Nutrition and the development of Osteochondrosis (Dyschondroplasia)

Pferdeheilkunde

Volumn 12, Issue 3, 1996, Pages 338-342

  Jeffcott, L B ^a   Savage, C J ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Energy; Minerals; Nutrition; Osteochondrosis

Indexed keywords

EID: 0030546718     PISSN: 01777726     EISSN: None     Source Type: Journal    
DOI: 10.21836/pem19960337     Document Type: Article

References (39)

1. Atteh, J.O. and Leeson, L. (1984): Effects of dietary saturated or unsaturated fatty acids and calcium levels on performance and mineral metabolism of broiler chickens. Poult. Sci. 63, 2252-2260.
2. Boulet, M. and Marier, J.R. (1961): Precipitation of calcium phosphates from solutions at near physiological concentrations. Arch. Biochem. Biophys. 93, 157-165.
3. Bridges, C.H. and Harris, E.D. (1988): Experimentally induced cartilage fractures (osteochondritis dissecans) in foals fed low copper diets. J. Am. Vet. Med. Assoc. 193, 215-221.
4. Bruin, G. and Creemers, J. (1994): Het vorkómen van osteochondrose. Praktijkonderzoek Paardenhouderij, Maart, 15-17.
5. Corbellini, C.N., Krook, L., Nathanielsz, P.W. and Kallfelz, F.A. (1991): Osteochondrosis in fetuses of ewes overfed calcium. Calcif. Tissue Int. 48, 37-45.
6. Cuervo, L.A., Pita, J.C. and Howell, D.S. (1971): Ultramicroanalysis of pH, PSG and carbonic anhydrase activity at calcifying sites in cartilage. Calcif. Tiss. Res.7, 220-231.
7. Cymbaluk, N.F., Schryver, H.F. and Hintz, H.F. (1981): Influence of dietary molybdenum on copper metabolism in ponies. J. Nutr. 111, 96-106.
8. Ekman, S. (1990): The normal and osteochondrotic porcine articular-epiphyseal cartilage. Studies on cellular and matrix components. PhD Thesis, Uppsala, Sweden.
9. Glade, M.J. (1992): A review of hormonal regulation of cartilage growth in foals. Proc. Equine Osteochondrosis in the '90s. Abstract, pp19-20.
10. Glade, M.J. and Belling, T.H. (1986): A dietary etiology for osteochondrotic cartilage. Equine Vet. Sc. 6, 151-155.
11. Glade, M.J., Beller, D., Bergen, J., Berry, D., Blonder, E., Bradley, J., Cupelo, M. and Dallas, J. (1985): Dietary protein in excess of requirements inhibits renal calcium and phosphorus reabsorption in young horses. Nutr. Rep. Int. 31, 649-659.
12. Glade, M.J., Gupta, S. and Reimers, T.J. (1984): Hormonal response to high and low planes of nutrition in weanling Thoroghbreds. J. Anim. Sci. 59, 658-665.
13. Gunson, D.E., Kowalczyk, D.F., Shoop, C.R. and Ramberg, C.F. (1982): Environmental zinc and cadmium pollution associated with generalized Osteochondrosis, osteoporosis, and nephrocalcinosis in horses. J. Am. Vet. Med. Assoc. 180, 295-299.
14. Hedhammar, A., Wu, F., Krook, L., Schryver, H.F., de Lahunta, A., Whalen, J.P., Kallfelz, F.A., Nunez, E.A., Hintz, H.F., Steffy, B.E. and Ryan, G.D. (1974): Overnutrition and skeletal disease. An experimental study in growing Great Dane dogs. Cornell Vet. 64, Suppl 5, 1-160.
15. Hintz, H.F. and Schryver, H.F. (1987): Nutrition. In: Current therapv in equine medicine 2. (Robinson, N.E. ed), W.B. Saunders Co., Philadelphia. pp 387-405.
16. Hurtig, M.B., Green, S.L., Dobson, H. and Burton, J. (1990): Defective bone and cartilage in foals fed a low-copper diet. In: Proc Am Assoc. Equine Pract. 36, pp637-643.
17. Jeffcott, L.B. (1991): Osteochondrosis in the horse - searching for the key to pathogenesis. Equine Veterinary Journal 23, 331-338.
18. Knight, D.A., Gabel, A.A., Reed, S.M., Bramlage, L.R., Tyznik, W.I. and Embertson, R.M. (1985): Correlation of dietary mineral to incidence and severity of metabolic bone disease in Ohio and Kentucky. In: Proc Am. Assoc. Equine Pract. 31, pp445-461.
19. Knight, D.A., Weisbrode, S.E., Schmall, L.M. and Gabel, A.A. (1987): Copper supplementation and cartilage lesions in foals. In: Proc. Am. Assoc. Equine Pract. 33, pp191-194.
20. Knight, D.A., Schmall, L.M., Reed, S.M., Bramlage, L.R. and Gabel, A.A. (1992): The influence of dietary copper and growth rate on cartilage defects in foals. In: Proc. Equine Osteochondrosis in the '90s. Abstract pp22-23.
21. Kowalczyk, D.F., Gunson, D.E., Shoop, C.R. and Ramberg, C.F. (1986): The effects of natural exposure to high levels of zinc and cadmium in the immature pony as a function of age. Environ. Res. 40, 285-300.
22. Krook, L. and Maylin, G.A. (1988): Fractures in Thoroughbred race horses. Cornell Vet. 78, Suppl 11, 5-133.
23. Leach, D. (1990): New information on conformation, locomotion and lameness. In: Proc. Postgrad. Coom. Vet. Sc. Uni. Syd. 30, Equine lameness and foot conditions, pp162-167.
24. Leedle, R.A., Raub, R.H., Anderson, K.P. and Wilson, J. (1995): Influence of excessive nutrition and exercise on the incidence of orthopaedic lesions in weanling horses. Equine vet J. (in press).
25. Lilburn, M.S., Lauterio, T.J., Ngiam-Rilling, K. and Smith, J.M. (1989): Relationships among mineral balances in diet, early growth manipulation and incidence of tibial dyschondroplasia in different strains of meat type chickens. Poultry Sci. 68, 1263-1273.
26. Meakim, D.W., Hintz, H.F., Schryver, H.F. and Lowe, J.E. (1981): The effect of dietary protein on calcium metabolism and growth of the weanling foal. In: Proc. Cornell Nutr. Conf. Feed Manufacturers, pp95-101.
27. National Research Council (1989): Nutrient Requirements of Horses, 5th rev. ed., Washington DC, National Academy Press.
28. Pool, R.R. (1987): Developmental orthopedic disease in the horse. Normal and abnormal bone formation. In: Proc. Am. Assoc. Equine Pract. 33, pp143-158.
29. Savage, C.J. (1992): The influence of nutrition on skeletal growth and induction of osteochondrosis (dyschondroplasia) in horses. PhD Thesis, Melbourne, Australia.
30. Savage, C.J., McCarthy, R.N. and Jeffcott, L.B. (1993a): Effects of dietary energy and protein on induction of dyschondroplasia in foals. Equine vet J., Suppl. 16, 74-79.
31. Savage, C.J., McCarthy, R.N. and Jeffcott, L.B. (1993b): Effects of dietary phosphorus and calcium on induction of dyschondroplasia in foals. Equine vet J., Suppl. 16, 80-83.
32. Savage, C.J., McCarthy, R.N. and Jeffcott, L.B. (1993c): Histomorphometrical assessment of bone biopsies from foals fed diets high in phosphorus and digestible energy. Equine vet J., Suppl. 16, 89-93.
33. Schryver, H.F., Meakim, D.W., Lowe, J.E., Williams, J., Soderholm, L.V. and Hintz, H.F. (1987): Growth and calcium metabolism in horses fed varying levels of protein. Equine vet J. 19, 280-287.
34. Smith, B. Fischer, G., Poulos, P. et al. (1975): Abnormal bone development and lameness associated with secondary copper deficiency in young cattle. J. Am. Vet. Med. Assoc. 166, 682-688
35. Smith, J.D., Jordan, R.M. and Nelson, M.L. (1975): Tolerance of ponies to high levels of dietary copper. J. Anim. Sci. 41, 1645-1649.
36. th ed., Lea and Febiger, Philadelphia. USA.
37. Stephens, L.C., Norrdin, R.W. and Benjamin, S.A. (1985): Effects of calcium supplementation and sunlight exposure on growing beagle dogs. Am. J. Vet. Res. 46, 2037-2042.
38. Strickland, K. Smith, F. Woods, M. and Mason, D. (1987): Dietary molybdenum as a putative copper antagonist in the horse. Equine Vet. J. 19, 50-54
39. Thompson, K.N., Baker, J.D. and Jackson, S.G. (1988): The influence of high dietary intakes of energy and protein on third metacarpal characteristics of weanling ponies. Equine Vet. Sc. 8, 391-394.