18] Gotman, J., Automatic recognition of epileptic seizures in the EEG, Electroencephalogr. Clin. Neurophysiol., 54 (1982) 530-540.
19. [19] Holmes, G.L. and Thompson, J.L., Effects of kainic acid on seizure susceptibility in the developing brain, Dev. Brain Res., 39 (1988) 51-59.
20. [20] Houser, C.R., Miyashiro, J.E., Swartz, B.E., Walsh, G.O., Rich, J.R. and Delgado-Escueta, A.V., Altered patterns of dynorphin immunoreactivity suggest mossy fiber reorganization in human hippocampal epilepsy, J. Neurosci., 10 (1990) 267-282.
21. [21] Leite, J.P., Babb, T.L., Mathern, G.W., Pretorius, J.K. and Seki, T., Axonal growth and terminal specialization of mossy fibers in developing rat pups: An NCAM-H and Neo-Timm's study, Soc. Neurosci. Abstr., 20 (1994) 1682.
22. [22] Lorente de Nó, R., Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system, J. Psych. Neurol., 45 (1933) 113-177.
23. [23] Magloczky, Z.S. and Freund, T.F., Selective neuronal death in the contralateral hippocampus following unilateral kainate injections into the CA3 subfield, Neuroscience, 56 (1993) 317-336.
24. [24] Margerison, J.H. and Corsellis, J.A.N., Epilepsy and the temporal lobes, Brain, 89 (1966) 499-530.
25. [25] Mathern, G.W., Kupfer, W.R., Pretorius, J.K., Babb, T.L. and Levesque, M.F., Onset and patterns of hippocampal sprouting in the rat kainate seizure model: Evidence for progressive cell loss and neo-innervation in regio inferior and superior, Dendron, 1 (1992) 69-84.
26. [26] Mathern, G.W., Cifuentes, F., Leite, J.P., Pretorius, J.K. and Babb, T.L., Hippocampal EEG excitability and chronic spontaneous seizures are associated with aberrant synaptic reorganization in the rat intrahippocampal kainate model, Electroencephalogr. Clin. Neurophysiol., 87 (1993) 326-339.
27. [27] Mathern, G.W., Babb, T.L, Vickrey, B.G., Melendez, M., Pretorius, J.K., Traumatic compared to non-traumatic clinical-pathologic associations in temporal lobe epilepsy, Epilepsy Res., 19 (1994) 129-139.
28. [28] Mathern, G.W., Pretorius, J.K. and Babb, T.L., Quantified patterns of mossy fiber sprouting and neuron densities in hippocampal and lesional seizures, J. Neurosurg., 82 (1995) 211-219.
29. [29] Mathern, G.W., Pretorius, J.K. and Babb, T.L., Influence of the type of initial precipitating injury and at what age it occurs on course and outcome in patients with temporal lobe seizures, J. Neurosurg., 82 (1995) 220-227.
30. [30] Mathern, G.W., Babb, T.L., Vickrey, B.C., Melendez, M. and Pretorius, J.K., The clinical-pathogenic mechanisms of hippocampal neuron loss and surgical outcomes in temporal lobe epilepsy, Brain, 118 (1995) 105-118.
31. [31] Maytal, J., Shinnar, S., Moshé, S.L. and Alvarez, L.A., The low morbidity and mortality of status epilepticus in children, Pediatrics, 83 (1989) 323-331.
32. [32] McNamara, J.O., Cellular and molecular basis of epilepsy, J. Neurosci., 14 (1994) 3413-3425.
33. [33] Meldrum, B.S., Vigouroux, R.A. and Brierley, J.B., Systemic factors and epileptic brain damage, Arch. Neurol., 29 (1973) 82-87.
34. [34] Moshé, S.L., Sperber, E.F. and Valisek, L., Critical issues of developmental seizure disorders, Physiol. Res., 42 (1993) 145-154.
35. [35] Nelson, K.B. and Ellenberg, J.H., Predictors of epilepsy in children who have experienced febrile seizures, New Engl. J. Med., 295 (1976) 1029-1033.
36. [36] Nitecka, L., Tremblay, E., Charton, G., Bouillot, J.P., Berger, M.L. and Ben-Ari, Y., Maturation of kainic acid seizure-brain damage syndrome in the rat. II. Histopathological sequelae, Neuroscience, 13 (1984) 1073-1094.
37. [37] Pérez-Clausell, J. and Dansher, G., Intravesicular localization of zinc in rat telencephalic boutons. A histochemical study, Brain Res., 337 (1985) 91-98.
38. [38] Ribak, C.E. and Navetta, M.S., An immature mossy fiber innervation of hilar neurons may explain their resistance to kainate-induced cell death in 15 day old rats, Dev. Brain Res., 79 (1994) 47-62.
39. [39] Sagar, H.J. and Oxbury, J.M., Hippocampal neuron loss in temporal lobe epilepsy: Correlation with early childhood convulsions, Ann. Neurol., 22 (1987) 334-340.
40. [40] Seki, T. and Arai, Y., Highly polysialylated neural cell adhesion molecule (NCAM-H) is expressed by newly generated granule cells in the dentate gyrus of the adult rat, J. Neurosci., 1313 (1993) 2351-2358.
41. [41] Sherwood, N.M. and Timiras, P.S., A Stereotaxic Atlas of the Developing Rat Brain, UC Press, Los Angeles, 1970.
42. [42] Sloviter, R.S, Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats, Neurosci. Lett., 137 (1992) 91-96.
43. [43] Sperber, E.F., Haas, K.Z., Stanton, P.K. and Moshé, S.L., Resistance of the immature brain to seizure-induced synaptic reorganization, Dev. Brain Res., 60 (1991) 88-93.
44. [44] Sperber, E.F., Stanton, P.K., Haas, K., Ackermann, R.F., Moshé, S.L., Developmental differences in the neurobiology of epileptic brain damage. In: J. Engel, Jr., C. Wasterlain, E.A. Cavalheiro, U. Heinemann and G. Avanzini (Eds.), Molecular Neurobiology of Epilepsy. Epilepsy Res., Suppl. 9, Elsevier, Amsterdam, 1992, pp. 67-81.
45. [45] Sutula, T., Cascino, G., Cavazos, J., Parada, I. and Ramirez, L., Mossy fiber synaptic reorganization in the epileptic human temporal lobe, Ann. Neurol., 26 (1989) 321-330.
46. [46] Tauck, D.L., Nadler, J.V., Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid treated rats, J. Neurosci., 5 (1985) 1016-1022.
47. [47] Thompson, K.W., Holm, A.M. and Wasterlain, C.G., Loss of hippocampal interneurons in a model of neonatal status epilepticus, Soc. Neurosci. Abstr., 20 (1994) 1668.
48. [48] Tremblay, E., Nitecka, L., Berber, M.L. and Ben-Ari, Y., Maturation of kainic acid seizure-brain damage syndrome in the rat. I. Clinical, electrographic and metabolic observations, Neuroscience, 13 (1984) 1051-1072.
49. [49] Wasterlain, C.G. and Sankar, R., Excitotoxicity and the developing brain. In: G. Avanzini, R. Fariello, U. Heinemann and R. Mutani (Eds.), Epileptogenic and Excitotoxic Mechanisms, John Libbey & Company Ltd., New York, 1993, pp. 135-151.
50. [50] Wasterlain, C.G. and Shirasaka, Y., Seizures, brain damage and brain development, Brain Dev., 16 (1994) 279-295.
51. [51] Zimmer, J. and Haug, F.M., Laminar differentiation of the hippocampus, fascia dentata and subiculum in developing rats, observed with the Timm sulphide silver method, J. Comp. Neurol., 179 (1978) 581-618.