Prospects for rational approaches to anthelmintic discovery

Parasitology

Volumn 113, Issue SUPPL., 1996, Pages

  Thompson, D P ^a  

^a PFIZER INC   (United States)

Author keywords

comparative neuropharmacology; high throughput screens; mechanism based screens; neuroreceptors; nutrient dependent viability assay; rational drug discovery

Indexed keywords

ANTHELMINTIC AGENT; CYCLO(DEXTRO LACTYL N METHYLLEUCYL DEXTRO 3 PHENYLLACTYL N METHYLLEUCYL DEXTRO LACTYL N METHYLLEUCYL DEXTRO 3 PHENYLLACTYL N METHYLLEUCYL); IVERMECTIN; LEVAMISOLE; PARAHERQUAMIDE; UNCLASSIFIED DRUG;

DRUG DESIGN; DRUG TARGETING; HELMINTHIASIS; MEDICAL RESEARCH; NERVOUS SYSTEM; NEUROMUSCULAR SYSTEM; NEUROPHARMACOLOGY; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EID: 0030513840     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/s0031182000077994     Document Type: Review

References (2)

1. ALBRECHT, S. & WALTER, R. D. (1991). Hallucinogenic and neuroleptic drug interactions with potential neurotransmitter receptors in parasitic nematodes. Molecular and Biochemical Parasitology 45, 289-96.
2. ANGELD, M., ORTWINE, D., WORTH, D., WERBEL, L. M. & McCALL, J. W. (1983). Synthesis and antifilarial activity of N-[4-[[4-alkoxy-3-[(dialkylamino) methyl]phenyl]amino]-2-pynmidinyl]-N′-phenyl-guanidines. Journal of Medicinal Chemistry 26, 1258-67.