Catalytic performance of a supramolecular bienzyme complex formed with artificial aminotransferase and natural lactate dehydrogenase

Chemistry Letters

Volumn , Issue 6, 1996, Pages 427-428

  Kikuchi, Jun Ichi ^a   Kamijyo, Yasuyuki ^a   Etoh, Hiroshi ^a   Murakami, Yukito ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0030500932     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.1996.427     Document Type: Article

References (8)

1. Y. Murakami and J. Kikuchi, in "Bioorganic Chemistry Frontiers," ed by H. Dugas, Springer-Verlag, Berlin (1991), Vol. 2, p. 73; Y. Murakami, J. Kikuchi, Y. Hisaeda, and O. Hayashida, Chem. Rev., in press.
2. Y. Murakami and J. Kikuchi, in "Bioorganic Chemistry Frontiers," ed by H. Dugas, Springer-Verlag, Berlin (1991), Vol. 2, p. 73; Y. Murakami, J. Kikuchi, Y. Hisaeda, and O. Hayashida, Chem. Rev., in press.
3. J. Kikuchi, Z.-Y. Zhang, and Y. Murakami, J. Am. Chem. Soc., 117, 5383 (1995).
4. Y. Murakami, J. Kikuchi, K. Akiyoshi, and T. Imori, J. Chem. Soc., Perkin Trans. 2, 1986, 1445.
5. On fusion behavior of the single-walled vesicles formed with the peptide lipids as evaluated by DSC, see: Y. Murakami, J. Kikuchi, and T. Takaki, Bull. Chem. Soc. Jpn., 59, 3145 (1986).
6. J. J. Holbrook, A. Liljas, S. J. Steinsel, and M. G. Rossmann, in "The Enzymes," ed by P. D. Boyer, Academic Press, New York (1975), 3rd ed, Vol. 11, p. 191.
7. 3 the former ions are not suitable in the present bienzyme system due to the following reasons: the transamination mediated by copper(II) ions is too fast to follow the reaction by HPLC, and the LDH activity is strongly inhibited by copper(II) ions.
8. A. Meister, J. Biol. Chem., 184, 117 (1949).