Antibodies to glutamic acid decarboxylase in the prediction of insulin dependency

Diabetes Research and Clinical Practice

Volumn 34, Issue SUPPL., 1996, Pages

  Zimmet, Paul ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

antibodies to glutamic acid decarboxylase; insulin dependent diabetes mellitus; latent autoimmune diabetes in adults

Indexed keywords

ENZYME ANTIBODY; GLUTAMATE DECARBOXYLASE; INSULIN;

AUTOIMMUNITY; CHILD; CONFERENCE PAPER; DIAGNOSIS; DRUG THERAPY; EPIDEMIOLOGY; ETIOLOGY; HUMAN; INSULIN DEPENDENCE; INSULIN DEPENDENT DIABETES MELLITUS; PREDICTION;

EID: 0030511925     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8227(96)90019-4     Document Type: Conference Paper

References (31)

1. Thai, A.C. and Eisenbarth, G.S. (1993) Natural history of IDDM. Diabetes Rev. 1, 1-14.
2. Tuomilehto, J., Zimmet, P., Mackay, I.R., et al. (1994) Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before the clinical onset of the disease. Lancet 343, 1383-1385.
3. Palmer, J.P. (1993) Predicting IDDM. Use of humeral immune markers. Diabetes Rev. 1, 104-115.
4. Clare-Salzler, M.J., Tobin, A.J. and Kaufman, D.L. (1992) Glutamate decarboxylase: an autoantigen in IDDM. Diabetes Care 15, 132-135.
5. Hou, J., Said, C., Franchi, D., Dockstader, P. and Chatterjee, N.K. (1994) Antibodies to glutamic acid decarboxylase and P2-C peptides in sera from Coxsackie virus B4-infected mice and IDDM patients. Diabetes 43, 1260-1266.
6. Kaufman, D.L., Clarc-Salzler, M., Tian, J., et al. (1993) Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature 336, 69-72.
7. Tisch, R., Yang, X-D., Singer, S.M., Liblau, R.S., Fugger, L. and McDevitt, H.O. (1993) Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature 366, 72-75.
8. Zimmet, P.Z., Elliott, R.B., Mackay, I.R., Tuomi, T., Rowley, M.J., Pilcher, C.C. and Knowles, W.J. (1994) Autoantibodies to glutamic acid decarboxylase and insulin in presymptomatic insulin-dependent diabetes mellitus: frequency and segregation by age and gender. Diabetic Med. 11, 866-871.
9. Baekkeskov, S., Kristensen, J.K., Srikanta, S., et al. (1987) Antibodies to a M 64 000 human islet cell antigen precede the clinical onset of insulin dependent diabetes. J. Clin. Invest. 79, 926-934.
10. Atkinson, M.A., Maclaren, N.K., Scharp, D.W., Lacy, P.E., and Riley, W.J. (1990) 64000 M, autoantibodies as predictors of insulin-dependent diabetes. Lancet 335, 1357-1360.
11. Rowley, M.J., Mackay, I.R., Chen, Q.-Y., Knowles, W.J. and Zimmet, P. (1992) Antibodies to glutamic acid decarboxylase discriminate major types of diabetes mellitus. Diabetes 41, 548-551.
12. Chen, Q.-Y., Rowley, M.J., Bryne, G.C., et al. (1993) Antibodies to glutamic acid decarboxylase in Australian children with insulin-dependent diabetes mellitus and their first-degree relatives. Pediatr. Res. 34, 785-790.
13. Verge, C.F., Howard, N.J., Rowley, M.J., et al. (1994) Anti-glutamate decarboxylase and other antibodies at the onset of childhood IDDM: a population-based study. Diabetologia 37, 1113-1120.
14. Baekkeskov, S., Aanstoot, H.-J., Christgau, S., et al. (1990) Identification of the 64 K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase. Nature 347, 151-156.
15. Bingley, P.J., Bonifacio, E., Shattock, M., et al. (1993) Can islet cell antibodies predict IDDM in the general population? Diabetes Care 16, 45-50.
16. National Diabetes Data Group. (1979) Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 28, 1039-1057.
17. World Health Organization Expert Committee on Diabetes Mellitus. (1980) Second Report. Technical Report Series 646. WHO. Geneva, pp. 8-12.
18. Zimmet, P.Z., Tuomi, T., Mackay, I.R., et al. (1994) Latent autoimmune diabetes mellitus in adults (LADA) the role of antibodies to glutamic acid decarboxylase in diagnosis and prediction of insulin dependency. Diabetic Med. 11, 299-303.
19. Groop, L., Pelkonen, R., Roakimiej, S., Bottazzo, G. and Doniach, D. (1986) Secondary failure treatment with oral antidiabetic agents in non-insulin-dependent diabetes. Diabetes Care 9, 129-132.
20. Scott, R.S. and Brown, L.J. (1991) Prevalence and incidence of insulin-treated diabetes mellitus in adults in Canterbury, New Zealand. Diabetic Med. 8, 1-8.
21. Tuomilehto, J., Nissinen, A., Kivela, S.L., et al. (1986) Prevalence of diabetes mellitus in elderly men aged 65 to 84 years in Eastern and Western Finland. Diabetologia 29, 611-615.
22. Mølbak, A.G., Christau, B., Marner, B., Borch-Johnsen, K. and Nerup, J. (1994) Incidence of insulin-dependent diabetes mellitus in age groups over 30 years in Denmark. Diabetic Med. 11, 650-655.
23. Gleichmann, H., Zörcher, B., Greulich, B., et al. (1984) Correlation of islet cell antibodies and HLA-DR phenotypes with diabetes mellitus in adults. Diabetologia 27, 90-92.
24. Groop, L.C., Bottazzo, G.F. and Doniach, D. (1986) Islet cell antibodies identify latent type I diabetes in patients aged 35-75 years at diagnosis. Diabetes 35, 237-241.
25. Harris, M.I. and Zimmet, P. (1992) Classification of diabetes mellitus and other categories of glucose intolerance. In: H. Keen, R. DeFronzo, K.G.M.M. Alberti and P. Zimmet (Eds.), The International Textbook of Diabetes Mellitus, John Wiley, London, pp. 3-18.
26. Groop, L., Miettinen, A., Groop, P.H., Meri, S., Koskimies, S. and Bottazzo, G.F. (1988) Organ-specific auto-immunity and HLA-DR antigens as markers for B-cell destruction in patients with type 2 diabetes. Diabetes 37, 99-103.
27. Tuomi, T., Groop, L.C., Zimmet, P.Z., Rowley, M.J., Knowles, W. and Mackay, I.R. (1993) Antibodies to glutamic acid decarboxylase reveal latent autoimmune diabetes mcllitus in adults with a non-insulin dependent onset of disease. Diabetes 42, 359-362.
28. Scott, R., Willis, J., Brown, L., et al. (1993) Antibodies to glutamic acid decarboxylase (GAD) predict insulin-deficiency in adult onset diabetes mellitus. Diabetes 42, (Suppl 1) 220A.
29. Hagopian, W.A., Karlsen, A.E., Gottsater, A., et al. (1993) Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD65) shows that 65 K autoantibody positivity at onset predicts diabetes type. J. Clin. Invest. 91, 368-374.
30. Zimmet, P.Z., Shaten, B.J., Kuller, L.H., Rowley, M.J., Knowles, W.J. and Mackay, I.R. for the MRFIT Research Group. (1994) Antibodies to glutamic acid decarboxylase and diabetes mellitus in the multiple risk factor intervention trial. Am. J. Epidemiol. 140, 683-690.
31. Landin-Olsson, M., Nilsson, K.O., Lernmark, Å. and Sundkvist, G. (1990) Islet cell antibodies and fasting C-peptide predict insulin requirement at diagnosis of diabetes mellitus. Diabetologia 33, 561-568.